COVID-19 has shown UK leadership on diagnostics; we can now become a world leader
COVID-19 has shown UK leadership on diagnostics; we can now become a world leader
COVID-19 has shown UK leadership on diagnostics; we can now become a world leader
An Opinion Piece by Dr Peter FitzGerald, Managing Director of Randox Laboratories, in The Daily Telegraph
When I founded Randox Laboratories in 1982 in Antrim, Northern Ireland, I could not have envisaged that today we would be manufacturing more clinical diagnostic products than any other company in the UK. Whilst I am incredibly proud that Randox is taking a leading role in the national Covid-19 testing effort, it is deeply regrettable that it has taken this pandemic to bring the UK’s health diagnostics sector into focus.
The pandemic represents the biggest diagnostics and health infrastructure challenge of modern times. It has forced and necessitated a herculean collaborative effort from Government, the NHS and the private sector. This partnership has delivered a new trust and information sharing network which bodes well for the future.
Ministers now know what we can do and rightly acknowledge the huge national and international scope of our sector and for global UK leadership and new skilled jobs. The Government is right to highlight and reflect that too many of these critical sectors and supplies have been allowed to be offshored in recent years. This has consequently had implications for patient care and the support available for health workers.
In March, the World Health Organisation’s Director General, Tedros Adhanom Ghebreyesus, said that he had a simple message to countries on how to deal with the COVID-19 outbreak that was sweeping the globe, this message was ‘Test, test, test.’ In the UK, mass testing was, at that time, simply not possible. Indeed, the Health Secretary, Matthew Hancock, acknowledged that it was the lack of a significant domestic diagnostic industry that had impeded the Government’s initial efforts on testing, which is why we were behind Germany and other states. He was right and much has already been done to re-shore capacity and re-set this policy alongside understanding the importance for future British sector leadership.
Going forward, we can and must deliver a new and much tighter partnership between the NHS and private sector across diagnostics and preventative healthcare. Improved communication, co-operation and partnerships will grow British sector expertise, jobs and skills. The potential for British leadership and success here is huge.
Earlier this month, I had the pleasure of welcoming Northern Ireland Secretary, Brandon Lewis MP to see our new £30m specialist Covid-19 testing hub at the Randox Science Park in Northern Ireland. This investment will create 200 new science, engineering and manufacturing jobs at the facility on top of our existing workforce. It was fast-tracked over the space of four weeks and is the first step in a wider diagnostics investment programme as part of Randox’s efforts to enhance our national Covid testing capacity.
A wider appreciation of the value and resource support for diagnostics testing and preventative health policy is now overdue and timely especially when you consider that seventy per cent of all medical decisions are based on the results of lab tests. This testing must now account for more than the two per cent of the national healthcare budget. Alongside our major focus on R&D, our scientists work on pioneering research into a range of common illnesses such as cancer, cardiovascular disease and Alzheimer’s disease. With around twenty five percent of turnover reinvested in R&D, Randox has more new tests in development than any other diagnostic company. Our products are used across hospitals and veterinary laboratories, food testing, forensic toxicology and life sciences.
Randox labs have spent over £305 million researching the thousands of biomarkers present in our bodies and have identified the gold standard in testing. Our patented Biochip Array Technology has revolutionized the diagnostics industry by offering a unique testing platform which allows multiple tests to be carried out from a single patient sample. On Covid, we have been able to include two tests on the same biochip; one specific and one confirmatory as recommended by the World Health Organisation.
The ambition and determination to build a world-beating British diagnostics sector is overdue and right. It offers so many advantages ranging from a healthier and happier population which lives longer to more skilled jobs in a sector which works hand in glove with our world beating academia and NHS. The pandemic has rightly brought the UK’s diagnostics capability into sharp focus, and it is paramount that when we move to a post-Covid world, we take what we have learned from this crisis and build a self-reliant sector fit for the future.
For further information please email randoxpr@randox.com
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We Are Randox | How Kelly Mon became Deputy Testing Coordinator for COVID-19
We Are Randox | How Kelly Mon became Deputy Testing Coordinator for COVID-19
In support of our new £30m COVID-19 laboratories, we are hiring 200 new staff across Engineering, Manufacturing and Science.
For an idea of what it’s like to be part of the COVID-19 testing programme at Randox, we spoke to Deputy Coordinator Manager Kelly Mon.
Kelly spoke to us about what a typical day in COVID-19 testing looks like, the career path she took to her current role, and her advice for a successful job search.
Name: Kelly Mon
Job Title: Deputy Co-Ordinator Manager
Department: COVID-19 Testing
Kelly, what did you study and where?
After secondary school, I studied a BTEC National Diploma in Applied Science (Medical) in Belfast Met in Castlereagh, and then moved on to study Biomedical Science at Ulster University in Coleraine. I later studied part time for an MSc in Stratified Medicine.
Give a brief outline of your career to date
I trained as a Biomedical Scientist in Antrim Area Hospital for one year to gain a recognized certification from the Institute of Biomedical Science. When I graduated I started as a Laboratory Analyst at Randox Clinical Laboratory Services, where I ran health tests on our patented Biochip Technology. After a short time, I became a Clinical Team Leader managing a number of clinical trials for companies and universities. Recently I have been promoted to Deputy Co-Ordinator Manager for our COVID-19 testing programme.
Are there alternative routes into the job?
For a job in Clinical Research you would ideally have a BSc in Biomedical Science, Biochemistry or Life Sciences, and a Diploma in Professional Practice. Alternatively, if you have a degree in another area we have a scheme at Randox that allows graduates the chance to rotate throughout departments, and many good candidates are offered positions at the end. There are also apprenticeships and student placements available.
What does a typical day look like for you?
A typical day in clinical trials usually involves running patient blood or urine samples on Randox Biochips that have been custom-made to suit that particular project. We work to tight deadlines, have regular updates with internal staff and customers, and conduct data analysis and reports. A typical day working on COVID-19 testing involves lots of PPE, and constant communication between a wide range of staff and departments. In my role I oversee our quality control, create and communicate important procedures, and visit the lab to make sure my staff are doing well.
Is this what you always wanted to do?
Whilst I knew that I liked science, I wasn’t sure what job I wanted to do. No one in my circle had ever gone on to study at university so I hadn’t considered it an option. I couldn’t even imagine that I could become a scientist.
What are the best and most challenging aspects of the job?
For me, the best aspect of any job is the people and at Randox I work with a great bunch. I also like the fact that there is career progression for people who put in the work to get it, and that you are trained to perform all tasks, not just one part of the work flow. The most challenging aspect of the job at times is the intensity of the workload, which is why organizational skills and the ability to keep calm under pressure are key in this job.
Why is what you do important?
There is that old saying that your health is your wealth and I’m proud to work for a healthcare company providing high quality health diagnostics. These products are used every day to assist in the detection of a wide range of diseases to provide the earliest possible diagnosis and improved patient outcomes. In my department the clinical trials we manage help to detect biomarkers of disease and determine treatment efficacy, which is important to identify less invasive methods of diagnosis, and more tailored ways to treat each patient.
What advice would you give anyone looking to follow a similar career path?
It’s important in any career to work hard and stick at it. I dropped out of two courses before I started the BTEC Diploma. I could have given up when times were hard, but I stuck with it and here I am sharing what I’ve learnt throughout my career. If you are planning specifically to study Biomedical Science, the advice I would give is to choose a course with a placement. My own course had a one-year placement in an NHS hospital, and the experience in a professional environment that gave me key laboratory skills was invaluable. It also gets you contacts in the industry which is always helpful.
If you weren’t doing this what would you like to do?
I love my job, I love my career and I love the people I work with so honestly, I wouldn’t choose any other career path!
Describe your ideal day off.
My ideal day off work involves pyjamas, junk food and good old Netflix.
And finally, what’s the key to any successful job search?
Sometimes job searching can be tiresome and after a while you start to apply without properly researching, but the key to any successful job search is preparation. Start by giving your CV an update and get someone – perhaps your university careers team, or a friend or family member – to proof-read it. Or, if you don’t have any other help, you can begin by searching CV templates on the internet. Personally I would advise that you include some interesting hobbies to make your application stand out. You would be surprised how things seemingly unrelated to a particular job will keep you in the recruiter’s mind. Then come up with some possible questions and think of the answers you might give before you go for interview.
We are delighted to have Kelly with us at Randox as part of our COVID-19 testing programme.
For current vacancies at Randox please visit careers.randox.com
For more We Are Randox stories about our amazing colleagues, make sure to follow us on Facebook, Instagram and Twitter and follow the hashtag #WeAreRandox.
For further information please email recruitment@randox.com or phone 028 9442 2413.
Want to know more?
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COVID-19 Testing: PCR (Diagnostic) vs Antibody
18 June 2020
COVID-19 Testing: PCR (Diagnostic) vs Antibody
The advice from the World Health Organisation in relation to the COVID-19 pandemic has been simple; Test. Test. Test.
But what are the different types of COVID-19 tests and what are they used for?
Diagnostic (PCR) Testing
This type of testing detects SARS-CoV-2 (the virus that causes COVID-19) within the body and will tell you if you currently have COVID-19. PCR tests cannot tell you if you have had past infection.
Sample collection for a PCR test can vary, though it is usually in the form of a swab, which will gather an individual’s nasopharyngeal (nose and throat) secretions.
PCR tests for COVID-19 all use methods that detect a specific part of the viral genome – for example Viral RNA or Antigen.
A sample is prepared by extracting the chosen section of the genome, and then PCR (Polyamerase Chain Reaction) techniques are used to amplify (replicate) the genome section, ready for detection.
Viral RNA Tests
This type of test detects the RNA (Ribonucleic acid) contained within the SARS-CoV-2 virus.
It is this type of test, for RNA, that is recommended by The World Health Organisation for COVID-19 diagnosis.
Antigen Tests
Antigens are molecular structures on the surface of viruses that are recognized by the immune system and are capable of triggering an immune response.
Antigen tests detect the presence of the SARS-CoV-2 virus by looking for the antigen on the surface of the virus.
Randox COVID-19 Test
The Randox COVID-19 test, as recommended by the World Health Organisation, detects the RNA contained within the SARS-CoV-2 virus.
After sample extraction and amplification, the virus is detected on our patented Randox Biochip Technology platform.
The Randox Biochip, which can run multiple tests simultaneously, performs two tests for COVID-19 – one specific and one confirmatory – as recommended by the WHO. This delivers extra assurance of the correct diagnosis and avoids the need to repeat the test.
Antibody (Serology) Tests
Antibody (also known as serology) tests, are usually performed on a patient blood sample, and look for antibodies (a type of protein) that may have been developed by the patient’s immune system to fight off disease.
If present, antibodies may provide a degree of immunity for the patient against COVID-19 in the future.
However, there is still much unknown about the body’s antibody response to COVID-19, including;
- Whether all patients who have been infected with SARS-CoV-2 will generate antibodies (recent studies and news reports indicate that this isn’t the case. Click here for an example.)
- Whether those who have had more severe symptoms as a result of COVID-19 will produce more antibodies than those who had mild symptoms, or were asymptomatic.
- If antibodies from other coronaviruses previously experienced by the patient may be enough to fight off the virus, therefore eliminating the need for COVID-19 specific antibodies.
- How long any COVID-19 specific antibody response will last for.
- How much future immunity is provided by COVID-19 antibodies. Will it prevent the patient from being infected, or will future infection just be less severe?
If antibodies for the SARS-CoV-2 virus are present this can give an indication that the patient has been previously infected with COVID-19. Antibody tests do not confirm the real-time presence of the virus in your system.
For example, a negative antibody result does not necessarily mean the body has not been exposed to the SARS-CoV-2 virus. It could in fact, be currently infected, but has not yet generated antibodies. A diagnostic test will confirm current presence of the virus.
Therefore, it is recommended that antibody tests are used in tandem with a diagnostic test to determine a complete overview of the patient’s COVID-19 status.
Randox Health currently offers both diagnostic testing and antibody testing for SARS-CoV-2 (COVID-19).
A combination of diagnostic and antibody testing is available for individual purchase, or as part of our ‘Back to Business’ COVID-19 testing service, for staff screening.
Visit Randox Health to find out more.
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COVID-19 Laboratory Tools for Disease Management
17 June 2020
COVID-19 – Laboratory Tools for Disease Management
In addition to tests for the detection of SARS-CoV-2, the virus that causes COVID-19, laboratory diagnostics play a pivotal role in patient management, risk stratification, monitoring of disease progression, associated complications and response to treatment.
Randox offers a comprehensive range of laboratory solutions including; diagnostics reagents, revolutionary Biochip technology and quality control designed to provide clinicians with valuable insights into disease severity ultimately helping to improve patient care.
Patients with comorbidities such as diabetes mellitus, cardiovascular disease (CVD) and chronic kidney disease (CKD) are particularly susceptible to COVID-19 infection and are at greater risk of developing severe illness. The Randox portfolio may also be used to diagnose and monitor such at risk patients with underlying health concerns.
Biochemistry Reagents
Our extensive test menu comprises 113 assays, including many unique tests and a range of biomarkers designed to assist laboratories when screening for a variety of COVID-19 related health issues.
Randox Reagents are internationally recognised as being of the highest quality; producing accurate and precise results. Applications are available detailing instrument-specific settings for the majority of clinical chemistry analysers.
Elevated markers of inflammation and infection such as CRP may indicate severe viral infection. CRP is elevated in up to 86% of COVID-19 patients who are admitted to hospital. Testing for CRP is useful in assessing prognosis, and when monitoring improvement. It is recommended that CRP is measured at baseline and then at intervals, a sudden increase in levels will prompt surveillance for secondary infection or other cause of deterioration.
As an acute phase reactant, Ferritin levels increase in response to inflammation. High levels have been identified in approximately 60% of individuals hospitalised as a result of COVID-19 infection. In critically ill patients, elevated Ferritin levels may be indicative of a cytokine storm and secondary haemophagocytic lymphohistiocytosis, a hyperinflammatory syndrome associated with organ failure.
Liver Function Tests (Albumin, ALT, AST, Bilirubin)
Patients with COVID-19 may be at higher risk of liver injury or impairment of liver function. Liver function markers such as ALT, AST and Bilirubin are notably higher in more severe infections, decreased albumin levels have also been documented in severe cases. Drug induced liver injury as a result of COVID-19 treatment should not be ignored and should be monitored.
Renal Function Tests (Creatinine, Cystatin C)
Emerging evidence suggests that SARS-CoV-2 may directly affect kidney function, as such COVID-19 patients should be assessed for Acute Kidney Injury (AKI) on admission to hospital and monitored throughout their stay. AKI can lead to worse outcomes for patients.
LDH levels may be a convenient marker for the identification of COVID-19 patients at higher risk of developing severe respiratory failure. It is well documented that high LDH levels are indicative of haematological malignancy and acute lung injury. LDH levels might therefore reflect tissue necrosis related to immune hyperactivity and thus are related to poor clinical outcomes in individuals with COVID-19.
Chloroquine has been investigated as a potential treatment for COVID-19, the anti-malaria drug however could have devastating consequences for those with a G6PDH deficiency. G6PDH deficiency is a genetic disorder affecting the red blood cells, causing them to break down prematurely. The most common complication of deficiency is haemolytic anaemia. An estimated 400 million people globally have G6PDH deficiency, it is most common in certain parts of Africa, Asia, the Mediterranean and Middle East.
Randox Biochip Solutions
Randox Biochip technology is extremely versatile with applications in not only the diagnosis of COVID-19 but also the identification of individuals at risk of developing more severe illness.
Unique to Randox, Biochip technology is capable of simultaneous detection of a panel of related disease markers. An extensive range of Biochip panels are available, each optimised to provide the best performance.
Cytokines play a vital role in the immune system and are known to be involved in the body’s response to a variety of inflammatory and infectious diseases. The over stimulation of these cytokines in response to infection is referred to as a ‘cytokine storm’ and strongly correlates with poor disease outcomes. Cytokine storms are a common complication of SARS-CoV-2 infection triggering viral sepsis, where viral replication and excessive, uncontrolled systemic inflammation may lead to pneumonitis, Acute Respiratory Distress Syndrome (ARDS), respiratory failure, shock, multiple organ failure, secondary bacterial pneumonia, and potentially death. Cytokines such as IL-6 appear to be elevated in patients with more severe illness and may be used to monitor response to treatment as levels decrease as the condition improves.
Quality Control Solutions
Randox offer a range of Quality control and External Quality Assessment (EQA) solutions designed to ensure the accuracy and reliability of patient testing.
Decreased blood counts have been frequently identified in COVID-19 patients and may be indicative of a decreased immunological response to the virus, bacterial infection or consumption.
Blood Gas tests are used to help diagnose and monitor critically ill patients in intensive care units (ICU) and emergency departments. Blood Gas testing continues to play a critical role in the management of COVID-19 patients providing an indication of a patient’s oxygenation levels. Monitoring of these levels will enable healthcare professionals to make ventilator adjustments if required.
Increased levels of cardiac markers including Troponin and CK-MB may be associated with a higher mortality rate in COVID-19 patients.
Patients with severe COVID-19 infection are more likely to have coagulopathy, a condition in which the bloods ability to form clots is impaired. Activation of blood coagulation factors such as Prothrombin Time (PT) and D-dimer are significant predictors of disease severity and mortality.
Procalcitonin is an acute phase reactant released by most tissues during inflammation and is particularly associated with bacterial infection. Although it is not usually elevated in viral infections such as SARS-CoV-2 levels may increase as a result of severe systemic inflammation. It may also be used to help detect secondary infections.
For further information about any of the above Laboratory Tools for COVID-19 Disease Management please email marketing@randox.com
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We Are Randox | How Sean Mills became Production Supervisor at Randox
We Are Randox | How Sean Mills became Freeze Dry Production Supervisor at Randox
In support of our new £30m COVID-19 laboratories, we are hiring 200 new staff across Engineering, Manufacturing and Science.
For an idea of what it’s like to work in Manufacturing at Randox, we spoke to Freeze Dry Production Supervisor Sean Mills.
Sean spoke to us about what his job entails, the skills required for the role, and what advice he would give someone on their first day of a new job.
Name: Sean Mills
Job Title: Supervisor
Department: Freeze Dry Production
Sean, what route did you take to get your job?
At school my favorite subjects were Biology and Physical Education, and though I completed my A-levels, I turned down the opportunity to go to the university I had selected. I just knew that going to university was not for me. I had previous work experience working in a laboratory, having volunteered in the Belfast City Hospital labs, as well as some other manufacturing experience from various summer jobs, so I applied for a Manufacturing Operative job with Randox. I started with the company on 3rd November 2008 and have progressed throughout the department. I worked my way up to Laboratory Technician, then Lead Laboratory Technician, and now Departmental Supervisor.
Can you give us a quick summary of what your job entails?
My main responsibility is the day-to-day running of the Randox Freeze Dry Production team, which starts every day with a morning meeting to go over our schedule. I review our workload, determine what sites we will be working at, and delegate tasks to different members of the team. I also check if there were any issues from the previous day that we need to look at. As Supervisor I liaise with the Planning Team to manage our work to meet production deadlines, and with the Purchasing and Stock departments to order materials that we need to complete our work. I like to be practical and hands-on so in addition to my administrative duties I also do manual work like loading and unloading freeze driers.
Is this what you always wanted to do?
When I was younger I was unsure what I wanted to do for full time employment but this is my 12th year as part of the Randox family and I am so glad I chose to work here. It has been a fantastic environment in a dynamic role that continues to challenge me every year. In February this year I was really proud to be named Randox Employee of the Year 2020.
Were there any particular essential qualifications or experience needed?
For the job I originally applied for there were no specific requirements other than a GCSE in Maths and English. Given the work we do, I would definitely say that an understanding of Maths and English are important.
Are there alternative routes into the job?
One of the great things about Randox is that you can change roles internally if you want to try a new discipline or have a new experience. As such there is a real mix of backgrounds across all teams in the company. Some people join us after university or after working for other companies, and others like myself begin their careers here and then progress within their department.
What are the main personal skills your job requires?
Organisational and numerical skills, as well as excellent communication and good time management, are definitely essential in my role. The ability to follow health and safety procedures and work off your own initiative are also key.
What are the best and most challenging aspects of the job?
Having worked within manufacturing for over 10 years now I am no stranger to a lot of hard work in order to meet a deadline. These pressure situations are something I enjoy as they allow you to think of ways to improve manufacturing processes. I am lucky I work with a fantastic team and have a great manager who has also worked his way up in the department. He is a great mentor.
Why is what you do important?
My team are responsible for manufacturing the highest quality product to facilitate patient diagnosis. My own role specifically is important to keep the team motivated and ensure everything is in place to allow them to complete their job. I am here to train new staff, help problem solve, and use my experience to support my team when they need it.
If you weren’t doing this what would you like to do?
If I wasn’t working in Manufacturing I would like to work in the Police or Fire Service.
What is the one piece of advice you would give to yourself on your first day?
To anyone about to begin their first day in a new job I would give reassurance that they don’t need to be nervous. I would also encourage asking as many questions as possible until you are 100 percent sure what you’re doing and what’s expected from you. With any job there is always something new to learn and people you can learn from. No one knows everything, and everyone needs a little help now and again.
Describe your ideal day off.
On my ideal day off I would get up early to play a round of golf or go to the gym. Then I would spend the day with my partner, enjoy a nice meal and end the day by watching a movie.
And finally, what’s the key to any successful job search?
I have been happily working at Randox for almost 12 years, so I think that means my last job search was a successful one! My advice would be to apply for a job that excites or interests you.
We are delighted to have Sean with us at Randox as part of our hard-working manufacturing team.
For current vacancies at Randox please visit careers.randox.com
For more We Are Randox stories about our amazing colleagues, make sure to follow us on Facebook, Instagram and Twitter and follow the hashtag #WeAreRandox.
For further information please email recruitment@randox.com or phone 028 9442 2413.
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Cytokine testing for COVID-19 risk stratification and treatment monitoring
11 June 2020
Cytokine testing for COVID-19 risk stratification and treatment monitoring
On Biomedical Science Day 2020, an innovative method of monitoring treatment efficacy and recovery of COVID-19 has been unveiled by global diagnostics company Randox Laboratories.
The test, which looks for the presence of cytokines (a type of small protein) is performed on Randox’s patented Biochip Technology, which can simultaneously detect multiple analytes from a single patient sample.
Cytokines play a vital role in the immune system and are known to be involved in the body’s response to a variety of inflammatory and infectious disease, such as COVID-19.
Lynsey Adams, Randox Marketing Manager, commented;
“Cytokine storms, which are the overstimulation of cytokines in response to infection, are a common complication of severe cases of COVID-19, and can trigger excessive, uncontrolled systemic inflammation.
“The monitoring of cytokine proteins therefore offers a unique opportunity to identify patients who, as a result of this viral sepsis, are at risk of poor disease outcomes including pneumonitis, Acute Respiratory Distress Syndrome, respiratory failure, shock, or even organ failure.
“Treatment for any infection, COVID-19 included, is most effective when administered at an early stage, and so the detection of cytokine storms within COVID-19 patients could provide vitally important information that will direct the appropriate patient care pathway and facilitate improved patient outcomes.”
The comprehensive cytokine testing menu from Randox comprises of 26 different cytokines, across four different biochip panels.
Designed to make cost, time and resource savings for a range of diagnostic laboratories, Randox Cytokine Biochips can detect up to 12 cytokines and growth factors from a single patient sample.
Lynsey continued;
“The multiplex capabilities of the Randox Biochip will provide clinicians with a more comprehensive picture of the patient’s condition.
“Compatible with our Evidence and Evidence Investigator analysers, which are capable of processing 2960 and 2376 tests per hour respectively, Randox Cytokine Biochip panels offer a comprehensive testing method for these proteins which play such a central role in the immune system.”
In addition to COVID-19 risk stratification, cytokine testing has also been linked to monitoring for allergies, vascular diseases, cancer, and a range of autoimmune diseases.
Key Benefits of Randox Cytokine Testing
- Simultaneous detection of up to 12 cytokines and growth factors from a single patient sample
- Fully automated and semi-automated testing platforms available to suit all laboratory throughputs
- Comprehensive test menu comprising 26 cytokines, cytokine receptors and growth factors
- Suitable for use with serum and plasma samples
- Excellent analytical performance
- Availability of complementary quality controls for a complete testing package
For more info please visit www.randox.com/cytokine-testing-solutions/, email marketing@randox.com or phone 028 9442 2413
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We Are Randox | How Ciara Taylor became R&D Team Leader at Randox
We Are Randox | How Ciara Taylor became Clinical Immunoassay R&D Team Leader at Randox
In support of our new £30m COVID-19 laboratories, we are hiring 200 new staff across Engineering, Manufacturing and Science.
For an idea of what it’s like to be a scientist at Randox, we spoke to R&D Team Leader Ciara Taylor.
Ciara spoke to us about the route she took to her current role, what advice she would give someone following a similar career path, and what makes her job so important.
Name: Ciara Taylor
Job Title: R&D Team Leader
Department: Clinical Immunoassay R&D
Ciara, can you give us a quick summary of what your job entails?
Our team works on the research and development of new clinical diagnostic tests for a variety of common health conditions, such as heart disease. We carefully design and execute laboratory experiments to ensure our tests perform at an exceptionally high level for hospitals and laboratories around the world.
What did you study and where?
I studied a four-year integrated Chemical Engineering Masters degree at Queen’s University Belfast. It was an ideal choice for me as it encompassed areas of the subjects I had enjoyed at school; Chemistry, Physics, Biology and Maths. I gained a lot of experience in research during my final year industrial project.
Give a brief outline of your career to date
I finished my university degree in 2016. I worked for an Engineering consultancy firm for 6 months, and then spent some time travelling before joining Randox in October 2017. In my first year I spent time learning about the science behind immunoassay development and how to apply to our research work. At the end of 2018, I was promoted to Research and Development (R&D) Team Leader, giving me more responsibility over the training of staff, and the progress of new projects, from initial concept and feasibility to product validation. I have also had the opportunity to travel and represent the company in conferences, events and career days.
Is this what you always wanted to do?
When I was younger I honestly had no idea what my ideal job would be. I simply knew that I wanted a dynamic role that involved working with people on challenging and interesting projects, which is exactly what I have here at Randox. I love the variety and opportunity that a global company like Randox offers as we are always trying to evolve and keep up with the latest industry demand. Currently every department is working together to process large-scale testing for COVID-19, as part of the government’s national testing programme.
Were there any particular essential qualifications or experience needed?
We have people of varying degree backgrounds in our team including Chemistry, Chemical Engineering, Biochemistry, Biomedical, Biological or Pharmaceutical Sciences. Experience in a similar R&D capacity is also helpful, though we offer full training to those who may have little experience specifically in diagnostics, but who possess a general science background.
Are there alternative routes into the job?
Whilst I joined Randox as a graduate R&D scientist following university, there are other routes available. Some of my colleagues began their careers by doing a placement year with Randox or by taking part in our Graduate Programme, in which graduates rotate across different areas of the business to find a job best suited to their skills and interests. Also available as an option is the Randox APEX scheme, which gives first year university students a summer and a third-year placement, and a job offer upon graduating. Naturally we also have a lot of PhD graduates join R&D, as they are ideal candidates for conducting research. Another route, if you don’t have the A-Levels for a university degree, is to go to a Technical College and gain an equivalent qualification in a science discipline. This could lead to a placement opportunity and later job with Randox.
What are the best and most challenging aspects of the job?
The best part of working in Randox is the people you work with. We work very collaboratively across different departments, and our staff come from a wide variety of backgrounds, so I am constantly learning from everyone around me and bouncing ideas off different people with different skillsets.
The most challenging aspect is the same in every R&D role – sometimes the initial feasibility experiments just don’t give the results you had expected. The rewarding part lies in solving the problem and making a breakthrough in your research project.
Why is what you do important?
The development of clinical diagnostic tests has a direct impact on the quality of healthcare that people receive around the world. It is rewarding to be part of a global company that is trying to improve people’s lives by providing a more personalised diagnosis using the tests we develop. As a company, Randox is continually investing money into the research of novel clinical biomarkers and testing platforms, showing its commitment to the improvement of diagnostics and ultimately, patient outcomes.
What advice would you give anyone looking to follow a similar career path?
If you are interested in R&D, keep your options and searches open. I didn’t know how much I would enjoy clinical R&D until I started at Randox. It makes a difference when you are genuinely interested and take pleasure in the work you do. Previous lab experience is ideal, so I would recommend trying to do a placement or getting some relevant work experience, especially if your degree doesn’t include much practical lab work.
If you weren’t working in Clinical Immunoassay R&D what would you like to do?
I would still love to be in a research role, perhaps in renewable or clean energy sources.
Describe your ideal day off
My ideal day off involves exercise or eating! I would go for a swim, yoga or a long walk, and then go out for dinner. I love trying new restaurants.
We are delighted to have Ciara with us at Randox as part of our incredibly talented R&D team.
For current vacancies at Randox please visit careers.randox.com
For more We Are Randox stories about our amazing colleagues, make sure to follow us on Facebook, Instagram and Twitter and follow the hashtag #WeAreRandox.
For further information please email recruitment@randox.com or phone 028 9442 2413.
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CE marking granted to Quality Control for newborn infectious disease tests
08 June 2020
CE marking granted to Quality Control for newborn infectious disease tests
ToRCH Quality Controls to support the accuracy and reliability of infectious disease testing in newborns, have been granted CE marking.
The controls for ToRCH, which is a blood test screening to detect infectious diseases including toxoplasmosis, rubella, cytomegalovirus, and herpes simplex, are available from global diagnostics company Randox Laboratories, and are used to ensure accurate ToRCH test and system performance.
Manufactured from human plasma, each control is designed to react to the test system in the same manner as the patient sample, helping laboratories to meet ISO 15189:2012 for quality and competence.
Lynsey Adams, Randox Quality Control Manager, commented;
“The CE marking of the ToRCH controls from Randox will be a game-changer for clinicians and patients alike, by facilitating early, accurate and comprehensive diagnoses of infectious diseases in newborns, that allow for the best possible patient outcomes.
“Ultimately, these ToRCH controls will guarantee quality assurance in laboratories performing ToRCH screening in newborns.”
Randox ToRCH Controls are also multi-analyte and therefore, testing can be consolidated to just a small number of vials to save laboratories valuable space and time.
In addition to ToRCH, Randox Infectious Disease Quality Controls also include quality control material for Lyme Disease, Epstein-Barr virus, HIV, Hepatitis A virus, Human T-lymphotropic virus, Cytomegalovirus, and Varicella zoster virus (Chickenpox or Shingles).
Lynsey continued;
“Unlike analyser-specific tests, these controls can be used across a wide range of laboratory technologies, and complement our already existing RIQAS Serology EQA programmes to provide laboratories with a complete QC solution from a single supplier.
“With a working stability of 60 days at 2°c to 8°c which keeps waste and costs to a minimum, Randox Infectious Disease Controls are set to revolutionise serology testing and provide reliable, accurate results time and time again.”
Randox Infectious Disease Controls are ideal for microbiology and virology laboratories, blood banks, public health laboratories or clinical laboratories performing serology testing.
Key benefits of the Randox Infectious Disease Controls;
- User-friendly – all samples are provided in a liquid, ready-to-use format
- Commutable – manufactured from human plasma, each control reacts to the test system in the same manner as a patient sample
- Versatility – designed to deliver an independent, unbiased assessment of performance with any immunoassay instrument
- Stability – working stability of 60 days ensures waste and costs are kept to a minimum
- Multi-marker – helps reduce the number of individual controls required
- Clinical relevance – designed to challenge clinically-relevant levels, samples will ensure accurate and reliable instrument performance
For more information visit https://www.randox.com/torch-controls/
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We Are Randox | How James Davidson became a Mechanical Design Engineer at Randox
We Are Randox | How James Davidson became a Mechanical Design Engineer at Randox
At the beginning of April we announced we are recruiting mechanical, electrical and manufacturing engineers to enhance our capacity for COVID-19 testing. The engineers will be involved in the fast-tracked development of specialist molecular analysers used to detect the presence of COVID-19.
For an idea of what it’s like to work in engineering at Randox, we spoke to Mechanical Design Engineer James Davidson.
James spoke to us about the route he took to his current role, the best and most challenging things about his job, and how he likes to spend his well-deserved time off.
Name: James Davidson
Job Title: Mechanical Design Engineer and Project Coordinator
Department: Engineering
James, can you give us a quick summary of what your job entails?
My main responsibilities are designing new medical testing analysers, updating and developing our existing machines and conducting troubleshooting to make sure that they are performing correctly. I also train new and existing staff on Randox technologies.
What was your favourite subject at school?
I really enjoyed Maths at school, for the challenge of being able to solve a logical problem and get to the correct conclusion by the end of your working out.
What was the route you took into your job?
My A-levels didn’t go to plan at school and I found myself in a difficult situation where I didn’t have the grades to go to university as I had planned.
I subsequently went along to an information evening at the Northern Regional College in Ballymena where I found out about the Higher National Diploma in Manufacturing Engineering, which really appealed to me and suited my interests. I knew straight away that it’s what I wanted to do so I started the course a week after that and really enjoyed it. Completion of the HND opened the door to enroll in a degree in Mechanical Engineering at the University of Ulster in Jordanstown, where I graduated with a 2:1 in 2012. I secured a placement at Randox in 2010 as part of this degree course which ultimately led me to the role that I am currently in.
Give a brief outline of your career to date
The year-long placement I did at Randox taught me a lot. I enjoyed it so much that I came back to Randox after my degree and have been here since! Throughout my time in Randox I have worked on different projects that have each been at different design stages – from concept right through to market release. I was promoted to Project Coordinator in 2016 and placed in charge of a small team of mechanical engineers. In this role I plan new work for each member of the team, review designs and provide assistance if required. I love being part of the Engineering team at Randox. It’s a really creative environment and we all work collaboratively together – bouncing ideas off each other and supporting each other when needed.
Is this what you always wanted to do?
I have always had an interest in how things work so a career in engineering was a natural progression for me. The world is constantly changing with new innovations and solutions to better people’s lives and I’m happy to be involved in an area of engineering that is bettering such a key part of people’s lives – their health.
Are there alternative routes into the job?
There are several potential routes to becoming a mechanical design engineer. Whilst I didn’t take the traditional route to become a design engineer – completing A-levels and then going to university – this would be the most common option. Alternatively, you can do what I did and study an HND before then getting a degree. Experienced engineers with a Higher National Certificate/Diploma could also be considered for the role.
What are the main personal skills your job requires?
For a mechanical design engineer the main essential skills would be an ability to work as part of a team, the ability to problem solve, knowledge of manufacturing processes and a flair for design. The ability to work under pressure and a high attention to detail are useful skills to have as well.
What does a typical day look like for you?
It might sound cliché, but every day is different! Up until earlier this year I was part of a product development team who design machines for a range of clinical conditions. More recently I have been involved in the design and development of a specialist COVID-19 testing system that will dramatically increase our capacity to process samples.
What are the best and most challenging aspects of the job?
It is simultaneously gratifying and challenging to experience the full cycle of project development from start through to finish. It requires quite a lot of patience.
Why is what you do important?
By guaranteeing that diagnostic machines are performing correctly, I am essentially making sure that patients across the globe are getting the correct medical diagnosis and follow-up treatment. These machines are life-saving devices.
If you weren’t a Mechanical Design Engineer what would you like to do?
My dad and brother own a garage so I think I would be working as a mechanic with them. It would harness the same skills and interests as my current role! I have also considered the possibility of being a teacher.
Describe your ideal day off.
I enjoy water skiing so on my days off, if the weather is good, I like to go out on the water. It’s a great way to blow off some steam.
And finally, what’s the key to any successful job search?
My advice to anyone currently looking for a job would be to find something with a lot of variety. You don’t want to be doing the same thing over and over again and you need to keep things interesting. I’m proud to say that my job at Randox has held my interest for the best part of a decade!
We are delighted to have James with us at Randox as part of our incredibly talented engineering team.
For current vacancies at Randox please visit careers.randox.com
For more We Are Randox stories about our amazing colleagues, make sure to follow us on Facebook, Instagram and Twitter and follow the hashtag #WeAreRandox.
For further information please email recruitment@randox.com or phone 028 9442 2413.
Want to know more?
Contact us or visit our Randox Careers
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Randox announces its £30m investment in specialised COVID-19 testing lab
Randox invests £30m and 200 new jobs in specialised COVID-19 testing lab
As part of efforts to enhance its national testing capacity, global diagnostics company Randox has announced an investment of £30m in a new specialised COVID-19 testing hub.
The healthcare firm, which is currently conducting COVID-19 tests as part of the national testing programme, announced its investment in the new facilities based at the Randox Science Park in Antrim, Northern Ireland, during a visit yesterday by the Secretary of State for Northern Ireland, The Rt Hon Brandon Lewis CBE.
The specialised laboratory, the development of which was fast-tracked over the space of four weeks, is the first step in a wider diagnostics investment programme from Randox.
Dr Peter FitzGerald, Managing Director of Randox Laboratories, commented;
“The national testing programme, as a collaborative effort by government and various partners within industry, has increased testing capacity at an unparalleled speed – by installing a network of drive-through testing centres, introducing home testing kits, and now, opening this specialised lab at the Randox Science Park in Northern Ireland.
“An incredible amount of work has gone into making this cutting-edge testing facility a reality in a relatively short space of time, as we know that effective testing is the most effective way to both save lives and promote a timely return to a more normal society.”
The opening of the new laboratory at the Randox Science Park follows the company’s announcement that it is recruiting new staff across Science, Engineering and Manufacturing in support of its role within the national testing programme.
The 200 new positions will be involved in the testing of potential COVID-19 samples, as well as the construction of 200 new state-of-the-art diagnostic analysers which will significantly increase Randox’s capacity for COVID-19 testing.
Dr FitzGerald continued;
“Now that we have in place the infrastructure and laboratory space required to enhance our testing capacity, we look forward to implementing the next step in our COVID-19 investment programme.
“By accelerating the build schedule for new specialised equipment, and hiring 200 associated workers across Science, Engineering and Manufacturing we will further enhance the government’s national testing scheme, as well as facilitate testing more broadly across the general populace.”
Secretary of State Brandon Lewis MP welcomed the new investment saying:
“I was impressed during my visit with the dedication of staff and the top-class facilities at Randox. This investment will help support the UK’s nationwide effort to fight the coronavirus and ultimately save lives.”
Dr FitzGerald concluded;
“I would also like to take this opportunity to pay tribute to all my colleagues at Randox who continue to work assiduously to process such a high volume of tests in a timely manner.
“I know I speak on behalf of everyone when I say we appreciate all your hard work and the vital role you play in the practical application of COVID-19 testing.”
For further information please email randoxpr@randox.com
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