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28 July 2020

Ergot Alkaloid ELISA now available from Randox Food Diagnostics

Available now, the Randox Food Diagnostics Ergot Alkaloid ELISA (Catalogue Number EA3491) is:

Compliant with the lowest proposed maximum levels being considered by the European Commission for the total of 12 main ergot alkaloids applicable from July 2020, including the stricter drafted limits from July 2022, for cereal-based feed, wheat and rye milling products.

Accurately detects the sum of 12 main ergot alkaloids to test the most affected type of cereal – rye flour. Randox’s ELISA results show an excellent 95% correlation with the assigned concentration within FAPAS Proficiency Test scheme.

Unrivalled in the detection of low contamination levels. The Z-score of FAPAS PT of -0.6 for baby multigrain food was obtained using Randox Ergot Alkaloids ELISA.

Validated based on Commission Regulation (EC) No 519/2014 as a semi-quantitative screening method for cereal-based feed, wheat and rye milling products. The same regulation was followed for fit-for-purpose approach assessment for confirmatory method, which approves Randox Ergot Alkaloids ELISA as being a method for official control. It is successfully assessed by fit-for-purpose approach according to Commission Regulation (EC) No 401/2006 as approved method of analysis.

Evaluated by third-party laboratory (Wageningen Food Safety research / WFSR, 2019) and proved to be able to distinguish between negative and positive samples. Randox’s ELISA displayed no false-negatives and no false-positives in this study. Across all commercially available ELISA tests, Randox Food Diagnostics Ergot Alkaloids ELISA was the only test which showed good performance with all 3 sample types, including 11 matrices and a total of 24 samples.

      Reference reports are available upon request.

      For more information visit https://www.randoxfood.com/feed-and-cereals-analysis/ergot-alkaloids/ or email us directly at info@randoxfooddiagnostics.com

       

       

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      News       About Us       COVID-19

       

      25 July 2020

      COVID-19 Testing Service Testimonial: The Irish Football Association

      As we move towards a new ‘normal’ and sporting organisations begin the process of restarting their games, many teams will be wondering how to ensure a safe and reassuring training environment for their players and their staff.

      Thanks to our COVID-19 testing service, The Irish Football Association was able to facilitate a timely and efficient return to play by confirming their players as ‘COVID-safe.’

      Our ‘Back to Business’ programme has enabled the IFA to demonstrate their commitment to their players, their staff, and their fans, as well as get back to business by ensuring the highest level of safety.

      Corinne Lannie, Risk Manager at the Irish Football Association, commented;

      “The test kits were very straightforward to use.  The instructions were clear as was the YouTube guidance video. The recording onto the Randox system was easy and the speed of results was exceptional.

      “The support provided by Paul (Randox Business Development Executive) was amazing – he was extremely helpful and supportive and really went above and beyond.”

      At Randox, we offer two types of testing;

      PCR (diagnostic) testing, and antibody testing, which can give an indication that an individual has been previously infected with COVID-19.

      Sample collection services are available.

      David Hallendorff, Business Relations Manager at Randox Health commented;

      “Collectively we are all working towards a timely return to a more normal society, which will see companies reopening and people returning to work.

      “To facilitate this recovery of the economy, without compromising the health of workers or of the wider general public, workplaces have a responsibility to provide a safe working environment.

      “It is great to see so many companies putting the health of their staff as a priority and taking a proactive approach to testing.

      To find out more about our Back to Business COVID-19 Testing Service, please email info@randoxhealth.com or phone 0800 2545 130

       

       

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      News       About Us        Randox Toxicology

      Chicago’s Rising Fentanyl Problem: A Randox Toxicology Report

      Abuse of opioids, and in particular, fentanyl, has been on the rise in the United States in recent years. The number of patients being prescribed painkillers has almost quadrupled since the 90s from 76 million to 289 million in 2016. It has been described as a uniquely American problem, where pain relief prescriptions are about 40% higher than other developed countries.

      Inevitably due to the high addiction rate of opioids, this has unfortunately led to increasing overdose deaths. In 2017 alone over 70,000 people died from drug overdoses in the USA with opioids being involved in 67.8% of cases.

      Chicago Illinois is no exception to this crisis. The National Institute of Drug Abuse found that Illinois has a rate of 17.2 deaths per 100,000 people from opioid overdoses, compared to the national average of 14.6. It is not only prescription painkillers that are adding to the opioid addiction crisis in Chicago, but substances such as fentanyl that is illegally sold on the street.

      Fentanyl is a cheaper, synthetic opioid which can be 50 times more potent than heroin and 100 times more potent than morphine. It is commonly added to heroin to increase strength and cut costs. Many users believe they are purchasing heroin when in fact it can be mostly fentanyl, resulting in rising overdose deaths. The DEA’s Chicago lab have stated that the drug is making up a more of their workload than ever and becoming a regular drug they see.

      Randox Toxicology

      Randox Toxicology are world leaders in drug testing solutions with the capability of detecting over 500 drug and drug metabolites using our innovative Biochip Array Technology – the most comprehensive on the drug testing market. Using our revolutionary patented Biochip Array Technology, the Evidence MultiSTAT is a fully automated benchtop analyzer that enables on-site simultaneous detection of up to 21 classical, prescription and synthetic drugs of abuse from a single sample.

      Designed to work across a variety of matrices including; whole blood, urine, and oral fluid our patented multi-analyte testing platform provides a complete and highly accurate toxicology profile in 17-20 minutes. Most impressively the MultiSTAT has been designed to be fully operated from sample input to results output by someone with absolutely no laboratory experience and in any environment.

      To find out more about our Biochip Array Technology and our Evidence Series range of analysers, visit www.randoxtoxicology.com or email info@randoxtoxicology.com

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      STATEMENT FROM RANDOX: TEMPORARY PRECAUTIONARY MEASURE

      16 July 2020

      As an immediate precautionary measure we have temporarily suspended distribution of sample collection kits using one particular batch / supplier of swabs. This is a temporary measure and does not apply to our private business which uses a different supplier of swabs.

      Test results from Randox kits are not affected.

      For more information please contact the Randox PR team by emailing randoxpr@randox.com

       

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      Randox Biosciences          Acute Kidney Injury          COVID-19

      15 July 2020

       

      The Importance of Early Detection of Acute Kidney Injury in COVID-19 patients

      Randox are proud to provide an early detection assay, capable of detecting Acute Kidney Injury in COVID-19 positive patients. AKI is an innovative diagnostic tool with the ability to identify four early and highly sensitive markers of kidney injury.

      The National Institute for Health and Care Excellence has highlighted that is important that COVID-19 patients are assessed for AKI on admission to hospital or transfer, monitored for AKI throughout their stay and that AKI is managed appropriately if it develops. (NICE, 2020)

      The novel test, which includes biomarkers recommended by the U.S. Food and Drug Administration and the European Medicines Agency detects KIM-I, NGAL, Cystatin C, and Clusterin.

      Kidney failure associated with COVID-19 is emerging as a common side effect with further studies underway. Early detection to prevent further renal damage, is vital for an individual’s long-term health, wellbeing and overall survival.

      The biomarkers on the Randox AKI Biochip have been identified as more sensitive than traditional testing methods, which, based on urine output and levels of serum creatinine, are grossly insensitive and not specific for the accurate diagnosis and monitoring of AKI.

      The Randox AKI assay provides results in 2.5 hours. The new testing panel also facilitates increased lab efficiency and reduced sample prep from the laboratory technician. Using just one urine sample, Randox’s patented Biochip Technology tests for all four AKI biomarkers simultaneously, resulting in time and cost saving benefits, which drive towards an increase in clinical performance.

      For further information on our Acute Kidney Injury Array please visit the Randox Biosciences website.

      For any other enquiries please email info@randoxbiosciences.com

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      09 July 2020

      Alcohol consumption during the COVID-19 pandemic

       

      Alcohol consumption during the COVID-19 pandemic

      On 31 December 2019, the Wuhan Municipal Health Commission in Wuhan City, Hubei province, China, reported a cluster of 27 pneumonia cases (including seven severe cases) of unknown aetiology, with a common reported link to Wuhan’s Huanan Seafood Wholesale Market, a wholesale fish and live animal market. On 23 January 2020, Wuhan City was locked down – with all travel in and out of Wuhan prohibited –and movement inside the city was restricted.

      By March, the World Health Organisation (WHO) declared COVID-19 a global pandemic, with more than 150 countries worldwide being affected. Many countries, including the UK; imposed stringent public health measures that included the closure of businesses & strict social distancing guidelines.

      Due to the enforced lockdown, many within the UK workforce had to make alternative working arrangements, with working from home becoming the new norm. With the closure of businesses and the hospitality sector including bars and restaurants, it meant people seeking alternative means to purchase and consume alcohol.

      Before the pandemic, alcohol was attributed to being a financial burden to the UK health system and wider economy. The British Medical Journal estimated that alcohol costs the NHS more than £3.5 billion and the wider economy at least £21bn each year.

      The organisation Alcohol Change UK commissioned new research to look at whether people’s drinking habits changed during the COVID-19 lockdown. Over 2,000 people completed the survey, with results weighted to ensure they were representative of the UK population.

      The key takeaway from the report is people are consuming alcohol differently because of the lockdown. Around one in five drinkers (21%) told us that they have been drinking more frequently since the lockdown. This suggests that around 8.6 million UK adults are drinking more frequently under lockdown.

      Furthermore, while almost half of drinkers said they were drinking about the same amount on a typical drinking day, 15% said they have been drinking more per session since lockdown.

      The Global Drug Survey produced a special report for COVID-19 with more than 80,000 participants. The report stated that 44% of those who participated said the frequency of alcohol use increased. Reasons for this included ‘having more time to drink and feeling bored more often.’ However, 25.5% reported having decreased their use of alcohol during COVID-19.

      As restrictions begin to ease and more people return to work, it is important to highlight the impact of COVI-19 on the workforce. People’s way of life has changed dramatically, with this change comes different ways of consuming alcohol. It is important to note that the figures above are a proportionate representation based on those who took part, but valuable insights can be gained when looking at alcohol use. For employers who have staff returning to work, their safety is of paramount importance. This will include effectively managing substance misuse, should it be an issue in the workplace.

      Effects of Alcohol

      Alcohol’s impact on your body starts from the moment you take your first sip. While an occasional glass of wine or beer isn’t a cause for concern, the cumulative effects of drinking wine, beer, or spirits can take its toll.

      Consumption of alcohol can impact various parts of the body. Effects can range from weakening of the immune and digestive system, to inflammation and sugar level issues.

      Our ‘Effects Of’ Series provides educational posters that can be displayed in workplaces to highlight the dangers of alcohol. Click here for more information.

      About Randox Testing Services

      Randox Testing Services are a specialist in the workplace drug & alcohol testing sector. We provide a wide range of testing for companies who want to reduce the impact of substance misuse in the workplace. With a range of service options and expert staff on hand to provide help and training, our services will help to eradicate the impact of drugs and alcohol.

      Throughout the COVID-19 pandemic, RTS have continued to provide drug & alcohol testing services. At all times, we have ensured our staff are equipped to provide sensible advice and flexible solutions to drug & alcohol testing.

      We have provided each Collection Officer with full PPE to ensure they meet requirements for personal and professional safety. Full social distancing guidelines are followed at all times when possible whilst conducting testing. We will continue to advise and navigate companies through this period as more businesses return and testing is required.

      If you have any questions regarding drug & alcohol testing, contact us today.

      Web: www.randoxtestingservices.com

      Email: testingservices@randox.com

      Phone: +44 (0) 28 9445 1011

       

       

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      18 June 2020

      RX modena and Randox Reagents used in COVID-19 hospital in India

      Randox Laboratories has installed an RX modena into a COVID-19 hospital in India; the Netaji Subhash Chandra Bose Medical College in Madhya Pradesh state.

      The installation, which marks the first RX modena to be used in an Indian Government Medical College, replaces existing instrumentation in the Medical College laboratory, an initiative which was driven by College Dean Dr. Pradeep Kumar Kasar and Head of Department Dr. Ashok Kumar Sahu.

      The RX modena will cater for an additional 38 samples compared to the previous instrumentation, and is running a range of biochemistry tests that play a pivotal role in COVID-19 patient management, including C-Reactive Protein (CRP), Ferritin, and Lactate Dehydrogenase (LDH).

      Dr. Ashok Kumar Sahu, Head of Biochemistry at Netaji Subhash Chandra Bose Medical College, commented;

      “We are very pleased with the performance of the RX modena, and in particular with its wide menu of tests that can be utilized for COVID-19 patient management. Its high throughput and versatility have been a great support for the clinicians working in our COVID-19 hospital, in determining risk stratification, disease progression, and response to treatment.”

      The RX modena is a high volume, floor standing, fully automated clinical chemistry analyser with a world leading test menu which covers specific proteins, lipids, therapeutic drugs, antioxidants, diabetes and veterinary testing. The versatile analyser offers advanced methodologies with excellent correlation to the gold standard, and excellent reagent CV ranges.

      Shail Dholabhai, Randox India Sales Manager, commented;

       “We are delighted that the team at Netaji Subhash Chandra Bose Medical College have chosen the RX modena to fulfil the testing requirements of this COVID-19 hospital. Offering an unrivalled test menu of routine and specialized chemistries, the RX modena provides laboratories with the superior precision, reliability and accuracy that the Randox RX series is renowned for.

      “Capable of performing a total of 1200 tests per hour including ISE, the RX modena presents a new class of efficiency which will result in faster and more accurate diagnoses, and ultimately, lead to better patient outcomes.”

      Benefits of the RX modena

      • Capable of performing 800 photometric and a total of 1200 tests per hour including ISE.
      • World-leading extensive test menu covering routine chemistries, specific proteins, lipids, antioxidants, cardiac, diabetes and veterinary testing, offering cost savings through consolidation of routine and novel tests on a single platform.
      • Economic platform with low water consumption of less than 20 litres per hour saving on consumable costs. The RX modena also requires less than 5 minutes minimal maintenance.
      • Interactive touch-screen technology with integrated barcode readers for reagent and sample identification. Increased functionality with 13 wavelengths generated via diffraction grating (340-800nm) ensuring a multitude of chemistries are possible on one system.
      • Easy-to-use advanced Microsoft 10 software with a built-in Inventory Management System calculating the number of tests remaining, providing alerts of shortages and expired reagents and calibrators. The RX modena also features automatic test re-run function and sample dilution.
      • Dedicated reagent and sample pipettes to minimise the risk of errors and contamination. The RX modena also features a continuous loading hatch to allow for samples to be analysed quickly and easily during a run.
      • Advanced QC capabilities with daily, monthly and batch QC with data archiving, Levey-Jennings charts and automatic QC and calibration. There are also 7 different calibration options available.

      For further information about the RX modena click here. 

      For information about laboratory tools for COVID-19 patient management please click here.

      For other enquiries please contact marketing@randox.com

       

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      29 June 2020

      Matt Hancock and Lord Bethell support Randox in call for future focus on diagnostics

      Matt Hancock and Lord Bethell support Randox in call for future focus on diagnostics

      In a recent Opinion Piece in The Daily Telegraph, our Managing Director Dr Peter FitzGerald stressed the value of diagnostics, the important role it plays in public health, and the contribution it has made specifically during the COVID-19 pandemic.

      Whilst regrettable that it has taken a pandemic to bring the health diagnostics sector into focus, it is a positive step forward for healthcare that the huge national and international scope of our sector is now rightly acknowledged.

      Indeed, Dr FitzGerald’s commentary was acknowledged by both the Secretary of State for Health, Matt Hancock, and the Minister for Innovation, Jim Bethell.

      The Secretary of State noted that “Randox have played a vital role in building our global-scale diagnostics capacity.”

        It is clear that the diagnostics industry, inclusive of the work Randox has done in the field, has had a positive impact in the fight against COVID-19. We know that testing at scale is the most effective way to both save lives, and ensure a timely return to a more normal society.

        We are very proud of our staff, for their ongoing support, and for their commitment to the work that we do, which is making a real and positive difference.

        You can read Dr FitzGerald’s full Opinion Piece for The Daily Telegraph, on our own website, by clicking here.

        For further information please contact randoxpr@randox.com or phone 028 9442 2413

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        25 June 2020

        COVID-19 has shown UK leadership on diagnostics

        COVID-19 has shown UK leadership on diagnostics; we can now become a world leader

        An Opinion Piece by Dr Peter FitzGerald, Managing Director of Randox Laboratories, in The Daily Telegraph

        When I founded Randox Laboratories in 1982 in Antrim, Northern Ireland, I could not have envisaged that today we would be manufacturing more clinical diagnostic products than any other company in the UK. Whilst I am incredibly proud that Randox is taking a leading role in the national Covid-19 testing effort, it is deeply regrettable that it has taken this pandemic to bring the UK’s health diagnostics sector into focus.

        The pandemic represents the biggest diagnostics and health infrastructure challenge of modern times.  It has forced and necessitated a herculean collaborative effort from Government, the NHS and the private sector. This partnership has delivered a new trust and information sharing network which bodes well for the future.

        Ministers now know what we can do and rightly acknowledge the huge national and international scope of our sector and for global UK leadership and new skilled jobs.  The Government is right to highlight and reflect that too many of these critical sectors and supplies have been allowed to be offshored in recent years. This has consequently had implications for patient care and the support available for health workers.

        In March, the World Health Organisation’s Director General, Tedros Adhanom Ghebreyesus, said that he had a simple message to countries on how to deal with the COVID-19 outbreak that was sweeping the globe, this message was ‘Test, test, test.’ In the UK, mass testing was, at that time, simply not possible. Indeed, the Health Secretary, Matthew Hancock, acknowledged  that it was the lack of a significant domestic diagnostic industry that had impeded the Government’s initial efforts on testing, which is why we were behind Germany and other states.  He was right and much has already been done to re-shore capacity and re-set this policy alongside understanding the importance for future British sector leadership.

        Going forward, we can and must deliver a new and much tighter partnership between the NHS and private sector across diagnostics and preventative healthcare. Improved communication, co-operation and partnerships will grow British sector expertise, jobs and skills.  The potential for British leadership and success here is huge.

        Earlier this month, I had the pleasure of welcoming Northern Ireland Secretary, Brandon Lewis MP to see our new £30m specialist Covid-19 testing hub at the Randox Science Park in Northern Ireland.  This investment will create 200 new science, engineering and manufacturing jobs at the facility on top of our existing workforce. It was fast-tracked over the space of four weeks and is the first step in a wider diagnostics investment programme as part of Randox’s efforts to enhance our national Covid testing capacity.

        A wider appreciation of the value and resource support for diagnostics testing and preventative health policy is now overdue and timely especially when you consider that seventy per cent of all medical decisions are based on the results of lab tests.  This testing must now account for more than the two per cent of the national healthcare budget.   Alongside our major focus on R&D, our scientists work on pioneering research into a range of common illnesses such as cancer, cardiovascular disease and Alzheimer’s disease. With around twenty five percent of turnover reinvested in R&D, Randox has more new tests in development than any other diagnostic company.  Our products are used across hospitals and veterinary laboratories, food testing, forensic toxicology and life sciences.

        Randox labs have spent over £305 million researching the thousands of biomarkers present in our bodies and have identified the gold standard in testing. Our patented Biochip Array Technology has revolutionized the diagnostics industry by offering a unique testing platform which allows multiple tests to be carried out from a single patient sample. On Covid, we have been able to include two tests on the same biochip; one specific and one confirmatory as recommended by the World Health Organisation.

        The ambition and determination to build a world-beating British diagnostics sector is overdue and right.  It offers so many advantages ranging from a healthier and happier population which lives longer to more skilled jobs in a sector which works hand in glove with our world beating academia and NHS.  The pandemic has rightly brought the UK’s diagnostics capability into sharp focus, and it is paramount that when we move to a post-Covid world, we take what we have learned from this crisis and build a self-reliant sector fit for the future.

          For further information please email randoxpr@randox.com

           

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