We Are Randox | QUB and Ulster University Students Take The Top Spots in the Randox Placement Awards 2019

We Are Randox | QUB and Ulster University Students Take The Top Spots in the Randox Placement Awards 2019

A Queen’s University Belfast student has won the top spot in global healthcare diagnostics company Randox Laboratories’ annual Student Placement Awards.

Pearce Allingham from Andersonstown, who is studying Medicinal Chemistry, was not only placed first in the Science category but was also crowned Best Overall Placement Student.

Since September 2018, Pearce had been working alongside the scientific team in the New Technology Evaluation department, taking part in the development of Randox’s newest and most classified innovations.

Speaking at the awards ceremony at Randox Laboratories HQ in Crumlin on Friday 14th June 2019, Pearce commented,

“I’m so pleased to have won this award. I couldn’t recommend a placement at Randox highly enough and it has allowed me to see what I’m capable of when I apply myself to a field I’m passionate about. From day one I was made to feel like a scientist within the team – not just a placement student – and it’s amazing that some of my contributions are helping to advance Randox’s diagnostic capabilities further. I look forward to applying my new knowledge and skills in final year and to forging a career in research – maybe even back here at Randox.”

Randox Laboratories welcomes over 60 placement students through its doors each year across Science, Engineering and Business-related disciplines, including Sales and Marketing. The company is keen to continue to maintain its reputation as a key placement provider in Northern Ireland, as explained by Linda Magee, Operations Director at Randox Laboratories.

Linda commented;

“We host many high calibre placement students at Randox each year and the Randox Placement Awards is the pinnacle in highlighting the fantastic contribution that these students make. Pearce, in particular, impressed us with his work ethic and initiative in one of Randox’s most cutting-edge R&D teams. Gaining industry experience is vital for young people and that is why we pride ourselves on the range of placement opportunities we provide here, especially through the Randox APEX programme which offers students a paid summer placement between first and second year, a paid placement year in third year and, finally, a graduate position on completion of their degree with a 2:1 classification. It really is the complete career package for any aspiring student.”

David Boyd, a QUB Engineering student from Belfast, won in the Engineering category of the Randox Placement Awards while Andrew Wilson, an Ulster University student from Bangor, was placed first in the Business category.

David Boyd, Engineering Placement Award winner, commented,

“As part of the Engineering team, the opportunities I’ve been given here have been second-to-none and I look forward to completing my Master’s degree in Mechanical Engineering. I used to think I would go on to work in the energy sector with renewables and nuclear but my time in Randox has shown me a different industry which I would love to return to.”

Andrew Wilson, Business Placement Award winner, also said,

“Being given the same responsibilities as the rest of your colleagues is a great way to learn quickly as you get immersed in live projects and real business. One of the most interesting aspects for me was the opportunity to travel to Hamburg and Chicago for customer visits and conferences. Dealing with different departments such as manufacturing, finance and logistics, along with my own sales and marketing team, has given me an insight in to the workings of an international company which has been an invaluable experience.”

Randox Placement Awards 2019 results

Business category

1 Andrew Wilson (Marketing, Randox Food Diagnostics), an Ulster University student from Bangor

2 Kathryn Wilson (Sales, Randox Biosciences), an Aberystwyth University student from Larne

3 Adam Donnelly – (Marketing, Randox Corporate), an Ulster University student from Bellaghy

Science category

1 Pearce Allingham (Chemistry), a Queen’s University Belfast student from Andersonstown

2 Rachel McCloy (Biotechnology), a Liverpool John Moore’s University student from Ballymena

3 Thomas Smith-Zaitlik (Molecular), a Nottingham Trent University student from Henley-on-Thames.

Engineering category

1 David Boyd (Engineering Design, Mechanical), a Queen’s University Belfast student from Belfast

2 Reuben Cotton (Engineering Design, Mechanical), an Ulster University student from Lisburn

3 Niall Devlin (Engineering Design, Software)

Overall Randox Placement Awards winner: Pearce Allingham

For further information please contact the Randox PR team by emailing randoxpr@randox.com or phoning 028 9442 2413

 

 

 

 

 

 

 

 

 

 

 

 


Egypt Introduces New Drug Testing Policy

In early May 2019, over 550 state employees in Egypt were referred to the Egyptian public prosecution office after being forced to take a drug test under a new law.

The Ministry of Social Solidarity announced on May 5th that 15,877 state employees had recently been drug tested, and that 555 had been referred to the Administrative Prosecution Authority (APA) for testing positive for illegal drugs.

The sudden crackdown on drug users follows the government in Egypt approving a bill in March that authorised the required drug testing of all state employees from ministerial to the local level. Alongside members of the civil service, employees working for public transportation, hospitals, and other state-run institutions must also be drug tested. Anyone who refuses to be drug tested will have their employment terminated.

The new law was brought in with explicit support from Prime Minister Moustafa Madbouli, following a deadly train crash in Cairo after which the train driver tested positive for drug use.

Egyptian law does not specify the punishment for someone who tests positive for drug use, but the director of Egypt’s Fund for Drug Control and Treatment – Amr Osman – has warned that any state bus or rail drivers testing positive for drug use face imprisonment for at least two years, and a fine of 10,000 Egyptian pounds ($582).

University students and employees will also be subject to mandatory drug testing, the education minister has announced. In this case, people who test positive will be offered “treatment” and will be sacked or expelled from the university if they refuse to comply.

Randox Toxicology offer the Evidence MultiSTAT, a fully automated immunoanalyser that, utilising Biochip Array Technology (BAT), enables on-site simultaneous detection of up to 21 drugs of abuse from a single sample. The Evidence MultiSTAT requires only a small sample volume and can generate results in under 20 minutes. The process from sample entry to results is completed in only 3 simple steps, with minimal room for human error. The MultiSTAT is designed to make set-up and analysis as quick, simple and reliable as possible.

To find out more about the Evidence MultiSTAT and Biochip Array Technology, visit www.randoxtoxicology.com or email us at info@randoxtoxicology.com

 

 

 

 

 

 

 

 

 

 

 

 

 


Randox Biosciences on Familial Hypercholesterolemia (FH)

What is Familial Hypercholesterolemia?

Familial Hypercholesterolemia (FH) is a genetic condition which is passed down from the parents’ genes. The British Heart Foundation has highlighted that FH is caused by a genetic mutation which means the liver is unable to remove excess ‘bad’ cholesterol (LDL), therefore, the LDL level in the blood remains high.2 Someone who suffers with FH would have high cholesterol from birth which can cause other health issues including heart and circulatory disease.

Heart UK states that more than 260,000 people in the UK may have FH. However, less than 10% of this number have been diagnosed and therefore, may not be aware of their condition.3 However, to date there are no clear symptoms if someone has FH until it is considered too late.

Familial Hypercholesterolemia (FH) symptoms

  • Swollen tendons/fatty lumps on the knuckles of your hands, at the back of your ankles and knees
  • Cholesterol deposits around the eye-lids (looks like pale and yellowish patches)
  • Grey-white cholesterol deposits around the corneas

If untreated, about 50% of men and 30% of women with FH will develop coronary heart disease by the time they are 55. More worryingly, on average in the UK, one person a day with FH has a heart attack. About a third of people don’t survive their first heart attack, and many who do survive will have damaged hearts.

The good news is that a 2008 study part-funded by the BHF found that people with FH who are diagnosed and treated before they develop heart disease generally live as long as people who don’t have FH. That’s why it is vitally important to get diagnosed as early as possible.

How Randox Biosciences can help

Randox Biosciences offers the Familial Hypercholesterolemia (FH) Arrays I & II to help encourage early diagnosis with rapid turnaround time. This allows results to be reported within days compared with NHS waiting lists which can be substantially longer.

Our two arrays are rapid, simple and accurate which enables the simultaneous detection of 40 FH-causing mutations (20 mutations per array) within the LDLR, ApoB and PCSK9 genes.

The mutational status can be determined rapidly from a single test, with a reduced need for confirmatory testing. Genetic analysis for FH mutations also allows for more accurate diagnosis compared to lipid profiling.

Familial Hypercholesterolemia (FH) Arrays I & II:

LDLR – 38 mutations

APOB – 1 mutation

PCSK9 – 1 mutation

Contact us

To find out more about the products that we offer, email us info@randoxbiosciences.com

 

 

 

 

 

 

 

 

 

 

 

 

 


We Are Randox | Randox Higher Level Apprentice Sarah Casey is awarded second place in NI WorldSkills Regional Final

A huge congratulations is in order for Science Higher Level Apprentice Sarah Casey who battled it out at the NI WorldSkills Regional Heat on 4th June to be awarded a well-deserved second place.

This was the first WorldSkills NI Regional Heat for Laboratory Technicians and was hosted at Southern Regional College, the Life Sciences Hub for Further Education in Northern Ireland.

The laboratory technician competition is based on real life scenarios in science that demonstrate technical competence in the use of complex instrumentation, laboratory equipment and skills. The competition is designed to reflect the work of a laboratory technician and tests their skills in techniques and procedures to solve practical problems through analysis, tests and measurements while ensuring safe and ethical working practices.

“This regional heat was a fantastic opportunity for higher education students across the sector to showcase their technical and analytical abilities.  The competitors have performed exceptionally well under such challenging conditions” said Dr. Asha Jamil, Life Sciences Hub Development Manager at Southern Regional College.

She continued; “Judges have come from a variety of specialist scientific backgrounds from both education and industry across the UK and I am delighted that competitors from NI had this opportunity to demonstrate their range of skills on such a prestigious platform.  Judges also commented that they were highly impressed by all the competitors’ technical and analytical skills and their professional approach to this challenging competition.” 

Judges were representatives from Middlesex University, Norbrook Laboratories, and also included the current Team UK Laboratory Technician winner, Tonicha Roberts, who is a Forensic Reporting Scientist with Eurofins Forensic Services, UK.

Competitors came from a range of higher education programmes from across the NI sector including Foundation Degrees and Higher Level Apprenticeship (HLA) programmes.  The HLA students study their underpinning Ulster University Foundation Degrees at Southern Regional College (Newry and Portadown campuses) and are employed with Norbrook Laboratories, Randox and Almac.

Sarah Casey, who was awarded second place, is currently a Southern Regional College student completing the Higher Level Apprenticeship in Applied Industrial Sciences (Life Sciences Pathway) in the Randox Science Park in Antrim. Sarah also won Southern Regional College’s Science Competition in January 2019.

The top performing competitors across the UK will now have a nail-biting wait to see if they have scored high enough to qualify for the WorldSkills UK Final at Birmingham’s NEC in November.   We wish Sarah the best of luck!

 

 

 

 

 

 

 

 

 

 

 

 


Q&A with Randox Testing Services: All Things Workplace Drug & Alcohol Testing

At Randox Testing Services, we are always trying to think of new ways to get the message across about the positive impact workplace drug & alcohol testing can have on an organisation. So, we decided to speak with one of our colleagues; Simon Tibbo, who is regularly engaging with companies about how to be proactive in minimising the risks of substance misuse.

Read below to find out what he had to say.

From your experience and knowledge, what industries are currently implementing testing programmes?

Apart from the finance industry, I’ve personally seen testing programmes within almost all business sectors, from the obvious, safety critical industries, Rail Track, Maritime, Construction, Logistics, all the way through to manufacturing firms, retail outlets, and even predominantly clerical companies. If a company has a workplace substance misuse policy and are looking to satisfactorily enforce the terms within, they will be engaged with a service provider, such as Randox, to properly support the policy.

 

What are, in your opinion, the barriers that companies face when trying to implement working drug & alcohol testing?

The introduction of a substance misuse policy to an already existing ‘company handbook’ can be a challenge, especially if the work-force has been established for some time. People don’t tend to like change, especially within the workplace. Unions can sometimes be unwelcoming to the idea of random testing and will often look to restrict the scope of testing or the policy itself. I’d say that each industry/company will likely meet its own barriers whilst developing and implementing a policy, and some may well be unique to the individual circumstances. Often, customers may implement an amnesty period prior to the commencement of a drug testing programme. This gives employees the opportunity to come forward and declare if they have a substance misuse issue which they can address together with their employer without sanctions.

 

Why has there been a delay in some companies developing workplace policies that directly relate to substance misuse?

There could be many reasons as to why a company hasn’t implemented a policy, but I’d expect somewhere near the top of that list would be either the assumption there isn’t a substance misuse issue within the business/industry, the worry that a substance misuse issue within the business/industry is highlighted by the introduction of a policy, and therefore creating more problems than its seen to be solving, or even that a company is simply unaware the solution is available and beneficial.

 

How important within a policy is it that a company clearly outlines what is expected of an employee, and the consequences of substance misuse?

Very! A policy needs to be clear and concise in its structure and procedures. If you aren’t explaining the terms or the consequences you could potentially end up with a problematic HR process and unresolvable tribunal cases. If an employee has sight of a straightforward policy they will know what to expect if the terms are breached, not to mention enforcing it should be equally as straightforward. It is also important to state why the policy is in place – i.e. to protect the workforce, the public and the company reputation.

 

Is it important to state cut-offs in substance misuse policies?

For alcohol, yes, most certainly. For drugs, not so much. An alcohol test with a home office approved breathalyser will provide an evidential result, which can be directly related to a ‘site cut-off’ (in the same manner as the existence of a road legal limit). Workplace drug testing should adhere to specific guidelines set-out by the EWDTS (European Workplace Drug Testing Society) in not just it’s procedures, but also its expected substance cut-offs. The cut-offs differ between substances so it’s not quite as straightforward. My suggestion would always be, if you feel it necessary to include drug cut-off information, refer to the EWDTS guidelines, they’re available to download on the EWDTS website if anyone needs sight, but ensure your provider is working to them and don’t go into full details, it’ll serve only to add unnecessary bulk to what should ideally be a streamlined policy.

 

How effective has workplace testing been in helping companies reduce the risk of drug & alcohol use?

From personal experience I can tell you, I’ve seen companies implement a policy/testing practice due to an awareness of substance misuse, only to reduce the volume of testing over time as the approach has proved successful in reducing or eradicating the specific problem. I’d say that’s a testament to implementing a random testing practice, it sends a sensible message in a fair and balanced manner, which ultimately gets results. If it’s done right, it’s going to be beneficial, even if it’s not particularly well received at its inception. Other examples where testing volume has been scaled back have led to an increase in the rates of positives demonstrating that an active testing programme is a deterrent to substance misuse.

 

Going forward, what industries do you see adopting a more proactive approach in use of substance misuse testing?

Likely most industries, every company has a duty of care to staff, contractors, visitors and/or the public. There will always be industries that don’t agree, don’t want to uncover issues or don’t believe they exist, but it’s the people that matter and the more that’s done to promote safety, welfare and overall good practice, the more industries will settle to the idea.

 

About Randox Testing Services

Randox Testing Services offer a wide range of products and services for the testing of illicit substances. We can craft customised packages to suit the needs of our customers, no matter what the industry.

Our expertise and experience working within this industry allow us to provide a range of testing solutions that will impact the risk of substance use in the workplace. With an extensive collection network and quality products, we can meet the needs of your business.

To find out more, contact us:

Email: testingservices@randox.com

Phone: +44 (0) 28 9442 2413

 

 

 

 

 

 

 

 

 

 

 

 


Syphilis and Confidante home STI test: screening for 10 infections

What is syphilis?

Syphilis is caused by the bacterium Treponema pallidum. Although spread through sexual contact, it is frequently passed to an unborn child by its infected mother, where it can cause congenital syphilis resulting in high rates of stillbirth and increased risk of infant mortality.

Primary syphilis is when sores appear at the point where the bacteria entered the body. These sores can appear anywhere such as: around the opening of the urethra, penis, foreskin and anus in men; the vulva, clitoris, cervix, urethra and anus in women.

Secondary syphilis occurs when untreated sores have appeared and healed. It is still infectious and maintains its ability to be passed on.Tertiary syphilis is a progression from untreated secondary forms of the infection. Left untreated, after many years, the infection can cause serious damage to the heart, brain, eyes, internal organs and nervous system, which can ultimately lead to death.

Important Statistics

Below are some statistics that have been published: about syphilis in recent years.

  • In 2017, there were approximately 422,000 diagnoses of sexually transmitted infections (STIs) made in England, around the same number that was reported in 2016.
  • There were 7,137 diagnoses of syphilis reported in 2017, a 20% increase (from 5,955) relative to the year prior and a 148% increase relative to 2008.
  • The impact of STIs remains greatest in young heterosexuals 15 to 24 years; black ethnic minorities; and gay, bisexual and other MSM
  • The increase in syphilis follows a 10-year trend, with 78% of diagnoses in gay, bisexual and other men who have sex with men (MSM).

How is the infection passed on?

Syphilis is passed on from one person to another through sex (vaginal, anal and oral) and also by direct skin contact with syphilis sores or rashes. Symptoms do not have to be visible for it to be passed on. It can still be transmitted before sores appear or after they have disappeared. Pregnant women can also pass syphilis onto their unborn baby.

What are the complications?

If syphilis is not treated effectively, it can spread to other parts of the body. This can result in long term complications, such as damage to the heart, brain, eyes and other organs. Ultimately, this damage can even lead to death.

Confidante Test

Confidante avoids any embarrassing examinations, allowing you to take a test in the privacy of your own home. The Confidante test is made to be quick and easy to use, with no technical jargon, making it extremely convenient.

Confidante is now only £40 with free postage and packaging (RRP £85). Your results will be delivered discreetly via post within 7 days and will not appear on your medical record.

If you want to read more about Confidante or buy a kit visit here, or contact a member of our team today.

 

 

 

 

 

 

 

 

 

 

 

 

 


Link between cocaine and disorder at football games

There has been an established link between disorder at football games and increasing cocaine use in society, according to Deputy Chief Constable Mark Roberts, the UK’s lead on football policing. Over the past two seasons, disorder at football matches has increased (45%), and has been linked to the increase prevalence of cocaine use inside stadiums.

According to the Home Office, 2.6% of 16 – 59 year olds took cocaine in 2017-18, up 2.4% in 2013-14. The drug in the UK is becoming cheaper, purer and more accessible than before. A senior football official said, when speaking with The Independent, that it is the “massive elephant in the room”, with police sources claiming that it is “rife” at football grounds across the country.

Football policing units carry out drug checks inside football stadiums with drug detection dogs and swabbing areas such as toilets. Arrests are made at the football grounds for drug possession. In 2017, cocaine related arrests at football grounds more than doubled from 32 to 68. These numbers may seem small, however DCC Mark Roberts says a reduction in match day policing, due to budget constraints, is the reason for these low numbers. 50% of games are either police-free (11.3%) or spotter only (39.3%).

Inspector Andy Bridgewater, the head of West Midlands’ Police football unit, believes there is a real cocaine problem stating that “there is a really strong correlation today between cocaine use and football-related violence.”

Overall disorder incidents at matches jumped 36% in 2016-17 and again last year, while cocaine-related deaths in England and Wales increased in 2017 for the sixth year in a row, from 112 in 2011 to 432 in 2017.

Using Randox Toxicology’s revolutionary Biochip Array Technology, the Evidence MultiSTAT is an automated analyser that enables detection of a wide variety of multiple drug groups and provides simultaneous on-site screening with our CE marked urine and blood panels. As minimal sample preparation is required, qualitative results can be provided in less than 20 minutes, offering an effective toxicology screen for cocaine and other drugs/drug metabolites.

To find out more about the Evidence MultiSTAT and our Biochip Array Technology visit www.randoxtoxicology.com or get in touch at info@randoxtoxicology.com.

 

 

 

 

 

 

 

 

 

 


Why is testing for Acetic Acid important in winemaking?

Acetic Acid in winemaking

When it comes to winemaking, the acidity in wine is an important component for the quality and taste. It adds a sharpness to the flavours and is detected most readily by a prickling sensation on the sides of the tongue and a mouth-watering aftertaste.

Acetic acid is a two-carbon organic acid produced in wine during or after the fermentation period. It is the most volatile of the primary acids associated with wine and is responsible for the sour taste of vinegar.

During fermentation, activity by yeast cells naturally produces a small amount of acetic acid. If the wine is exposed to oxygen, Acetobacter bacteria will convert the ethanol into acetic acid. This process is known as the “acetification” of wine and is the primary process behind wine degradation into vinegar.

Randox Food Diagnostics offer multiple tests for wine analysis including Acetic Acid on both the RX misano and the RX monaco.

Acetic Acid

Method Sensitivity Linearity
Manual N/A 0.3 g/l
RX misano 0.117 g/l Conc. Of standard
RX Monaco 0.03 g/l Conc. Of standard

For more information about our food testing for winemaking please contact us at: info@randoxfooddiagnostics.com

 

 

 

 

 

 

 

 

 


Testing for STIs with Confidante At Home Testing Kit

Sexually Transmitted Infections (STIs)

Sexually transmitted infections (STIs) are passed from one person to another typically through unprotected sex or genital contact.1 Some of the most common STIs are Chlamydia, Genital Warts, Herpes, Gonorrhoea, HIV and Viral Hepatitis. Over one million STIs are acquired every day worldwide.2

Not all STIs cause noticeable symptoms. You could have an STI and not know. Therefore it is essential to get regular health checks. Some STIs, like chlamydia, can be asymptomatic – i.e. they display no symptoms but can cause long-term complications like infertility.3

STI symptoms in women

  • yellow or green vaginal discharge
  • smelly discharge (often fish-like)
  • bleeding between periods
  • bleeding after sex
  • pain during sex

STI symptoms in men

  • discharge from penis tip
  • irritation of the urethra
  • swollen testicles

STI symptoms in both genders

  • pain when urinating
  • itching, burning or tingling around the genitals
  • blisters, sores, lumps or a rash around genitals or anus

Confidante At-Home STI Testing Kit

If you have recently entered a new relationship, experienced unprotected sex or are planning a family you should get tested for STIs, and may want to avail of our 10-plex STI test.

We offer a home testing sexually transmitted infection kit called ‘Confidante’ which enables you to be tested for 10 of the most common STIs. Confidante is designed to ensure a simple, hassle-free process where you will receive your results in 7 working days of posting your sample via email or telephone.

The process is straightforward and so simple: Buy Online / Register Kit Online / Collect Sample / Post / Receive Results.

For healthcare professionals, we also offer a Multiplex Sexually Transmitted Infection Array allowing you to outsource samples for STI testing. The CE-marked STI Array provides excellent precision, specificity, sensitivity and accuracy for STI diagnoses, which reduces the risk of false reporting and unnecessary confirmatory tests. Our simultaneous multiplex testing means smaller sample volumes are required, enabling faster throughput and rapid patient diagnosis saving you time and money.

STI Multiplex Array detects the following;

  • Chlamydia Trachomatis
  • Neisseria Gonorrhoea
  • Herpes Simplex 1
  • Herpes Simplex 2
  • Treponema Pallidum
  • Mycoplasma Hominis
  • Ureaplasma Urealticum
  • Mycoplasma Genitalium
  • Haemophilius Ducreyi
  • Trichomonas Vaginalis

Randox Clinical Laboratory Services

Tests for each of the STIs detailed above are run in Randox Clinical Laboratory Services (RCLS) in Antrim, Northern Ireland. RCLS is built upon Randox’s 35 years of experience and provides a clinical laboratory service designed to meet the time-sensitive, bespoke requirements of clinical and research projects globally.

RCLS have 4 UKAS ISO 17025 accredited testing laboratories No. 9329 – with unrivalled facilities across the UK. They are situated in Liverpool, London, Holywood and Randox Science Park Antrim. Within each of the locations there are a team of experienced scientists to support your project while you save money, time and labour.

There are a variety of analyser platforms available across the RCLS laboratories including the RX series of clinical chemistry analysers, along with our Evidence Series of multiplex immunoassay/molecular diagnostic systems, which utilise our intelligent Biochip Array Technology.  Each site also offers alternative third-party analysers.

To find out more information about Confidante sexual health testing, or RCLS, visit: https://www.confidantetest.com/ or email info@rcls.com. To find out more information about our STI Array visit: https://www.randox.com/sti-array/ or email info@rcls.com

  1. https://www.nhsinform.scot/illnesses-and-conditions/sexual-and-reproductive/sexually-transmitted-infections-stis
  2. https://www.who.int/news-room/fact-sheets/detail/sexually-transmitted-infections-(stis)
  3. https://onlinedoctor.lloydspharmacy.com/uk/info/sexual-health-information/what-is-a-sti

 

 

 

 

 

 

 

 

 


Alzheimer’s Disease testing on the Randox Evidence Series

What is Alzheimer’s Disease?

Alzheimer’s Disease is a progressive disease and is one of the most common kinds of dementia.

Our brains are made up of billions of tiny nerve cells which connect to each other. However, if you have Alzheimer’s Disease the connections between the cells are lost, which results in the loss of brain tissue and causes nerve cells to die1.

The brain is responsible for sending signals between cells. Those who suffer with Alzheimer’s have less ‘chemical messengers’ in their brain, so the signals are not passed on as well1.

The statistics of those who suffer with dementia is increasingly high and the figure is set to rise in the foreseeable future. Over 850,000 people are living with dementia in the UK. Studies states that one million people in the UK will have dementia in 2025 and this will increase to two million by 2050.2

Symptoms of Alzheimer’s Disease

The symptoms of Alzheimer’s disease are divided into 3 main stages; early symptoms, middle-stage symptoms and later symptoms.

In the early stages, the main symptom of Alzheimer’s disease is memory lapses which can increase anxiety or agitation. In the early stages, it is often mistaken that the person is forgetful and aren’t aware they are suffering with Alzheimer’s. The typical signs are listed below:3

  • forget about recent conversations or events
  • misplace items
  • forget the names of places and objects
  • have trouble thinking of the right word
  • ask questions repetitively
  • show poor judgement
  • become less flexible and more hesitant to try new things

As the disease progresses, the symptoms will gradually get worse. Memory problems will get worse which can make it difficult for the person who suffers with the disease to remember names of their loved ones, recent events and even remember birthdays and anniversaries. More symptoms such as the following will develop;3

  • increasing confusion and disorientation – for example, getting lost, or wandering and not knowing what time of day it is
  • obsessive, repetitive or impulsive behaviour
  • delusions or feeling paranoid and suspicious about carers or family members
  • problems with speech or language
  • disturbed sleep
  • changes in mood
  • difficulty performing simple tasks and may need additional support e.g. help with eating, getting dressed etc.

In the later stages of Alzheimer’s disease, the symptoms become increasingly severe and patients will need full-time care and assistance. It will be problematic for the individual to do basic everyday tasks such as getting changed, going to the toilet, getting washed and feeding themselves. They could lose their speech, and have difficulty eating and swallowing which can result in severe weight loss.

How Randox can help

Randox want to help. Our Evidence immunoanalyser has revolutionised laboratory screening worldwide with the capability to process 3,960 tests per hour and a sample capacity of 360. We offer the Apolipoprotein E4 (ApoE4) Array for Alzheimer’s genetic risk assessment, which is a research use-only product developed for the Evidence Investigator. The ApoE4 Array measures both total ApoE protein levels and ApoE4 protein levels directly from plasma samples and using a ratio can classify patients as negative or positive for ApoE4. In turn we can then assess their risk for the development of Alzheimer’s disease.

For further information about the Randox Alzheimer’s Array or our Evidence Investigator, please email info@randoxbiosciences.com       

 

  1. https://www.alzheimers.org.uk/about-dementia/types-dementia/alzheimers-disease
  2. https://www.dementiastatistics.org/statistics-about-dementia/prevalence/
  3. https://www.nhs.uk/conditions/alzheimers-disease/symptoms/

 

 

 

 

 

 

 

 

 


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