Heart attack test H-FABP 12 times faster than current methods

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Heart attack test H-FABP 12 times faster than current methods

As the supplier of a pioneering diagnostic able to assist with differentiating between coronary pain and non-cardiac chest pain, Randox Laboratories has this week welcomed news about the importance of introducing new innovations which can significantly improve patient outcomes.

Prioritising people presenting with a heart attack over those with non-cardiac chest pain is one of the biggest challenges A&E doctors face – there are around 200,000 heart attacks each year in the UK, but around 1 million people come to A&E with chest pains.  According to a team from King’s College London, as reported by the BBC, a faster, more accurate diagnosis of whether chest pain is caused by a heart attack would save the health service millions of pounds each year by sending well patients home and freeing up beds. Yet current testing methods do not efficiently differentiate between high-risk patients and the estimated 80% of patients who are not having a heart attack.

Randox’s revolutionary test for Heart-Type Fatty Acid-Binding Protein (H-FABP) however, when combined with current testing, is able to rule out a heart attack for patients who present at A&E with chest pain which is caused by other conditions such as respiratory issues, meaning they may not need emergency admission.

When measured at the time a patient presents to A&E with chest pain, H-FABP enables doctors to triage patients suffering with a heart attack more efficiently than before.

Dr. Gary Smyth, Medical Director at Randox Laboratories, hopes that more efficient testing will become widely available so that doctors can identify and prioritise patients at risk;

“Despite the best efforts of our NHS colleagues, EDs across the UK are under tremendous pressure.  In many cases people are presenting with chest pain but aren’t suffering from a heart attack, and given that current cardiac tests are not as sensitive as clinicians would like, these patients are being admitted unnecessarily, taking up beds and valuable resources.

 “It is imperative that newer, faster tests are adopted because fundamentally this means saving lives.”

H-FABP is released into the bloodstream within 30 minutes of a heart attack, whereas people who are currently admitted to hospital with chest pains may have to wait several hours for test results.  Even the latest heart attack test to be adopted by the NHS, troponin, can take up to six hours to provide confirmation.

H-FABP, conversely, is released from the heart during the early stages of a heart attack and because it is so small, it can be detected when the heart cells are being damaged, rather than at the stage when troponin would usually be detected – when cell death has already occurred.  The test can also be used to identify people who are at high risk of heart attack in the near future.

Dr. Peter FitzGerald, Founder and Managing Director of Randox Laboratories, commented;

“Research shows that patients who were troponin negative and therefore sent home from hospital, but who were positive for H-FABP, were at high risk of death – as high as a 20% chance of death that same year.

 “If the H-FABP test was added to existing tests upon arrival at hospital, doctors could quickly and accurately rule out the 80% of chest pain patients who are not having a heart attack, allowing resources to be focused on those who are actually at high risk.”

For further information on H-FABP, please visit http://www.randox.com/h-fabp/, or contact the Randox PR team by phoning (0) 28 9442 2413 or emailing randoxpr@randox.com


World Heart Day – 29th September 2017

World Heart Day – 29th September – Introduction

This year (29th September 2017) join us as we help to raise awareness for World Heart Day! The theme for this year’s World Heart Day is to share the power – and you know what they say… “Knowledge is Power” so throughout this blog we will be providing vital knowledge as well as tips to having a healthy heart!

The heart is a muscular organ that pumps blood around the body and is indeed central to your circulatory system. The system consists of a network of blood vessels, including, veins, arteries and capillaries. These vessels transport blood – as well as carrying oxygen and other important nutrients – to every part of the body. Ensuring a healthy heart is therefore vital.

What is CVD?

When too much pressure is put on our hearts we start to run into some issues – the general term for conditions affecting the heart is Cardiovascular Disease – better known as CVD. The exact cause of CVD is far from clear, with many factors increasing your chances of developing CVD. These risk factors can include, but are not limited to, high blood pressure, smoking, high cholesterol, being overweight or in many cases, can be hereditary.

It is important to note that Cardiovascular Disease is accountable for nearly half of all non-communicable disease (NCD) deaths, therefore making it the number one killer across the globe! Scary thought considering there are a whopping 17.3 million CVD related deaths per year – including stroke and heart disease. Understanding CVD in today’s society is more important than ever before, we need to know the truth about CVD and be able to decipher the facts from the fiction. Below you can see a few examples of common misconceptions regarding CVD and also some that are indeed true.

Only older men can get heart disease/CVD

False

Cardiovascular Disease can develop before birth

True

Exercising won’t help if you’re genetically predisposed to CVD

False

Low and middle-income countries are the most susceptible to CVD

True

It is estimated that by 2030 the number of deaths, due to CVD, will rise to an enormous 23 million globally! However, by raising awareness of the critical numbers and facts we can all help prevent CVD by making small, simple lifestyle changes.

Tips for a Healthy Heart

Using our “art into heart” graphic below, we decided to outline some of our Randox QC top tips for staying healthy! Why not try some of them and feel the effects of having a happy, healthy heart!

This World Heart Day, join us and many more around the world, to raise awareness for this great cause and unite together to “Share the Power”.


The RX series – Raising Awareness of Urology Week

This week marks Urology Week, an important week in the annual health calendar. Urology Week is an initiative of the European Association of Urology (EAU) that aims to raise awareness of urological conditions among the general public and provide knowledge into how vital urology is to your standard of life.

What is Urology?

Urology is a surgical speciality which involves the diagnosis and treatment of disorders of the kidneys, ureters, bladder, prostate and male reproductive organs. It is an extremely varied branch of medicine and caters for patients of both genders and all ages, from infants to elderly pensioners. (1)

Did you know?

There are 25 million or 16% of Europeans above 40 years of age who experience some symptoms of urinary incontinence, with costs of this condition totalling approximately €7 billion in just 6 countries? Currently, 10% of all medical care involves Urology which is a large proportion of the annual healthcare spend. (2)

The RX series Clinical Chemistry Analysers offer a comprehensive renal testing panel which allows for a quick and accurate diagnosis to combat urological diseases.

The RX series Renal Function Test Panel is aimed to help diagnose and manage conditions affecting kidney function; these tests may be used as part of general health screening or to screen someone who is at risk of developing kidney disease.

Why choose the RX series analysers to test Renal Function?

  • Extremely low patient sample volumes are required ensuring the upmost in patient comfort
  • Accurate testing ensures patients can receive correct treatment as early as possible
  • STAT functionality allows for the addition of emergency samples when required
  • Advanced QC capabilities insuring your results are both accurate and reliable.

View the Full RX series Test Menu Here

For more information please visit www.randox.com/clinical-chemistry-analysers or contact therxseries@randox.com to speak with your local Randox Representative.

 

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(1) The British Association of Urological Surgeons Limited. (2017). What Is Urology? Available: https://www.baus.org.uk/patients/information/default.aspx. Last accessed 26th Sept 2017.

(2) European Association of Urology. (2017). Urology Statistics.Available: http://www.urologyweek.org/what_is_urology/statistics/. Last accessed 26th Sept 2017.


Randox pledges support for PSNI in the fight against fentanyl

Global drug tests provider Randox Toxicology has today pledged its support for the PSNI in the fight against fentanyl, a strong painkiller which has been found for sale on the black market in Northern Ireland for the first time.

Fentanyl, which is an opioid pain medication currently classed as a controlled Class A drug under the Misuse of Drugs Act 1971, has been found in heroin which was seized by the PSNI, and has been linked to two deaths in Northern Ireland this year.

It is currently used to safely treat patients with severe pain, as it can be 50 to 100 times more potent than morphine. According to the National Crime Agency and Office for National Statistics however, 60 deaths in the UK in the past eight months have been attributed to misuse of fentanyl, which received international attention when the singer Prince was found to have died from a fentanyl overdose.

Dr. Peter FitzGerald, Founder and Managing Director of Randox Laboratories, commented;

“It is extremely worrying to hear that the PSNI have confirmed fentanyl has reached the black market in Northern Ireland.  The illegal sale of the painkiller has long been an issue in the USA, with the country having at least two million opioid addicts, but until now has not been used illegally in NI.

“Fentanyl’s status as a painkiller is potentially why it is so commonly abused, as those using prescription painkillers may turn to illicit substances, such as fentanyl, when their prescriptions run out.  With as little as 2mg able to cause an overdose, fentanyl is easily hidden and transported in small packages through the post, so poses a major danger to society.  The drug has high abuse potential and is being used more and more by drug dealers who can sell fentanyl at a cheaper price than heroin.”

Randox Toxicology, a specialist division of FitzGerald’s Antrim-headquartered Randox Laboratories, has today issued a statement to pledge its commitment to removing the danger of fentanyl from Northern Ireland.  The company’s significant investment in the research and development of new tests for drug detection has cemented its status at the forefront of the drugs screening industry.  Randox Toxicology, which developed its first fentanyl test in 2007, has the world’s only tests for the designer opiates U-47700, MT-45 and AH-7921.

Dr. Joanne Darragh, Head of Research and Development at Randox Toxicology, commented;

“In the endless pursuit of creating innovative tests for new drugs which emerge weekly on to the market, our expertise at Randox Toxicology sets us apart from the rest of the industry.  Not only have we been first to market with a number of opioid tests, but we have also developed our patented Biochip Array Technology, which enables us to simultaneously screen for both fentanyl and heroin, one of which may have been laced with the other.

“Today we pledge the support of our expertise, based on a decade’s worth of experience in developing fentanyl tests, to the PSNI in their efforts to remove the fentanyl threat from Northern Ireland. This is a problem that we must tackle together and we are confident that by highlighting this growing epidemic, we can educate communities on the devastating effects the misuse of fentanyl can have.”

For further information about Randox Toxicology’s fentanyl screrening please contact Randox PR on 028 9445 1016 or email RandoxPR@randox.com


Over 100 Dairy Cows put down following Ergotism Outbreak in New Zealand

This week over 100 cows on a farm in New Zealand had to be put down after digesting fungus from an infected feed supply. The herd in the Southland and Otago regions was suffering from ergot toxicity. Randox Food Diagnostics have developed the only test for this fungus on the market, which can protect your animals from injury or death.

Ergot Alkaloids are a naturally occurring fungus most commonly found in grains and grasses. Produced by a group of fungi called the Claviceps species, they infect seed heads of plants during the flowering period. The fungus replaces the developing grain with toxic ergot. The dry summer and wet autumn this year provided the optimum growing conditions for the fungus.

Typically, it causes lameness and swelling of the fetlocks and hock joints but in the most severe cases animals can lose tips of their tails, or ears or even their hooves. As in this case, it can result in animals being put down.

While all animals are at risk of contracting ergot, it is most commonly found in cattle.

According to the report, VetSouth Winton veterinarian Hayden Dore confirmed four cases have been reported in Southland and South Otago with a large number of infected cows.

“Over time it effectively causes one or more of the limbs to become gangrenous. Signs of ergot toxicity generally start with a disinterest in feed, before moving to lameness in the limbs, which presented similarly to foot rot, but without the separation of the toes. Once the limbs go cold from lack of blood supply, it would take about a week before the limbs began to fall off,” he said.

“One herd with 900 milking cows had around 130 cows infected by the poisonous fungus, with subsequently 61 of them being put down.”

Testing for Ergot Alkaloids

Randox Food Diagnostics offer the only array on the market to test for Ergot Alkaloids. Validated for flour and seed, the ELISA test offers excellent limits of detection for the toxin Ergotamine at 1ppb.

Click here for more information on the Ergot Alkaloid ELISA kit or email info@randoxfooddiagnostics.com and your area’s Business Development Executive will contact you.

Read the full story


Committed to meeting customers’ needs

At Randox Quality Control, we strive to meet and exceed customer expectations ensuring high quality products and superior customer service are at the top of our priority list.

How can Randox Quality Control help you?

High Quality QC

The Acusera range of true third party controls boasts an impressive range of benefits ultimately designed to help laboratories reduce costs and time while also ensuring an accurate and reliable test system.

The extended shelf life of our controls allows the same lot of control to be used for a period of up to 2 years keeping costly new lot validation studies to a minimum.  We may also be able to sequester lots on your behalf.

The availability of commutable controls designed to react to the test system in the same manner as a patient sample and controls targeted at clinical decision levels will not only help you to meet ISO 15189:2012 requirements but will effectively challenge instrument performance.

Click here to find out more about our QC range.

Customer support

The Randox global support network are on hand with expert advice to ensure timely, accurate and helpful resolution of any issues or queries you may have. The added benefit of quick delivery of product orders further highlights how we work with and for our customers to provide the best service available.

Customer Reviews

Don’t believe us? Read a few of the reviews we have received from laboratories around the world;

“I would like to thank the Randox team for the excellent service when helping to reserve and manage our IQC orders, lot numbers and stock.” – Chief Biomedical Scientist, London, 2017.

Request your free QC consultation by contacting us today! Get in touch and we can arrange for your laboratory to have a consultation with one of our Randox QC specialists. Alternatively, if you would like to leave us a review you can do so by emailing acusera@randox.com.


The RX series celebrate Diabetes Awareness Week

This week the RX series team celebrate Diabetes Awareness Week. This is an annual event in the UK calendar, giving public the chance to raise as much awareness as possible for the condition and get involved with taking preventative action.

Diabetes is a chronic disease which causes a person’s blood sugar level to become too high. Since 1996, the number of people diagnosed with diabetes in the UK has risen from 1.4 million to 3.5 million. Of these, about 270,000 have type 2 diabetes and around 300,000 have type 1 diabetes. ₁

Diabetes prevalence in the UK is likely to rise to 5 million by 2025, therefore if we know our risks and are aware of symptoms, we can do something about this staggering figure. Certain risks associated with diabetes include age, family history, high blood pressure and being overweight. As this disease continues to challenge healthcare today it is important we take action on Diabetes Awareness Week.

Signs and symptoms of diabetes include unexplained weight loss, frequent urination, tiredness and lack of energy, excessive thirst, blurred vision, tingling sensation/numbness in the hands or feet and slow-healing wounds.

Whilst the condition cannot be cured, it is treatable and can be managed and controlled with different treatments to suit different people. There are several assays that Randox have developed to monitor and diagnose diabetes. These include; Fructosamine, Glucose and HbA1c. Monitoring diabetes is hugely important to ensure that you are safe from complications.

The RX series includes a vast Diabetes test Panel.

#DiabetesAwarenessWeek has allowed us to focus on how we can take action by diagnosing and monitoring diabetes effectively.  See below three tests run on the RX series for monitoring and diagnosing diabetes.

Glucose

High levels of glucose present in the blood over a sustained period of time can end up damaging the blood vessels. Glucose comes from carbohydrate foods and it is the main source of energy used by the body. Insulin is a hormone that helps your body’s cells use the glucose and helps ensure levels don’t rise too high.

HbA1c

HbA1c is a very common test used indicating the blood glucose levels for the previous two to three months. HbA1c levels are directly correlated with increased risk of diabetes related deaths, making HbA1c tests vital.

Fructosamine

Fructosamine testing enables an accurate review of a person’s average blood glucose level, and therefore diabetic status over a period of 2-3 weeks. Fructosamine testing is required for medication changes, gestational diabetes, red blood cell concerns and comorbidities.

 

If you would like to educate yourself more on Diabetes, including the diagnosis and monitoring, complications monitoring and associated biomarkers visit our website. We also have a full test menu available here.

Check out www.diabetes.org.uk for ways in which you can be a part of Diabetes Awareness Week this 2017!

Don’t forget to keep posted on our social media accounts for more educational information all week, remember use the hashtags to join in! #KnowDiabetes #DiabetesWeek #FightDiabetes

  1. Diabetes UK. (2017). Facts and Figures . Available: https://www.diabetes.org.uk/Professionals/Position-statements-reports/Statistics/. Last accessed 14th June 2017

Lipoprotein(a) Foundation commend celebrity personal trainer, Bob Harper, as he speaks out about the risk of Lp(a)

The Lipoprotein(a) Foundation have commended health and fitness expert Bob Harper for speaking out after recently suffering a heart attack. The celebrity personal trainer and host of the US television series ‘The Biggest Loser’, has revealed that high levels of Lp(a) were responsible for the heart attack he suffered at the age of 51 at the beginning of this year.1

Harper had been completing a normal workout at his gym when he suffered full cardiac arrest. Luckily, two doctors were in the vicinity who saved his life by performing CPR and using an Automated External Defibrillator (AED). In an interview following his heart attack, Harper has said,

“I’ve learned a lot about the fact genetics does play a part in this, it is so important to know your health… I’m a guy that lives a very healthy lifestyle, very regimented, I work out all the time, but there were things going on inside of my body that I needed to be more aware of and I strongly encourage anyone that’s listening right now to go to their doctor, get their cholesterol checked, see what’s going on on the inside”.

Scroll down to watch the interview in full.

What is Lp(a)?

Lp(a) is a particle which is produced in the liver and found in the blood which carries cholesterol, fats and proteins. Levels of Lp(a) in individuals are genetically determined, and are not affected by diet, exercise or lifestyle changes.2

So how does a seemingly fit and healthy person have a heart attack at the age of 51?

Lp(a) is currently the strongest inherited risk factor for heart attack and stroke, with one in five people globally inheriting high Lp(a).1 Levels of Lp(a) are not routinely tested in standard cardiovascular assessments, and despite the particle itself being an altered form of LDL cholesterol, standard cholesterol tests do not reveal inherited Lp(a) levels as it is independent from total cholesterol and LDL levels.3

High Lp(a) can also be unrelated to other common risks factors of cardiovascular diseases for example, smoking, diet, diabetes, high blood pressure and lack of exercise. This is why seemingly healthy individuals can have high Lp(a) in their genes and still be at high risk of cardiovascular diseases.

Why is Lp(a) not routinely measured if high levels pose such a risk?

The widespread use of Lp(a) as an independent risk factor for cardiovascular disease risk has, until recently, been hindered by the lack of internationally accepted standardisation and the fact that many commercial Lp(a) methods suffer from apo(a) size related bias, potentially leading to patient misclassification.

The size of the apo(a) protein is genetically determined and varies widely hence, levels of Lp(a) can vary up to 1000-fold between individuals.4 To find out more about the clinical significance of Lp(a), please refer to the section below entitled ‘For Health Professionals’.

What can you do if you have high Lp(a)?

Research has shown that lowering Lp(a) could significantly reduce the impact of cardiovascular diseases. A recent study published in the American Heart Association journal, Arteriosclerosis, Thrombosis and Vascular Biology, found that reducing high Lp(a) could potentially prevent up to 1 in 14 cases of myocardial infarction (heart attack) and 1 in 7 cases of aortic valve stenosis.5 Of those studied, nearly one third of heart attacks and half of all cases of aortic stenosis were attributed to high Lp(a).6 This study demonstrates the clinical significance of measuring Lp(a), making it a major independent genetic risk factor for cardiovascular diseases.

Why test Lp(a)?

Lp(a) will be tested as part of a lipid profile if: there is a strong family history of CVD, a patient has existing heart or vascular diseases, a patient has an inherited predisposition for high cholesterol or if a person has had a stroke or heart attack but has normal lipid levels.7

Dr Christie Ballantyne, Chief of Cardiology at Baylor College of Medicine, has said “the most important part of knowing your Lp(a) level is understanding your overall risk and finding the right lifestyle modifications or medications to target all the other traditional risk factors. Those risk factors become even more important to monitor when your Lp(a) levels are high”.8

For patients

If you are concerned that you may be at risk of having elevated levels of Lp(a) due to your family history, ask your doctor or medical provider to test lipoprotein (a), along with other lipid tests, to clinically evaluate your risk of developing cardiovascular diseases.

For health professionals

Click below for information regarding the challenges associated with the measurement of Lp(a) and the clinical significance it holds.

The widespread use of Lp(a) as an independent risk factor for cardiovascular disease risk has, until recently, been impeded by the lack of internationally accepted standardisation and the fact that many commercial Lp(a) methods suffer from apo(a) size related bias, potentially leading to patient misclassification. The size of the apo(a) protein is genetically determined and varies widely hence, levels of Lp(a) can vary up to 1000-fold between individuals.4 

As a result, international criteria has been set to overcome these challenges. The International Federation of Clinical Chemistry (IFCC) Working Group on Lp(a) recommends that laboratories use assays which do not suffer from apo(a) size-related bias, in order to minimise the potential risk of misclassification of patients for coronary heart disease. The Lipoprotein(a) Foundation has referenced Marcovina and Albers (2016) as their recommendation for the best Lp(a) test.9 This recommendation is a result of the following conclusions:

  • Robust assays based on the Denka method are available, which are reported in nanomoles per litre (nmol/L) and are traceable to WHO/IFCC reference material
  • Five point calibrators with accuracy assigned target values will minimise the sensitivity to apo(a) size

A number of guidelines are in place for the testing of Lp(a) in patients.

-The European Guidelines for Management of Dyslipidaemia state that Lp(a) should be measured in individuals considered at high risk of CVD or with a strong family history of premature CVD.

-The European Atherosclerotic Society suggest that Lp(a) should be measured once in all subjects at intermediate or high risk of CVD/CHD who present with10 :

1. Premature CVD
2. Family hypercholesterolaemia
3. A family history of premature CVD and/or elevated Lp(a)
4. Recurrent CVD despite statin treatment
5.
≥3% 10-year risk of fatal CVD according to the European guidelines
6.  ≥10% 10-year risk of fatal and/or non-fatal CHD according to the US guidelines

-EAS Consensus Panel states the evidence clearly supports Lp(a) as a priority for reducing cardiovascular risk, beyond that associated with LDL cholesterol.  Clinicians should consider screening statin-treated patients with recurrent heart disease, in addition to those considered at moderate to high risk of heart disease.

  • The Randox Lp(a) assay is one of the only methodologies on the market that detects the non-variable part of the Lp(a) molecule and therefore suffers minimal size related bias – providing more accurate and consistent results. The Randox Lp(a) kit is standardised to the WHO/ IFCC reference material SRM 2B and is closest in terms of agreement to the ELISA reference method.
  • Five calibrators with accuracy-based assigned target values are provided – which accurately reflect the heterogeneity of isoforms present in the general population
  • Measuring units available in nmol/L upon request
  • Highly sensitive and specific – method for Lp(a) detection in serum and plasma
  • Applications are available for a wide range of biochemistry analysers – which detail instrument-specific settings for the convenient use of Randox Lp(a) on a variety of systems
  • Liquid ready-to-use reagents – for convenience and ease-of-use

For further information on Lp(a), click here or email: reagents@randox.com

Watch the interview with Bob Harper here:

1. Lipoprotein(a) Foundation, Lipoprotein(a) Foundation Thanks Bob Harper for Revealing High Lp(a) Levels Led to His Recent Heart Attack on The Dr Oz Show, 2017 Available from: http://www.businesswire.com/news/home/20170425006724/en/ [Accessed: 16 March 2017]

2. Lipoprotein Foundation, Understand Inherited Lipoprotein (a), Available from: https://goo.gl/bH5A8R [Accessed: 16 March 2017]

3. Kumar, V., Abbas, A. K. and Aster, J. C., Robbins and Cotran Pathologic Basic of Disease, (Philadelphia: Elsevier Saunders, 2015), p. 494 in Google books, https://goo.gl/VEnVX9 [Accessed 27th April 2017]

4. Kamstrup P.R., Tybjaerg-Hansen A., Steffensen R., Nordestgaard B.G. Genetically elevated lipoprotein (a) and increased risk of myocardial infarction. JAMA. Vol. 301, p. 2331-2339 (2009).

5. Afshar, M. Kamstrup, P.R., Williams, K., Snidermann, A. D., Nordestgaard, B.G., Thanassoulis, G., Estimating the Population Impact of Lp(a) Lowering on the Incidence of Myocardial Infarction and Aortic Stenosis – Brief Report., Ateriosclerosis, Thrombosis, and Vascular Biology, 2016;36:2421-2423, Available from: http://doi.org/10.1161/ATVBAHA.116.308271

6. The Lipoprotein(a) Foundation, Lipoprotein(a) Foundation Supports National Heart Valve Disease Month, Highlights Genetic Link between Lp(a) and Aortic Valve Disease, Business Wire. (2017), Available from: https://goo.gl/LhQFGj [Accessed: 16 March 2017]

7. Lab Tests Online, Lp(a), 2014, Available from: https://goo.gl/W2PWSN [Accessed: 16 March 2017]

8.Gutierrez, G., The heart attack risk factor you haven’t heard of, Baylor College of Medicine, 2017, Available from: https://goo.gl/9X4Xko [Accessed: 16 March 2017]

9. Marcovina, S.M. and Albers, J.J. Lipoprotein (a) measurements for clinical application. Lipid Res. Vol. 57, p. 526-37 (2016).

10. Nordestgaard, B. G., Chapman, M. J., Ray, K., Bore´n, J., Andreotti, F., Watts, G. F., Ginsberg, H., Amarenco, P., Catapano, A., Descamps, O. S., Fisher, E., Kovanen, P. T., Kuivenhoven, J. A., Lesnik, P., Masana, L., Reiner, Z., Taskinen, M. R., Tokgozoglu, L., and Tybjærg-Hansen, A., for the European Atherosclerosis Society Consensus Panel. Lipoprotein(a) as a cardiovascular risk factor: current status. European Heart Journal. Vol. 23, p. 2844-2853 (2010).

lipoprotein(a)


A week dedicated to unsung heroes! – Medical Laboratory Professionals Week 2017

From April 23rd to April 29th we are celebrating Medical Laboratory Professionals Week! This is a week dedicated to raising awareness for those who work in a laboratory & the hard work that goes unnoticed every day in laboratories around the world.

Have you ever wondered what happens between submitting your patient sample and receiving your results? Have you ever wondered who conducts the detailed laboratory testing for your annual check-up such as cholesterol and glucose levels? Or who analyses these results? The answer, a Medical Laboratory Professional (MLP). MLP’s provide up to 70% of the medical laboratory results for physicians and others to make informed decisions about a patient’s diagnosis and aftercare treatment plan. The work that laboratory professionals do each and every day is integral to providing excellent patient care.  They perform and interpret billions of laboratory tests every year.

Providing accurate and reliable test results is of the utmost importance for laboratory professionals and also for us at Randox. With a passion for Quality Control, and with more than 30 years’ experience developing Laboratory QC for the in vitro diagnostics market, we believe in producing high quality material designed to streamline procedures, whilst reducing costs in laboratories of all sizes and budgets. These qualities have been reflected in our Acusera true third party quality controls, Acusera 24.7 interlaboratory data management software, Acusera Verify Calibration Verification material and RIQAS, the largest international EQA scheme.

Randox Quality Control would like to take this opportunity to thank all the laboratory professionals around the world and especially our own laboratory staff – you truly are the “Unsung Heroes of Healthcare”.


Celebrating the Randox Reagents R&D Team this Medical Laboratory Professionals Week!

Medical Laboratory Professionals Week (MLPW) is a week dedicated to increasing public understanding and appreciation for the clinical laboratory profession. During this week, we are taking the opportunity to celebrate the hard work of our Research and Development team. Allow us to provide you an insight into the life changing work of our scientists in the laboratories.

At Randox, our scientists work tirelessly to develop revolutionary diagnostic tests that are used in hospital and research laboratories across the globe.

We spoke to one of our biochemistry R&D Scientists to gain an insight into what working in a clinical chemistry laboratory entails. Emmett Donnelly, Clinical Chemistry R&D Scientist, is involved in the development of new reagents and the improvement of existing reagents. Emmett commented, “[My] role also involves the transfer and testing of existing chemistries onto new analyser platforms. Troubleshooting and resolving customer queries also forms part of a clinical analyst’s role”.  Emmett’s work is vital to ensure that patient tests are performing correctly, and to develop ground-breaking new technologies leading to better patient outcomes. To find out more about the work Emmett does, watch this video below.

Our scientists are committed to research and development and thrive knowing that their novel research is putting them at the forefront of clinical diagnostics.

In fact, prior to beginning work at Randox, Scott Paulin, Clinical Chemistry R&D team, took part in a three month expedition to Antarctica to intensely study human response-based research in athletes. A number of papers have been published in peer reviewed journals as a result of Scott’s research, as the findings have provided a useful insight into the physiological stress and responses associated with an Antarctic ultra-endurance race and nutritional counterstrategies to help maintain immune responses, function body weight and reduce stress markers. Read the full article here.

At Randox, our scientists are of the highest calibre, with vast experience and expertise which ensures we are producing the highest quality range of clinical diagnostic tests.

Excitingly as a result, American astronauts have enlisted our help to test their antioxidant levels before they go to space! This is essential as it ensures astronauts can survive long periods of time away from earth. To find out more about how important our Total Antioxidant Status (TAS) test is for astronauts, read our blog post here.

The invaluable work our scientists undertake in the laboratory is vital to ensure healthcare is advanced globally. Thanks to those in our Research and Development team, we are proud to be able to offer the widest range of clinical chemistry reagents and unique tests for medical diagnosis. Due to our scientist’s dedication to research, a continual focus is placed on developing tests that assess the risk of diseases, rather than diagnosing the illness after it has occurred. As a result, Randox are helping to change healthcare, as patients are provided the ability to take preventative action early. In the words of our R&D scientist Emmett Donnelly, “for me, my work supports the old saying prevention is better than cure”.

We hope you have enjoyed reading about our fantastic team of R&D Scientists! If you would like to find out more about the work of Randox Reagents, please get in contact by emailing: reagents@randox.com or click here to view our homepage.

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