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Veterinary Diagnostic Reagents
High Quality Open Channel Tests, Validated For Veterinary Use
Benefits of Randox Diagnostic Veterinary Reagents
Comprehensive Test Menu
A comprehensive test menu encompassing 48 diagnostic veterinary assays, including a variety of assays unique to Randox
Superior Methodology
Superior methodologies ensuring accurate & reliable results compared to traditional methods
Reduce Costs
Versatile test menu enabling laboratories to reduce costs with in-house testing
Excellent Correlations
Excellent correlations to gold standard & commercial methods, providing confidence in patient results
Validated For Use
The Randox diagnostic veterinary reagents are scientifically proven and validated for use with a diverse range of animal species
Applications Available
Applications available detailing instrument-specific settings for the convenient use of Randox Veterinary Reagents on a variety of clinical chemistry analysers
Open Channel Diagnostic Veterinary Reagents
| Alanine Aminotransferase (ALT) | Cholesterol (LDL) | Glucose | Sodium |
| Albumin | Cholesterol (Total) | Glutathione Peroxidase (Ransel) | Superoxide Dismutase (Ransod) |
| Aldolase | Cholinesterase (Butyryl) | Glutathione Reductase | Total Antioxidant Status (TAS) |
| Alkaline Phosphatase | CK-NAC | Iron | Total Iron Binding Capacity (TIBC) |
| Ammonia | CO2 Total | Lactate | Total Protein |
| Amylase | Copper | Lactate Dehydrogenase (L-P) | Triglycerides |
| Aspartate Aminotransferase (AST) | Creatinine | Lactate Dehydrogenase (P-L) | Urea |
| Bile Acids (4th Gen) | CRP (Canine) | Lipase | Uric Acid |
| Bile Acids (5th Gen) | D-3 Hydroxybutyrate (Ranbut) | Magnesium | Urinary Protein |
| Bilirubin (Direct) | Fructosamine | NEFA | Zinc |
| Bilirubin (Total) | Gamma GT | Phosphorus (Inorganic) | |
| Cholesterol (HDL) | GLDH | Potassium |
| Aldolase | CRP (Canine) | Glutathione Peroxidase (Ransel) | Superoxide Dismutase (Ransod) |
| Bile Acids (5th Gen) | Creatinine (Enzymatic) | Glutathione Reductase | Total Antioxidant Status (TAS) |
| Copper | D-3-Hydroxybutyrate (Ranbut) | Non-Esterified Fatty Acids (NEFA) | Zinc |
Product availability may vary from country to country. Some product may be for Research use Only. For more information on product application and availability, please contact your local Randox Representative.
Superior Performance & Unique Diagnostic Veterinary Reagents
Copper is one of the several essential trace elements in animal life required for red and white blood cell formation, healthy nerve fibres, pigmentation, wool growth and bone growth 1. In animals, whilst copper deficiency is one of the most commonly diagnosed trace element deficiencies, over-supplement of copper can lead to copper toxicity 2.
Copper deficiency is common in bovines, mainly cattle and sheep, caused by two factors: low copper levels in plants in copper-deficient soils, and an induced deficiency due to ingesting excessive levels of other elements, including: sulphur, iron and molybdenum in feed supplements or pastures 1.
On the other hand, bovines such as sheep and calves prior to weaning are the most susceptible to copper toxicity. This can occur as a result over excessive ‘therapeutic’ amounts of copper are added to the feed to avoid copper deficiency, however, it’s more commonly the result of long-term ingestion of copper in quantities which exceed the nutritional requirements 3.
Diabetes mellitus (DM), is commonly observed in middle aged and older canines and felines. Certain conditions predispose canines and felines to DM, including being overweight, inflammation of the pancreas, and certain medications which interfere with insulin, such as glucocorticoids. DM can also occur in the young which is attributed to a genetic factor. DM is more commonly observed in female canines and male felines 4.
Fructosamine testing is utilised to evaluate a canine or feline’s response to treatment which provides the canine or feline’s average glucose concentrations for the previous 7 to 14 days 5.
The NBT method is commonly utilised in fructosamine testing, however Randox offer the enzymatic method which improves specificity and reliability. The Randox enzymatic fructosamine assay displayed a correlation coefficient of r=0.9192 when compared to the NBT method.
Non-esterified fatty acids (NEFA) reflects the energy status of animals, with high NEFA concentrations indicating a negative energy balance. A negative energy balance occurs when caloric intake is lower than energy expenditure. High serum NEFA concentrations and a negative energy balance are risk factors for metabolic disease 6.
Energy balance is one of the most critical nutritional factors affecting animal health, reproductive performance and lactation 7. A negative energy balance has been observed in several animal species and should be observed especially in bovine (cattle, goats, sheep), feline and equines.
Superoxide dismutase (SOD) is an enzyme responsible for catalysing the dismutation of superoxide radicals (O2-), a primary reactive oxygen species (ROS) produced by the body, to hydrogen peroxidase (H2O2) and molecular oxygen (O2), the inadvertent by-products of aerobic metabolism. Consequently, SOD plays an integral role in protecting the body from oxidative stress 8, 9, 10.
SOD measurement is particularly useful in endurance horses as oxidative stress increases with prolonged endurance training. Decrease levels of SOD can cause fatigue, muscle damage, stiffness, and decreased performance 11.
SOD measurement is also useful in dairy cows who experience oxidative stress and a reduce antioxidant defence capacity during postpartum period and lactation 12.
Zinc is an essential trace mineral in animals and is required for the normal functioning of organisms. Involved in several biochemical processes, including: RNA and DNA expression and cellular use of oxygen and respiration, sequestration of free radicals, protection against lipid peroxidation and maintenance of cell membrane integrity 13.
In canines, zinc is not easily or readily absorbed in the intestines. The absence of zinc in canines causes various abnormalities affecting the immune system, metabolic function and the skin. Moreover, zinc deficiency can cause zinc responsive dermatosis, a keratinisation disorder (abnormal skin production) 14.
Zinc toxicity has been observed in exotic, large and wild animals due to dietary indiscretions. Zinc toxicity causes decreased weight and milk production in large animals and lameness and epiphyseal in foals 15.
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References
[2] Van Saun RJ. Food Animal Practice. : Saunders WB; 2009. http://www.sciencedirect.com/science/article/pii/B9781416035916100405 (accessed 11 November 2019).
[3] Erickson E. Copper deficiency in sheep and cattle. https://www.agric.wa.gov.au/feeding-nutrition/copper-deficiency-sheep-and-cattle (accessed 11 November 2019).
[4] Washington State University. Diabetes Mellitus. https://www.vetmed.wsu.edu/outreach/Pet-Health-Topics/categories/diseases/diabetes-mellitus (accessed 14 November 2019).
[5] NADIS Animal Health Skills. Chronic Copper Toxicity. https://www.nadis.org.uk/disease-a-z/cattle/chronic-copper-toxicity/ (accessed 11 November 2019).
[6] Bidewell C, Livesey C. Copper poisoning: an emerging disease in dairy cattle. Veterinary Laboratories Agency ; (): 16-19. https://pdfs.semanticscholar.org/6282/64c8b58d44018a5527d5a58162e0bdf82e95.pdf (accessed 11 November 2019).
[7] Williams K, Ruotsalo K, Tant MS, Downing R. Diabetes in Cats – Testing and Monitoring. https://vcahospitals.com/know-your-pet/diabetes-in-cats-testing-and-monitoring (accessed 14 November 2019).
[14] Primovic D. Overview of Zinc Deficiency in Dogs. https://www.petplace.com/article/dogs/pet-health/dog-health/zinc-deficiency-zinc-responsive-dermatosis-in-dogs/ (accessed 21 November 2019).
[15] Cahill-Morasco R. Overview of Zinc Toxicosis. https://www.msdvetmanual.com/toxicology/zinc-toxicosis/overview-of-zinc-toxicosis (accessed 21 November 2019).
