Hearing Loss Linked with Common Household Products, Study Finds
Hearing loss is often associated with old age, tinnitus or balance disorders. However, studies show that anyone can be affected by hearing loss, at any age if exposed to a chemical present in many common household products.
Chances are, you take your senses for granted. Associated generally with deterioration in old age, we never assume we will go deaf or blind in our younger years. Nevertheless, approximately 3 million children in the USA suffer from hearing loss and this number is on the rise. (CHC, 2016)
In 2006, a study was released detailing the mysterious premature hearing loss of a collection of employees in a manufacturing site in Taiwan, specialising in adhesive materials. Chang, Chen, Lien, and Sung narrowed the phenomenon that was the loss of the worker’s auditory sense down to the responsibility of one chemical: Toluene.
Chemical-induced hearing loss, also known as “ototoxicity”, can affect anyone of any age and today, there are over 200 known ototoxic medications on the market known to cause damage to the inner ear containing chemicals largely known to induce ototoxicity such as Syrene and Xylene.
However, sold in many high-street shops, you’ll find the biggest player in the cause of ototoxicity: Toluene. Toluene is a major component of paints, varnishes, petroleum, printing inks, degreasers, adhesives, cigarette smoke, glues, thinners, and plastics. Exposure to Toluene, such as inhalation, ingestion or skin contact, is known to cause not only hearing loss, but commonly can be a factor in causing Tinnitus, Dermatitis, and vision impairment. In general, the component can wreak havoc for the central nervous system and prolonged exposure to high concentrations of the colourless liquid may result in loss of consciousness, and may even be fatal.
Wanisiusiow, whose findings were conducted using the RX series’ RX daytona and a Randox creatinine kit stated, “Toluene is undoubtedly one of the most widely used organic solvents in industry.” But how does Toluene do it? Wanisusiow goes on to state, “As far as we know, there are two major mechanisms which might explain toluene-induced hearing loss. Firstly, a poisoning of Deiters and Hensen’s cells, which are both important to maintain the K+ homeostasis in the vicinity of outer hair cells. Secondly, an oxidative cell injury, such as lipid peroxidation.”
An interesting point uncovered in this study is that suffering the severe side-effect of Toluene seems to be species-specific. The original experiment, carried out on rats, displayed expected symptoms of ototoxicity. However, guinea pigs reacted differently. The study speculates: The half-life of toluene is longer in the rat than in the guinea pig. This might be one way to explain the difference in cochlear sensitivity to toluene between rats and guinea pigs but likely not the only one.
So, what is it in the genetic makeup of guinea pigs, that rats do not possess, that could fight the negative effects of Toluene? Could learning what causes guinea pigs immunity be beneficial to our research into hearing loss?
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Dr. Peter FitzGerald honoured with Cathaoirleachās Reception in County Donegal
Our Founder and Managing Director, Dr. Peter FitzGerald, was this week honoured at a special Cathaoirleach’s Reception in Dungloe, Co. Donegal.
The reception, which was held in the Dungloe Public Service Centre on Tuesday 7th June, was hosted by the Cathaoirleach of Donegal County Council, Cllr Ciaran Brogan, to say thank you to Dr. FitzGerald for Randox’s job creation and investment in Randox Teoranta, Randox’s Donegal site.
Dr. FitzGerald established Randox Teoranta in Dungloe in 2008, as part of Randox’s global expansion plans. The facility currently employs around 100 people, with plans to increase this to 540 by 2020. Randox Teoranta is a highly innovative life-sciences, engineering, research and development and manufacturing centre playing a key role in realising Randox’s mission of improving clinical decision making worldwide.
Cllr Brogan said it was a great privilege for him to be in a position to honour Dr. FitzGerald with a special reception.
“Dr. FitzGerald’s accomplishments are immense, his contribution to the medical diagnostics sector, his commitment to continued research and development and his business acumen are testament to the work of a remarkable individual,” he said. “We are most grateful for his commitment to Dungloe and to County Donegal and to establishing a world class facility in our county, creating professional and highly skilled jobs in what is an exciting industry.
“Credit must also go to Údarás na Gaeltachta who have been strong supporters of this enterprise since it was established in Dungloe in 2008. Their ongoing commitment has seen Randox realise their vision of a world class research and manufacturing centre in Dungloe.
“By creating highly-skilled jobs, Randox now presents great opportunities for Donegal graduates living in other parts of the county and abroad to return to work in their own county.”
Dr. Peter FitzGerald, Founder and Managing Director of Randox, commented;
“I am incredibly grateful to Cllr. Ciaran Brogan, and to the team at Donegal County Council, for today’s event that recognises our commitment to County Donegal. Randox Teoranta in Dungloe is an integral part of our plans for Randox, a company committed to improving and saving lives through innovative diagnostics. Our scientists here are working on pioneering and life-saving research – world-class science that provides significant job opportunities for life scientists, engineers, software developers, and those in a range of associated manufacturing disciplines. We are excited by the potential of our Dungloe site in North West Donegal to transform the high value knowledge economy of the region.”
Also speaking at the event was Mr Seamus Neely, CEO, Donegal County Council CEO, Dr. Ciaran Richardson, Head of Randox Teoranta R&D, and Cllr. Marie Therese Gallagher, Donegal County Council.
Careers Tips | 5 Reasons You’ll Love Working at Randox
Are you thinking of working at Randox? Great! Whether you’re from a science background, business, or art, Randox embrace multiple disciplines and we, at Randox Careers, are here to give you 5 reasons why you’ll love working with us!
1. Company Culture
Randox have built a team of the most passionate, inspiring and motivated individuals in the industry. Employees of Randox aren’t just a team, but they’re family!
Randox Laboratories likes to celebrate talent, and encourages people to work to their strengths, as recently demonstrated in the largely successful Future in the Making event, which was held to gather and thank Randox employees worldwide for the success of the growth of the company. Randox encouraged employees to share their experiences through the hashtag #WeAreRandox. Check it out, here!
2. Learning Opportunities are Endless!
Due to the size of Randox, and the vast specialties in the health sector, Randox Laboratories has a lot to offer in teaching new, innovative techniques in business, science, design, technology, engineering, and many more!
Randox is a great place to be given the opportunity to get creative in your industry! Work is always fast-paced, forward-thinking and open to fresh, innovative ideas! Peter FitzGerald (Randox Founder & MD) stated “We never stand still here! Our mission is to transform healthcare by continuously improving diagnostic solutions, which, for us, ultimately means saving lives.”
Randox Laboratories is not only a great place to grow, develop and climb the career-ladder whilst in full-time work, but it encourages growth in students, too! Renowned for their highly active Placement programs for 1st and 2nd year students, Randox offers 50+ positions each year for every sector. We hold a special awards ceremony for our highest achieving students at the end of the year, commending them for their outstanding work at Randox! You can read about the Pinnacle Placement Awards and see this year’s winners here.
3. Randox is a Globally Respected Brand
Working for a company like Randox will prove your ambition to individuals in every industry globally. We understand your CV is very important to you, and having worked for a well-respected brand like Randox, you’re sure to stand out from the crowd!
4. Be a Jet-setter!
Randox has a large global presence. With offices in over 145 countries, we are frequently attending high profile events in such places as Dubai, Thailand, London, USA, and Paris! (You can check out some of our upcoming events, here.)
You can have the opportunity to experience these beautiful countries with Randox!
5. Let Your Work Change The World
Randox is an influential company and a global leader in the Healthcare and Diagnostics industry, responsible for diagnosing 5% of the population’s conditions. We are dedicated to improving the healthcare industry, and saving lives with our hard work. Randox’s success means better quality of life for the global population, as we discover how to diagnose as early as possible.
Do you want to change the world with us? Join the team, check out our opportunities!
Careers Tips | Simple Tips to Prepare for That Dreaded Presentation!
Have you been asked to make a presentation as part of a job interview? No need to worry!
The word “presentation” can strike fear and panic into anyone, but you can overcome a mild case of Glossophobia in just 6 simple steps!
1. Find Your Technique!
Everybody’s different. Therefore, no one’s preparation or presentation techniques are the exact same. There are plenty of ways for preparing for presentations. To determine your perfect technique, you need to identify your problems. Get some feedback from peers if you’re not sure! After this, you can use your problem-solving skills to try and find a solution. For example, if you find you panic when you forget words and sentences, learn a much “looser” version of your presentation. Learn your slides back to front, but leave the verbal message up to improv! This may be a much better technique to convey passion, if you know your topic well.
2. Communicate a clear message
One of the main reasons you are making this presentation is to communicate a particular subject or field. Make sure that you know what you’re talking about and focus on the topic at hand. It will make you come across more focused in the eyes of the interviewer.
3. Practice!
Practice, practice, practice. When you are conducting a presentation that hasn’t been practiced, it’s obvious. Take some time to prepare your presentation beforehand so you have more time to practice. Practice in front of others, they’ll be able to give you feedback to improve your presentation in a way you’ve never thought of before! The more you practice, the more familiar you come with you presentation which will help you eliminate your nerves!
4. Do your research
There’s nothing worse than a candidate making a presentation who hasn’t done their research on the company. Have a look at the company website, read up about the products they sell and the events they take part in. This will impress the interviewers as it looks like you care about the company you’re applying for and that you want to be a part of the organisation.
5. Watch your timing
The last thing you want to do in your presentation is have your interviewers fall asleep. If you feel like you have too much information to get across in a short space of time, don’t worry – it’s better to keep it shorter and more interesting than bombard them with information. Less is more, so a helpful rule to follow when making a presentation is one slide per minute.
6. Deep breaths
Nerves before a presentation are completely normal. Arrive early, drink some water and take deep breaths to calm yourself down. Just remember that pressure can help you perform well!
Thanks for reading, and good luck!
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University Students Reaching Dizzy Heights at Randox
Randox recently celebrated the contributions of its placement students at the annual Randox Pinnacle Placement Awards.
At Randox we work closely with a number of universities throughout the UK to support the professional and personal development of students, by providing work placements in our world-leading Engineering, Science and Business departments.
Students, past and present, have come from far and wide to work at Randox – from universities such as Queen’s University, Ulster University, St Andrew’s, Strathclyde, Imperial College London and University of Brighton.
This year, at the 2016 Randox Pinnacle Placement Awards, the top three students within each discipline have been rewarded for their outstanding contributions and this week were presented with certificates of merit and prizes to mark their achievements.
Receiving special recognition for his work was 21 year old Dean McGonagle from Limavady. The Aerospace Engineering student from Queen’s University, was awarded the Best Overall Placement Student, for his valued contributions to Randox.
Dean redesigned the Biochip storage module on Randox Evolution machines, and the changes he made are now being implemented into production analyser machines across the company.
Receiving his award Dean McGonagle said:
“I have really enjoyed seeing my designs actually being used within the Evolution analysers and how that is having a positive impact on the business. A particular highlight of my placement year was getting to travel to England to observe the shipping crate I had designed for the Evolution undergo environmental and distribution testing. I have really enjoyed my time at Randox, I’ve been involved in many different projects and have received lots of help and guidance from the great engineering team here.”
Congratulating Dean and his fellow placement students, Linda Magee, Head of Human Resources at Randox said:
“At Randox we are great advocates of a placement during a student’s time in education. In a company such as Randox, with operations on a global scale, the student is provided with some very valuable work experience in their discipline. It’s not just the student who benefits – we have the pleasure of working with a dynamic generation of students who bring with them extremely fresh and forward-thinking ideas.”
The top students in the Randox Pinnacle Placement Awards were:
Engineering
- Dean McGonagle, Queen’s University Aerospace Engineering – Mechanical Design Team at Randox
- Jordan Thomson, Ulster University Computer Science – Software Team at Randox
- Marc McKee, Queen’s University Mechanical Engineering – Mechanical Design Team at Randox
Science
- Christopher McNally, Ulster University Biomedical Science – Immunoassay Development Team at Randox
- William Heasley, Ulster University Biomedical Science – Biochip Customer Unit Team with Philip Holmes
- Kathryn Watt, St Andrew’s University Medicinal Chemistry – Synthetic Chemistry Team at Randox
Business
- Meghan Semple, Ulster University Marketing – RX Marketing Team at Randox
- Fearghal Savage, Ulster University Information Technologies – IT Enterprise Support Team
- Michael Boyle, Ulster University Interactive Multimedia Design – Graphic Design Team at Randox
The incoming 2016-17 academic year marks the highest intake of placement students for Randox, with over 70 students starting in the company over the next few months. Anyone interested in applying for the 2017-18 scheme should email recruitment@randox.com.
RX modena – Enquiry
The All-new Clinical Chemistry Analyser from Randox’s The RX series
Randox employee hosts bake sale in aid of the Cystic Fibrosis Trust
Randox employees enjoyed a bake sale yesterday at our headquarters in Crumlin. The bake sale was hosted by Randox employee Rachel Walls on behalf of her sister, Ursula McKenna, who will be running both the Dublin Marathon and Manchester half Marathon later this year in aid of the Cystic Fibrosis Trust.
Ursula McKenna has raised an impressive £3000 for the Cystic Fibrosis Trust and is set to continue her efforts in raising money for this great cause. Having run the London Marathon twice, with the last one completed on Sunday 24th April, her motivation stems from personal empathy of the condition;
‘Our cousin suffers from Cystic Fibrosis, and running a few marathons is easy compared to what he has to deal with on a daily basis’
Cystic Fibrosis is a genetic condition caused by a faulty gene that controls the movement of salt and water across the cell wall. This causes mucus to build up in the lungs and digestive tract, causing problems with breathing and digestion. An estimated 1 in 2,500 babies born in the UK have Cystic Fibrosis, with more than 2.5 million people in the UK carrying the faulty gene. Currently there is no cure for Cystic Fibrosis, however there are treatments to help manage the symptoms.
Ursula’s dedication to the cause is evident and this extends to her family through their help and support. The bake sale hosted by Rachel yesterday at Randox included scrumptious treats made by the family, and helped raise £308! In addition to hosting fundraising events, her brother also ran the New York Marathon in 2014 and will be joining Ursula in running the Dublin Marathon in October. Hoping to beat her previous completion times of 4:27 in her first marathon and 4:07 in her second marathon, Ursula aims to complete the Dublin Marathon in less than 4 hours. Good luck!
Grand National Sponsor Randox goes back to its roots with Point-to-Point Racing Event
Global healthcare company Randox, recently unveiled as the main sponsor for the Grand National under the banner of Randox Health, is committed to supporting local grass roots horse racing, as this weekend it hosts the Point-to-Point Steeplechases at Crumlin, County Antrim, in association with the Killultagh, Old Rock and Chichester Hunt.
Point-to-Points are now firmly established in national hunt racing, with several champion horses starting their careers on the Irish Point-to-Point circuit.
Following the Randox Point-to-Point 2014, Classic Place was sold to Gigginstown House Stud, owned by Ryanair’s Michael O’Leary, who we all know to be the owner of The Crabbie’s Grand National 2016 winner, Rule The World.
Last year multiple All Ireland Champion Derek O’Connor registered a double, partnering Ballycross to victory for Templepatrick trainer Colin McKeever and leading local owner Wilson Dennison, followed by Chosen Dream at the fifth. O’Connor also recorded a brace of winners having scored with Sister Saragh at the first and Frost at the fifth.
But don’t worry if you’re not a racing enthusiast – the Randox Point-to-Point is the perfect day out for all the family. The increasingly popular event will host a unique Artisan village, showcasing a variety of food, drink and crafts stalls including, homemade jams, chutneys and sauces, ceramics, handmade chocolate and jewellery, woollen knits, handmade tea towels and tote bags, cakes, photography and much more!
Randox Managing Director, Dr Peter FitzGerald, highlighted the company’s equestrian heritage and is looking forward to both this year’s Point-to-Point, and next year’s Grand National:
“We are pleased to host the Point-to-Point with the Killultagh, Old Rock and Chichester Hunt, where champions are made. As a global company with firm links to our local heritage, we are proud to be involved with grass roots equestrian sports, which are part of the local community and sports scene. This history of being involved in equestrian events has naturally progressed to our sponsorship of the Grand National, and is fitting with our ambition. We look forward to this year’s two day Point-to-Point – where we might spot a future Randox Health Grand National winner!”
The Randox Point-to-Point will take place on Friday 22nd and Saturday 23rd of April, at Largy Road in Crumlin. The first race on Friday 22nd of April will start at 4pm; on Saturday 23rd of April, the first race takes place at 2pm.
General admission is £5 per person, with free entry for children under the age of 16.
Admission via the Laurelbank, Largy Road Crumlin, BT29 4RN.
Craft stalls are provided by North Down Crafts Collective and The Prince’s Trust charity.
For more information on the Randox Point-to-Point, email events@randox.com
Randox named in The Sunday Times Profit Track 100 League Table
This week saw the publication of The Sunday Times Profit Track 100, and we are delighted to announce that Randox has been named at number 65 in the league table which ranks the 100 private UK companies with the fastest-growing profits over a three-year period.
Stuart Lisle, of BDO Accountants, featured Randox in his piece; ‘Innovation and trade make a good formula for expansion’, noting impressive findings that:
- Randox supplies 10% of the world’s cholesterol tests
- Our diagnostic products are used in 145 countries across the globe
Stuart Lisle commented;
“After outperforming most of our peers, Britain is entering a period of economic uncertainty: stock markets are volatile, growth in China is slowing, Europe’s recovery has stalled and, as the Bank of England governor Mark Carney noted in March, the possibility of Brexit is not helping. Our polling shows that 70% of mid-market companies think leaving the EU would make running their businesses harder but there are strong arguments on both sides of the debate.
Thankfully, while our politicians talk in Westminster, our mid-market companies are getting on with business, driving growth by innovating at home and trading overseas.
This year’s Profit Track 100 contains numerous examples. Just look at what Peter FitzGerald, founder of Randox Laboratories is achieving. From humble beginnings in his parents’ garden shed in County Antrim, Northern Ireland, he has developed the firm into one the supplies 10% of the world’s cholesterol tests as well as a range of other diagnostic instruments used in 145 countries…and it is one of 55 companies in this year’s Profit Track 100 that are growing by selling internationally.”
We would like to thank Stuart for recognising our success and innovation. We are extremely proud of how far the company has come – from humble beginnings over 34 years ago, to a company with more than 1400 employees of 44 nationalities, including 300 research scientists and engineers.
Dr Peter FitzGerald, Managing Director of Randox said:
“The growth that we have witnessed over the last 3 years principally enables us to further strengthen our infrastructure and increase the world leading research and development we are conducting – to achieve the earliest possible diagnosis of a very wide range of clinical conditions. We remain dedicated to saving lives and improving health worldwide, and reinvesting our profits helps ensure that we will realise our vision.”
The Profit Track 100 league table is compiled by Fast Track, the Oxford-based research and networking events firm.
Gestational Diabetes: The Third Kind
Year upon year, WHO (World Health Organisation) have set a date to raise awareness of various health issues from Food Safety, to Hypertension to Vector-Borne diseases. This year, WHO are setting their goals in raising awareness on Diabetes; those with family and friends affected and those diagnosed. The RX series take a closer look at a type of Diabetes we don’t often talk about to raise awareness for the #BeatDiabetes campaign by the World Health Organisation (WHO).
Diabetes is a life-long condition, featuring in the top 10 causes of death globally, responsible for approximately 1,497,371 deaths worldwide and 6,088 in the UK alone yearly. As a major non-communicable disease, diabetes claims on average around 8% of total health budgets in developed countries.
As many know, diabetes can come in 2 common forms: Types I Diabetes; where the pancreas does not produce insulin and Type II Diabetes; where the pancreas doesn’t produce enough insulin/the body’s cells do not react to insulin. Not very often, however, do we hear the term Gestational Diabetes.
Gestational Diabetes is a type of diabetes that affects pregnant women, usually in their third trimester. The good news is, the condition usually disappears soon after the baby is born, but what are the risks, how serious is it really and what are the chances you may find yourself dealing with the condition?
Pregnancy puts extra demands on the body, as it demands higher level of nutrition, and energy. Gestational Diabetes (GDM) occurs when the body can’t produce enough extra insulin to meet these demands.
The condition is surprisingly common, with 15% of all pregnancies resulting in the mother suffering from GDM. Whilst it only occurs in pregnancy; it is estimated that over 50% of women who have had gestational diabetes will go on to develop type II diabetes within 5-10 years of delivery which is a startling statistic.
A study carried out at JSS Medical College aimed to investigate the biochemical parameters that could be used to diagnose GDM. Levels of serum creatinine, uric acid and the albumin were studied in GDM patients and unaffected pregnant women to consider any correlation between these biochemical markers and certain clinical parameters. The RX daytona, a clinical chemistry analyser from Randox’s RX series range was used to analyse the samples. The conclusion was that biochemical parameters such as serum creatinine, uric acid and albumin, can help in predicting the early onset and progression of GDM.
The study also stated that early diagnosis was paramount as it could help in the proper treatment of gestational diabetes and its associated complications for mother and baby, thus helping to improve the quality of life of the GDM patients and their offspring.
There are measures women can take before and during pregnancy to prevent the likelihood of Gestational Diabetes occurring. One study shows that increasing fibre intake to 10g per day reduces the risk by 26%. Also, women who exercise before pregnancy have a lower risk of gestational diabetes, the more intense the exercise, the lower the risk. However, this doesn’t have to mean extremely strenuous exercise, anything as simple as walking at a brisk pace, rather than at a leisurely pace will reduce your risks.
This year on World Health Day, we urge you to share your stories and give support for those affected by diabetes and use the hashtag #BeatDiabetes to get involved with the conversation.
Randox offers high quality tests for the diagnosis of diabetes and the monitoring of its complications.
To find out more about the RX series range of clinical chemistry analysers and how we tackle Diabetes with accurate and early diagnosis, take a look at our brochures below.
Questions? Speak to the RX team: theRXseries@Randox.com
