Next-generation āanti-cancer weaponsā to be developed in innovative partnership between Randox and Transgene
Next-generation āanti-cancer weaponsā to be developed in innovative partnership between Randox and Transgene
Randox Laboratories has today announced an innovative European partnership with French biotech company Transgene, which aims to develop a game-changing therapy for cancer treatments.
It involves cutting-edge technology and ‘anti-cancer weapons’ in the form of oncolytic viruses which directly target and destroy the cancer cells, and also deliver antibodies in the tumour microenvironment to further attack the rest of the tumour. This has clear advantages over traditional treatments such as radiotherapy and chemotherapy which as well as targeting cancer cells, can affect healthy cells.
In addition, if successful, this therapy will address the efficacy challenges faced by either Oncolytic viruses or Check-point inhibitors’ neutralization used independently, as their combination is expected to trigger a sustained anti-tumoural immune response from the patient.
The partnership will bring together Randox’s unique collection of therapeutic single domain antibodies (sdABs), which are on the front line in the fight against cancer, and Transgene’s next-generation viral platform Invir.IO™.
Commenting on the agreement, Dr. Peter FitzGerald, Managing Director and Founder of Randox Laboratories, said:
“This collaboration will enable ground-breaking innovation and research to be carried out in a critical area of human health. The work we will be doing in the field of cancer treatment has an enormous potential benefit for patients through the delivery of more effective treatments. We are looking forward to working with Transgene to generate oncolytic viruses that will be able to deliver single and multiple payloads directly into the tumour, enhancing their efficacy. This partnership will allow us to better leverage our SdAb capabilities and immuno-oncology expertise, and add to our strategic collaborations across the world.”
Eric Quéméneur, PhD, Executive VP and VP Research & Development of Transgene, said:
“We are delighted to collaborate with Randox. Its library of SdAbs against major targets in immuno-oncology provides an excellent opportunity to demonstrate the high potential of our Invir.IO™ platform. We look forward to working with Randox and to generating novel product candidates which combine the merits of oncolytic virotherapy and local delivery of therapeutic payloads. We believe such targeted expression of therapeutic agents including immune checkpoint inhibitors will better potentiate the tumour microenvironment and paves the way for the development of a broad range of innovative cancer treatments.”
For further information about Randox’s collaboration with Transgene, please visit our Randox Biosciences website. Click here.
If you have any additional questions please contact Randox PR by phoning 028 9442 2413 or emailing RandoxPR@randox.com
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At Randox Quality Control, we strive to meet and exceed customer expectations ensuring high quality products and superior customer service are at the top of our priority list.
How can Randox Quality Control help you?
High Quality QC
The Acusera range of true third party controls boasts an impressive range of benefits ultimately designed to help laboratories reduce costs and time while also ensuring an accurate and reliable test system.
The extended shelf life of our controls allows the same lot of control to be used for a period of up to 2 years keeping costly new lot validation studies to a minimum. We may also be able to sequester lots on your behalf.
The availability of commutable controls designed to react to the test system in the same manner as a patient sample and controls targeted at clinical decision levels will not only help you to meet ISO 15189:2012 requirements but will effectively challenge instrument performance.
Click here to find out more about our QC range.
Customer support
The Randox global support network are on hand with expert advice to ensure timely, accurate and helpful resolution of any issues or queries you may have. The added benefit of quick delivery of product orders further highlights how we work with and for our customers to provide the best service available.
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Request your free QC consultation by contacting us today! Get in touch and we can arrange for your laboratory to have a consultation with one of our Randox QC specialists. Alternatively, if you would like to leave us a review you can do so by emailing acusera@randox.com.
Liquid CSF Quality Control
Providing a true third party solution for the measurement of Cerebrospinal Fluid (CSF), the Acusera Liquid CSF Control is designed to deliver an unbiased, independent assessment of analytical performance for 14 analytes, helping to ensure the results clinical laboratories release are accurate and reliable.
With an extended open vial stability of 30 days at 2oC – 8oC, the Acusera Liquid CSF Control will reduce waste, while remaining easy and convenient to use.
Features & Benefits
- Liquid ready-to-use samples requiring no preparation
- Human based material
- True third party control providing unbiased performance assessment
- Assayed target values available
- Shelf life of 2 years from the date of manufacture
- Open vial stability of 30 days for all analytes when stored at 2oC to 8oC
| Description | Size | Analytes | Cat No | |
|---|---|---|---|---|
| Liquid CSF Control Level 1 | 10 x 3ml | 14 | CF10138 | |
| Liquid CSF Control Level 2 | 10 x 3ml | 14 | CF10139 | |
Analytes
- Albumin
- Albumin (electrophoresis)*
- Alpha – 1- globulin (electrophoresis)*
- Alpha – 2- globulin (electrophoresis)*
- Beta- globulin (electrophoresis)*
- Chloride
- Gamma – globulin (electrophoresis)*
- Glucose
- hsIgA*
- hsIgG
- hsIgM*
- Lactate
- Protein (Total)
- Sodium
*No claims are made regarding values and stability.
Canine CRP Quality Control
A dedicated control designed for the use in the quality control of the Randox Canine CRP assay.
Features & Benefits
- Liquid ready-to-use
- Human CRP in a stabilised protein matrix
- Stable to expiry date at 2oC – 8oC
- Once open stable to expiry date at 2oC – 8oC
| Description | Size | Analytes | Cat No | |
|---|---|---|---|---|
| Canine CRP Control Level 2 | 3 x 1ml | 1 | CP2803 | |
| Canine CRP Control Level 3 | 3 x 1ml | 1 | CP2804 | |
Analytes
- Canine CRP
Cystatin C Quality Control
Dedicated Cystatin C control designed for use in the routine monitoring of both accuracy and precision. Supplied in a convenient, liquid ready-to-use format, no preparation is required. Assayed target values and ranges are provided for this true third party control.
Features & Benefits
- Liquid ready-to-use
- 100% human serum
- Assayed target values provided
- Stable to expiry date at 2°C – 8°C
- Open vial stability of 30 days at 2°C – 8°C
- Multi-point calibrator available
| Description | Size | Analytes | Cat No | |
|---|---|---|---|---|
| Cystatin C Control Level 2 | 3 x 2ml | 1 | CYS10446 | |
| Cystatin C Control Level 3 | 3 x 2ml | 1 | CYS10447 | |
Analytes
- Cystatin C
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High Sensitivity CRP Quality Control
The Randox Acusera High Sensitivity CRP quality control is designed to monitor the performance of high sensitivity CRP assays. The liquid ready-to-use format makes it convenient and easy to use. Once opened the control is stable to expiry at +2-8°C significantly minimising waste and helping to reduce costs.
Powered by BiozFeatures & Benefits
- Liquid ready-to-use
- 100% human serum
- Assayed target values provided
- Stable to expiry date at 2°C – 8°C
- Once opened stable to expiry date at 2°C – 8°C
| Description | Size | Analytes | Cat No | |
|---|---|---|---|---|
| High Sensitivity CRP Control Level 1 | 10 x 1ml | 1 | CP2476 | |
| High Sensitivity CRP Control Level 2 | 10 x 1ml | 1 | CP2477 | |
Analytes
- CRP
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CRP Quality Control
The Randox Acusera CRP quality control is designed to monitor the performance of traditional CRP assays. The liquid ready-to-use format makes it convenient and easy to use. Once opened the control is stable for 30 days at +2-8°C significantly minimising waste and helping to reduce costs.
Features & Benefits
- Liquid ready-to-use
- 100% human serum
- Assayed target values provided
- Stable for 30 days at 2°C – 8°C
| Description | Size | Analytes | Cat No | |
|---|---|---|---|---|
| Liquid CRP Control Level 2 | 10 x 1ml | 1 | CP2480 | |
| Liquid CRP Control Level 3 | 10 x 1ml | 1 | CP2481 | |
Analytes
- CRP
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CSF Quality Control
The Randox Acusera cerebrospinal fluid quality control is designed for use in the routine monitoring of both accuracy and precision on a wide range of instruments. Assayed method specific target values and ranges are provided for 11 parameters including percentage total protein quoted for electrophoresis regions at Albumin, Alpha-1-Globulin, Alpha-2-Globulin, Beta Globulin and Gamma Globulin.
Features & Benefits
- Lyophilised for enhanced stability
- Human based material
- Assayed target values provided for 11 parameters
- Stable to expiry date at 2°C – 8°C
- Reconstituted stability of 14 days at 2°C – 8°C
| Description | Size | Analytes | Cat No | |
|---|---|---|---|---|
| CSF Control Level 2 | 10 x 3ml | 11 | CF1500 | |
| CSF Control Level 3 | 10 x 3ml | 11 | CF1501 | |
Analytes
- Albumin (electrophoresis)*
- Alpha – 1- globulin (electrophoresis)*
- Alpha – 2- globulin (electrophoresis)*
- Beta- globulin (electrophoresis)*
- Chloride
- Gamma – globulin (electrophoresis)*
- Glucose
- Immunoglobulin G (IgG)
- Lactate
- Protein (Total)
- Sodium
*No claims are made regarding values or stability
Specific Protein Quality Control
The Randox Acusera Specific Protein quality control covers 26 serum proteins including immunoglobulins, complement proteins and inflammatory proteins. Designed for use in the routine monitoring of both accuracy and precision, assayed target values and ranges are provided for both immunoturbidimetric and nephelometric based methods. The liquid ready-to-use format is not only convenient and easy to use but eliminates the possibility of reconstitution errors.
Features & Benefits
- Liquid ready-to-use
- 100% human serum
- Assayed target values provided for 26 analytes
- Contains Total & Free Lambda Light Chains and Total Kappa Light chains
- Stable to expiry date at 2°C – 8°C
- Open vial stability of 30 days at 2°C – 8°C
| Description | Size | Analytes | Cat No | |
|---|---|---|---|---|
| Specific Protein Control Level 1 | 3 x 1 ml | 26 | PS2682 | |
| Specific Protein Control Level 2 | 3 x 1 ml | 26 | PS2683 | |
| Specific Protein Control Level 3 | 3 x 1 ml | 26 | PS2684 | |
| Specific Protein Control Level 1 | 6 x 3 ml | 26 | PS10221 | |
| Specific Protein Control Level 2 | 6 x 3 ml | 26 | PS10222 | |
| Specific Protein Control Level 3 | 6 x 3 ml | 26 | PS10223 | |
Analytes
- AFP
- Albumin
- a-1-Antitrypsin
- a-1-Acid Glycoprotein
- a-2-Macroglobulin
- ASO
- Anti-thrombin III
- b-2-Microglobulin
- Ceruloplasmin
- Complement C3
- Complement C4
- CRP
- Haptoglobin
- IgA
- IgE
- IgG
- IgM
- Kappa Light Chain
- Lambda Light Chain
- Lambda Light Chain (Free)*
- Prealbumin (Transthyretin)
- Serum Ferritin
- RF
- RBP
- Total Protein
- Transferrin
*Not for use in USA
Blood Gas Quality Controls
The Randox Acusera Blood Gas Quality Controls contain assayed target values for ten parameters, covering pH, pCO2, pO2, electrolytes, glucose and lactate. The material is provided in easy to open ampoules for added convenience and ease-of-use. The liquid ready-to-use nature of the control makes it ideal for use in point-of-care testing and on a wide range of blood gas instruments.
Features & Benefits
- Liquid ready-to-use
- Aqueous material
- Method specific target values provided for the most common blood gas analysers
- Suitable for use in POC testing
- Stable to expiry date at 2°C – 8°C
- Once opened controls should be analysed immediately for pH and blood gas parameters, for electrolyte measurements the control should be analysed within 1 hour of opening
| Description | Size | Analytes | Cat No | |
|---|---|---|---|---|
| Blood Gas Control Level 1 | 30 x 1.8ml | 10 | BG5001 | |
| Blood Gas Control Level 2 | 30 x 1.8ml | 10 | BG5002 | |
| Blood Gas Control Level 3 | 30 x 1.8ml | 10 | BG5003 | |
Analytes
- pCO2
- pO2
- Calcium
- Glucose
- Potassium
- pH
- Bicarbonate
- Chloride
- Lactate
- Sodium