We Are Randox | Randox Scientist Marta Crudden inspires the next generation of scientists at St. Bride’s Primary School
We Are Randox | Randox Scientist Marta Crudden inspires the next generation of scientists at St. Bride’s Primary School
As a world-leader in diagnostics, dedicated to improving the health of populations across the globe, we know the importance of inspiring and nurturing the next generation of scientists who will carry on our hard work and strive to realise our vision.
Our scientists at Randox are all equally passionate, knowledgeable and experienced, and as such often make visits to schools, universities and colleges to spend time with students interested in asking our team about what it’s like to work in a global healthcare company.
This month, Marta Crudden, an R&D Scientist in our Serum Production Team, paid a visit to St. Bride’s Primary School in Belfast, to spend the day with the pupils there and showcase what a career in science has to offer.
Marta commented;
“When I was offered the opportunity to speak at St. Bride’s Primary School I jumped at the chance, because I am passionate about encouraging school children to pursue a career in STEM. I have a Biomedical Degree from Queen’s University and also spent 5 years there conducting cancer research, so science has played a big part in my life.
“I was delighted to be able to share my experiences with the children, who were very interested in what I had to say. It was very enjoyable listening to and answering their imaginative questions, and I particularly enjoyed the presentation I gave to the pupils on DNA, because they were all incredibly curious and eager to learn more.
“They were fascinated to hear that all cells, not just humans, have DNA, and therefore were throughly attentive when we moved on to our interactive session on DNA. During this session I showed them how to extract DNA from strawberries and what it really looks like in a real organism.
“This prompted a lot of interesting questions about cloning animals, including dinosaurs! There is nothing quite like the imagination and curiosity of children!
“A few days after my day at St Bride’s I received a number of messages from some of the parents saying thank you for my talk, and for inspiring their kids to become interested in science.
“I like to think that some of those children will go on to choose STEM subjects when they go to highschool, and could even end up working here at Randox! I’m delighted to have been able to share the work we do with the next generation of scientists.”
For more information on how Randox promotes STEM careers within schools and universities please contact randoxpr@randox.com
Visit the Randox Teoranta Open Morning to find out what you will do in 2017
This Christmas we are issuing a challenge to life scientists, engineers, software developers and software testers.
As we celebrate the achievements of our team at Randox Teoranta in Dungloe, Donegal during 2016, we are asking potential employees, “What will you do in 2017?”
Our team of scientists, engineers, software developers and software testers at Randox Teoranta work in state-of-the-art facilities on pioneering research, developing innovative and revolutionary technologies that save lives, through earlier and more accurate diagnosis.
In 2016:
- Tara’s scientific team developed a revolutionary test for Alzheimer’s disease.
- Darren engineered new technologies with the ability to detect disease and save lives.
- Maryrose’s team designed drugs testing software to be used by police officers in criminal investigations.
And in 2017 our team will continue to work on cutting-edge research for key health issues including kidney disease, thyroid disease and gastro intestinal disorders.
What will you do in 2017?
If you want to truly make a difference to global healthcare in a team of the best and brightest scientists, engineers, software developers and testers then join us at the Randox Teoranta Open Morning on Friday 23rd December.
Our world-class research, development and manufacturing site in Dungloe offers unrivalled opportunities for graduates and those with industrial experience within:
- Life Sciences
- Mechanical, Embedded and Medical Device Engineering
- Diagnostics
- Software Development and Software Testing
Ciaran Richardson, Head of R&D at Randox Teoranta, commented;
“Our investment in this facility provides highly-skilled job opportunities for life scientists, engineers and software developers, and with such fantastic career opportunities available there’s real room to establish a world-class career in the thriving biotechnology industry.
“The transformative work we’re doing here in our next-generation science and engineering facility is truly ground-breaking so for those who want an unrivalled, challenging and rewarding career, they need look no further than Randox Teoranta.”
On our Open Morning you will have the opportunity to meet with current Randox members of staff, take a tour of our ultra-modern facilities and ask all the questions you’ve ever wanted to know about Randox Teoranta.
We look forward to seeing you there.
Randox Teoranta Open Morning
Friday 23rd December
09:00 – 11:30
Address: Randox Teoranta, Meenmore, Dungloe, Co. Donegal.
Tel: +353 7495 22600
Email: randoxpr@randox.com
Randox Health launches international roll-out of clinics with official opening in Holywood
The most innovative health clinic in Northern Ireland has been officially opened by the First Minister, the Rt. Hon. Arlene Foster, who described Randox Health Holywood as “an example of what belief, commitment and inspiration can achieve.”
With over 34 years’ experience in developing accurate and cutting-edge blood science technology, and an investment of over £225 million in Randox’s patented Biochip, Randox Health brings the world’s most advanced and personalised Health Programme directly to the public. Randox are rolling out additional clinics across the country including in Liverpool and Manchester before the launch of the Randox Health Grand National, and internationally including Dubai and in the USA.
The flagship centre features Randox’s revolutionary ‘Evolution’ blood screening machine, the first of its kind in any Randox Health laboratory. Capable of delivering accurate results from more than 2600 tests an hour including, but not exclusive to, cancer surveillance, fertility, heart, nutritional, digestive and diabetes health. Randox Health technology creates a full body health profile designed to spot illness even before it becomes symptomatic; empowering patients to take preventive action to stay healthy.
The First Minister Arlene Foster said;
“Randox occupies a special place in Northern Ireland. For almost 35 years, it has been a global leader in medical diagnostics. Dr Peter FitzGerald has dedicated himself completely to improving people’s health around the world, and we see the results of that here in this clinic, which I am delighted to open to the public. I fully embrace his philosophy of preventive health and doing what we can to stay healthy, living fuller lives for longer.”
Dr Peter FitzGerald said;
“Right across society, I see too many people struggling with preventable illness. Conditions like Type-2 diabetes, described as the fastest-growing epidemic of our time, are having a catastrophic impact on people’s lives. Cutting our risk of becoming sick is crucial, and the more we know about the state of our body, the better. I believe there needs to be a fundamental shift in the way we look at our health, with an emphasis on protecting it. We’ve developed the latest in blood science technology and using our expertise through these clinics, you can obtain all the information you need to stay well now and throughout your life.”
Make sure to follow Randox Health on Twitter (@RandoxHealth) Facebook (www.facebook.com/RandoxHealth) and Instagram (@randox_health).
For more information about the official opening of our Randox Health Holywood Clinic please contact randoxpr@randox.com
QC Shelf Life – Why is it Important?
An important consideration when choosing your Quality Control material that is often overlooked is the shelf life of the control. With every new lot of control extensive validation studies must be performed. Regulatory bodies such as CLIA require new lot numbers to be evaluated before routine use in the laboratory. For example, CLIA has instructed that any new control lot to be run alongside patient samples will need to be verified alongside the old lot of control. The process is designed to give laboratory professionals confidence in the new material and ensure it is fit for purpose before implementing it in the lab.
As part of the validation process laboratories are required to assay both the old and new lots side by side. The current lot is then used to help verify if the new lot will be acceptable to run within the lab. Such validation studies can be very costly for a lab as well as being extremely time consuming – with some studies taking up to a month to complete! By choosing a control with a longer shelf life laboratories can aim to use the same lot of control for a longer time period. Ultimately this means fewer lot changes and minimal inconvenience for the lab. With a shelf life of 2 years for liquid controls and up to 4 years for lyophilised, coupled with unrivalled stability claims, employing Randox Quality Control in your laboratory will ensure that expensive lot changes will be a thing of the past. Our comprehensive control offering is guaranteed to increase efficiency and reduce costs in any laboratory without compromising on quality.
Contact us today to find out more information on our Acusera range of Quality Controls.
Randox launches Chinese market growth initiative in Shanghai
Following 18 months of extensive market research and infrastructural developments, global healthcare diagnostics company Randox Laboratories has this week launched a new market expansion programme in Shanghai in China, to help develop and strengthen business relationships and increase exports.
To mark the roll out of the initiative, Randox is hosting a conference in Shanghai for its most recently acquired distributor networks, who will benefit from training on Randox’s latest healthcare technologies, designed to facilitate early and accurate diagnosis to improve patient outcomes.
Susan Hammond, Global Product Manager at Randox Laboratories, commented on Randox’s Chinese expansion plans at the company’s Shanghai training conference;
“China is one of our most important markets and we have been exporting our world-class diagnostic products there for over 20 years. With increased output from our innovative R&D programmes, and enhanced manufacturing capabilities, including new facilities at Randox Science Park, we have an increasing range of high quality products, which are in demand in growing and dynamic markets such as China. We are now actively growing our market presence in order to improve our penetration and subsequent support to customers.”
As well as providing education on the latest diagnostic developments to conference attendees, Randox are also hosting over 300 guests at Camerata Ireland Concerts in Shanghai, Beijing and Wuhan over the coming week. Randox are Global Sponsors of Camerata Ireland and are delighted to showcase to Chinese audiences not only the science and innovation that come from our shores, but also the breadth of cultural talent.
Susan continued;
“Our infrastructural changes within the Chinese market have been in planning and development for the last 18 months and we are delighted that our support of the talented Camerata Ireland orchestra on their Chinese tour this month gives us the opportunity to visit key business partners while simultaneously supporting our young musicians in their careers.”
The Camerata Ireland Orchestra, whose joint patrons are Michael D Higgins, President of Ireland and Queen Elizabeth II, begin their tour on the 9th December in Shanghai, when the all-Ireland orchestra will perform a diverse tapestry of classical music, led by Camerata Ireland founder and 1986 Tchaikovsky International Piano Competition Winner Barry Douglas.
Barry Douglas, Founder and Artistic Director of Camerata Ireland said;
“Following a successful tour in China last year we are delighted to be back, and it is particularly special for our Solo Flautist Eimear McGeown as this tour marks her Chinese debut. On behalf of everyone in Camerata Ireland I would like to take this opportunity to thank our global sponsor, Randox, without whom our international touring would not be possible. We are delighted to be able to work together across the world to showcase our musical and business talent to a global audience.”
The Camerata Ireland tour of China is as follows: Friday 9th December in The Shanghai Grand Theatre in Shanghai, in the Forbidden City Concert Hall in Bejing on the 10th and for the final installment of their China tour, Camerata Ireland will perform in the Wuhan Qintai Concert Hall in Wuhan.
For more information about the launch of our Chinese market growth initiative, please contact randoxpr@randox.com
We Are Randox | Randox Teoranta get in the Christmas Spirit with Team Hope Christmas Shoebox Appeal
‘Tis the season of giving! And our team of scientists, engineers and office staff at Randox Teoranta, in Co. Donegal, Ireland have embraced this wholeheartedly, by getting involved with the Team Hope Christmas Shoebox Appeal.
For the past 18 years Team Hope, a charity based in Ireland (with the help of businesses, schools, and individuals) have delivered Christmas shoebox gifts to over three million children in some of the remotest and poorest parts of the world.
Many of these children’s families have to survive on less than €1 a day.
Those who get involved with the Team Hope Shoebox Appeal bring a ray of hope and joy to children who think they’ve been forgotten about at Christmas time.
Last year, 212,002 people across Ireland got involved with the Team Hope Shoebox Appeal, and this year, we are extremely proud that our Teoranta team took the time to fill an incredible 54 Christmas shoeboxes.
The team filled their boxes with gifts and useful items for the children, who will open their boxes on Christmas Day to find the wonderful surprises waiting for them inside!
These ranged from items for school like a pen, pencil, book, colouring pencils or calculator, to hygiene items such as toothbrush and toothpaste, soap, a facecloth, hairbrush and comb, plus clothes including hats, scarves, gloves and socks.
Finally, the staff made sure to include an extra special little something for each child to open up on Christmas Day! These included games, sweets, musical instruments, cuddly toys and skipping ropes.
Each box was then carefully gift wrapped with care in festive Christmas wrapping paper.
Claire Newbon, Manufacturing Operative, introduced the Showbox Appeal to Randox Teoranta and found that everyone was really keen to get involved.
“Within the team here at Randox Teoranta we are all very fortunate to have great jobs, loving families and a roof over our heads. But we are very aware that there are adults and children in other parts of the world who aren’t so lucky, through no fault of their own.
“At the most joyful time of the year, the Teoranta team wanted to be able to share the magic of Christmas with those children who would otherwise not get any presents.”
Katie Sweeney, Randox Teoranta Receptionist who co-ordinated the Shoebox Appeal Project for the team, added;
“Our boxes were collected by members of Team Hope and it is lovely to know that they will be opened by children less fortunate than us across the world. Staff in each department really got involved and we’re really proud of our achievement of creating over 50 boxes. Each box will make Christmas that little bit better for a child so we’re glad to have been able to help in some way. Merry Christmas to all the children who are helped by Team Hope, and of course to everyone at Team Hope for the fantastic work they do.”
For more information about how Team Teoranta got involved in the Team Hope Christmas Shoebox Appeal, please contact randoxpr@randox.com
Children at increased risk of drug-resistant infections after taking antibiotics
Children who are prescribed antibiotics are 12 times more at risk of acquiring drug-resistant infections in the weeks afterwards, according to a leading public health figure.
Public Health England medical director Paul Cosford told the Science and Technology Committee this week that the risk is greater for younger people than it is for adults.
“We’ve got good evidence that if you or I have a course of antibiotics now, within three months our risk is three times to get a resistant infection of some sort because we’ve had the antibiotics affecting all the organisms in our bodies. If you’re a child you’re 12 times more likely to get a resistant infection in the three months after a course of antibiotics.”
Whilst acknowledging that the drugs do a have part to play, Cosford stressed this had to be done correctly – and compared antibiotics to “using a pesticide in a rich woodland.” At the same time as tackling the harmful infection the drugs will destroy useful bacteria in the gut.
The information was taken from two major reviews on the routine-use of antibiotics in primary care, and he said the results underline the importance of continued efforts to decrease prescription rates.
“There is a growing body of evidence that taking antibiotics makes it more likely that your next infection will be a resistant one, so prudent use of these life-saving medicines is essential.”
One review looked at children who had urinary tract infections and found that they were more than 13 times more likely to have contracted drug-resistant strains if they had been given antibiotics in the previous six months.
The 2014 Longitude Prize survey of antibiotics in primary care revealed that 90% of British GPs felt pressure from patients to give out the drugs, and almost half had done so knowing it would not treat the patient’s condition.
Mark Woolhouse, Professor of Infectious Disease Epidemiology at Edinburgh University told The Guardian that the consequences of antibiotic resistance required a global plan, just as with climate change. However he added that, “In terms of the threat to my own health, and that of my children, and my family’s health, I am much more concerned about antimicrobial resistance than I am about climate change.”
Randox is supporting the battle against antibiotic resistance. Our wide range of related products includes our Respiratory Multiplex Array which tests 22 common virus and bacteria pathogens can detect whether an antibiotic should be prescribed.
John Lamont, Chief Scientist at Randox Laboratories, whose team developed the molecular test, commented;
“Current diagnostic testing for respiratory infections takes at least 36 hours to confirm the nature of an infection, and they cannot name and categorise infections as bacterial or viral in the way that our respiratory test can. C-reactive protein tests, for example, that are currently in use can only indicate whether a bacterial infection is likely. We need more than just guess work to combat the antibiotic resistance pandemic.”
For more information, please visit http://www.randox.com/respiratory-multiplex-array/ or contact RandoxPR@randoxcom
On the journey to the Randox Health Grand National…Rule The World returns to Mouse Morris’ stables in Tipperary
On a crisp and sunny winter morning in the County Tipperary countryside, Grand National 2016 winner Rule The World returned to the busy stables that prepared him for his victory over Aintree’s fences.
Trainer Mouse Morris had not seen his winning horse since he made the decision to retire him earlier this year, and so the launch of the Randox Health Grand National 2017 was an emotional reunion for all involved.
Winning jockey David Mullins was also there to welcome back his Grand National partner. His win with Rule The World was a fantastic introduction to the world’s most famous race – a victory on his very first attempt!
And the team from Everardsgrange Stables in Fethard fancy their chances at another Aintree victory – this year entering three horses in the Randox Health Grand National, including Irish Grand National winner Rogue Angel.
Morris explained;
“There is no point in sleeping if you don’t dream. To win the Grand National with him would be a dream come true.”
Stuart Penrose, Global Marketing Manager for Randox, was excited for the journey to the Randox Health Grand National 2017 to begin;
“The Grand National is a massive race right across the world, and this year the teams expect the new broadcaster ITV will deliver an audience in excess of 12m. While we’re a global leader in the business world, we are now launching ourselves as a company with direct interaction with the public through our Randox Health clinics and we couldn’t have picked a better way to broadcast our message. We are extremely happy.”
Eamon Lenehan, Global Marketing Manager, commented;
“It is truly one of those events that transcends the sport. I think what really resonated with us is that it is known as ‘The People’s Race’, and so our commitment to improving people’s lives through health is a great fit.”
While the race is so accessible, its popularity and wonder also lies in its unpredictability. Rule The World, a horse who’d been carefully brought back from a twice fractured pelvis, won the race in 2016 as a maiden over fences.
John Baker, Aintree Managing Director, rounded off a wonderful day at Mouse Morris’ yard by saying;
“Hopefully we can write some more history next year.”
Listen to the full interviews with Mouse Morris, Eamon Lenehan, Stuart Penrose and John Baker, with Racing Journalist Dave Keena below!
For more information about the Stable Visit, please contact randoxpr@randox.com
We Are Randox | Randox Artist-in-Residence Joe McGuinness on his passion for art, his love of drawing and his plans to release a second novel
Through our We Are Randox stories we aim to showcase all our employees’ skills and talents and with a dedicated workforce of over 1400 people we are always spoilt for choice!
This week we sat down with artist Joe McGuinness, who joined our team only six weeks ago, to hear all about his passion for art, his love of drawing and his plans to release a second novel.
“I was about seven years old when I first realised that I was going to be an artist. I remember my mother was pregnant with my baby brother, she was unwell and I found her curled up on our sofa. So I went and got some paper and a pencil and decided that I was going to draw a portrait of her. To this day I can still remember the expression on her face when I showed her the finished piece. It was her reaction and the look in her eyes that kicked me off and I knew in that exact moment that art was going to be a big part of my life.”
As Joe went on to study Art and Design for three years at the Rupert Stanley College located in Belfast he found himself more interested in learning about the history of artists’ lives and what inspired them to produce art.
“I love the works of Paul Gauguin, Paul Cezanne and Vincent Van Gogh and I am fascinated by his life. There has been many an afternoon where I have just sat down and looked up as many channels as I can to find out more about him and how he lived. Similarly to Van Gough I tell a story or a personal journey that I have been on through my art. I do have an emotional connection to some of my art, they mean a lot to me and I wouldn’t part with them.
“My favourite piece is a piece called “Lock and Key.” There is a lock and a key hidden in the picture and I will only reveal where it is to the person that I pass it on to.”
“It’s great when I get to barter with my art.”
“I was once asked to do a painting of a friend’s house up in Donegal. So I said I would if they gave me the keys of the house so I could go up and stay in it for a week in August with my wife. There was another occasion when I was asked from a friend of a fella originally from County Antrim if I could reconstruct an old dwelling that he grew up in. It turned out he was a multi-millionaire who is now about 90 years of age living out in New Zealand. Sometime after I had sent the painting to New Zealand I received a letter back from his wife. She said when he first saw the picture he cried. It’s now his pride and joy, and has been placed in his study where he sits and looks at it. I find that incredible and that’s what makes me glad that I am an artist.
“I like to draw while I’m away on holidays, I find that I can relax in the good weather and just sit and draw. I remember back when I was in Milan, there was this little fountain spouting water. It wasn’t famous or of much interest to the passers-by but I thought it would make a beautiful picture. So I sat down and started to draw it when a gentleman came and asked could he join me. It turned out that he was a professional photographer from Paris and loved my art work. It’s great when you can make friends out of something that you love. “
“Through my art I have met a range of friends all over the globe, from France, to Rome, Sicily, Milan, Australia, it just goes on.”
“Most Saturdays you can find me downstairs in the Conway Mill. I sit and draw next to where my artwork is displayed and people sometimes like to look on and watch while I’m drawing. My favourite type of medium to paint with is acrylics but I can teach a range of different techniques. Wax etching is a beautiful technique which I learnt whilst I was studying art. Sometimes people stop and ask me questions about my pictures or about certain techniques and I would invite them back the following week to join me.”
“In my first ever exhibition I sold about 90% of my work.”
“It feels incredible to say that my art has been bought by people all over the world from New York, Europe and as far as Australia. The great-great niece of the famous Ned Kelly has some of my work. I have also donated work to Autism New York to help raise money for autism which is a cause I am very passionate about.
“In the future I would like to get more involved in the design aspect of art. I have been asked if my drawings could be used for prints for duvets covers and also for pottery and vases which would be great so I’m going to start looking into that. I’m also currently looking at property in Alvor in Portugal- that’s where I want to be in nine years’ time. My hope is that I can retire there and open up my own art academy. There is nothing greater than a group of artists sitting together and talking art and learning from each other. I’m also working on some illustrations for my second book that is based on events that have happened throughout my life. I think it will be a much deeper Joe than what you got to read about in my first book, ‘Rainbow over the Black Mountain’.
“My wish for the future, when I’m gone is for museums across Ireland – north and south – to have their pick of my art collection. In some of my paintings that I sold I have hidden letters inside the frame explaining the inspiration behind the painting, just to add that little extra personal touch to them. Sure you never know, in a hundred years’ time someone might find some of my letters… now wouldn’t that be a story worth telling!”
**Joe would like to offer a special thanks to Maureen Shields (Supervisor) and Cathy Hurrell (HR) and to the rest of Randox staff and employees. Following Joe’s time with us he added “You’re a great bunch of people.” **
Thank you Joe for spending the time to discuss your art work with us. We can’t wait to read your second novel and see all the wonderful images that will come with it.
For more information about our wonderful mulit-talented team here at Randox, please contact randoxpr@randox.com
Randox Diagnostics: Leading the Field in Equine Health
We wouldn’t be the experts in Equine Health we are without our team of highly knowledgeable and experienced veterinary scientists.
Dr. Sarah Gildea, Senior R&D Scientist at Randox Teoranta in Dungloe, Co. Donegal, Ireland, has a BSc Equine Health, a PhD in Equine Influenza Virus, and spent many years working in the Virology Unit of The Irish Equine Centre prior to joining our team.
‘Randox Diagnostics: Leading the Field in Equine Health’
by Dr. Sarah Gildea BSc PhD, Senior R&D Scientist at Randox
“With over 30 years’ experience, Randox is a leading specialist in the development of veterinary diagnostic solutions. Our extensive product portfolio includes diagnostic reagents, quality controls, external quality assessment (RIQAS) and the Rx series of clinical chemistry analysers which are specifically designed to monitor the general health and well-being of a diverse range of animal species.
“Long established in the equine market, our clinical chemistry analysers provide the largest and most comprehensive test menu available and are used extensively to monitor the health and nutritional status of horses all around the world. In addition, our clinical chemistry tests can also be used for therapeutic drug monitoring, assessing reproductive fitness and as an indirect method in the diagnosis of certain equine diseases/conditions.
“Equine infectious anaemia (EIA) otherwise known as “swamp fever” is a viral disease affecting horses which can cause intermittent fever, anaemia, emaciation and eventual death. Although the disease is not always fatal, infected horses can become disease carriers thus posing a significant risk to other equines. Hence, rapid diagnosis is of fundamental importance. In a study carried out in Romania where the virus is endemic, a novel link between oxidative stress (measuring Total Antioxidant Status, Superoxide Dismutase and Glutathione Peroxidase) and EIA viral infection was established (Bolfă PF et al., 2012). The assessment of oxidative-antioxidative status in blood has also been investigated for a variety of other equine diseases and a correlation between oxidant-antioxidant imbalance and exercised induced pulmonary haemorrhage (Mills and Higgins, 1997), equine motor neuron disease (Delguste et al., 2007), recurrent airway obstruction (Deaton et al., 2006), joint disease (Dimock et al., 2000), endometritis and colic (Krumrych et al., 2013) has been identified. Such findings highlight the broader use of clinical chemistry tests in studying the pathogenesis and pathomechanisms of equine diseases.
“The increased participation of equine athletes in different sports and disciplines has resulted in a rise in the incidence of joint problems, with osteoarthritis now a common finding among performance horses. Similar to all athletes, the equine appendicular skeleton is under extreme pressure when participating in any intense physical training or equestrian events. Although some horses may remain clinically unremarkable, such physical exertion can result in various inflammatory disorders with subsequent increased risk of injury. Analysis of total protein in joint synovial fluid using the Randox Rx series of clinical chemistry analysers plays an important role in the study of equine orthopaedics worldwide and in the identification of appropriate therapeutic tools to enhance healing. The measurement of other well established biomarkers e.g. Total Antioxidant Status, Superoxide Dismutase, Serum Amyloid A and Creatine Kinase in monitoring response to exercise, transport, trauma and stress have all been previously reported using Randox technology and the results well documented in the scientific literature.
“In addition, using our clinical chemistry analysers, the measurement of seminal plasma antioxidant activity has been demonstrated as a useful indicator of semen quality and subsequent reproductive capability in performance stallions. In a study carried out by Härtlová et al., (2013) stallions experiencing induced sport workload stress were found to have higher levels of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) compared to those without workload stress. A correlation between an increased level of these intracellular enzymes in seminal plasma and defects in the spermatozoa membrane has previously been established (Katila, 2001).
“Randox is also actively involved in the development of tests for the detection of performance enhancing substances in horses. Such testing protects the safety and welfare of these animals and ensures that competitions are won primarily on merit. This testing is performed not only using our innovative Biochip Array Technology but also our Rx series of clinically chemistry analysers. During prolonged strenuous exercise, racehorses can experience acidemia. In an effort to enhance racing performance “bicarbonate loading” by trainers was first identified in the early 1990s and since then some racing authorities have identified a limit of total carbon dioxide (TC02) concentration which is permissible in horses prior to competition. A comparative study carried out in Australia which examined the capability of four clinical chemistry analysers (Beckman Synchron EL-ISE®, Beckman Synchron CX®5, Beckman UniCel DxC®600, Randox DaytonaTM) to measure TC02 in equine plasma reported that the Randox Daytona offered a high degree of accuracy and precision when compared to the gold standard. Of important logistical consideration however, this study identified the Randox Daytona as the only instrument sufficiently “portable” to allow TC02 testing to be carried out not only in a laboratory but also “onsite” at a racetrack in a laboratory vehicle (Jarrett et al., 2010).
“So as you can see – for all your equine needs from general health screening, monitoring response to exercise or injury, identifying suitable therapeutics and their appropriate threshold, studying the pathogenesis and pathomechanisms of certain equine diseases and assessing reproductive fitness – the Randox Rx series offers it all.”
For more information about our work in the area of Equine Health, please contact randoxpr@randox.com
References
Bolfă, PF., et al. (2012) Oxidant-antioxidant imbalance in horses infected with equine infectious anaemia virus . Vet J 2012, 192: 449-454
Deaton, CM., et al (2006) Comparison of the antioxidant status in tracheal and bronchoalveolar epithelial lining fluids in recurrent airway obstruction. Equine Vet J 2006, 38: 417-422
Delguste, C et al., (2007) Change in blood antioxidant status of horses moved from a stable following diagnosis of equine motor neuron disease . Can Vet J 2007, 48: 1165-1167
Dimock, AN., et al (2000) Evidence supporting an increased presence of reactive oxygen species in the diseased equine joint. Equine Vet J 2000, 32: 439-443
Härtlová, H., et al. (2013) Semen quality, lipid peroxidation, and seminal plasma antioxidant status in horses with different intensities of physical exercise. Acta Vet Brno 2013, 82: 031–035
Jarrett, M (2010): Alternative instrumentation for the analysis of total carbon dioxide (TC02) in equine plasma. Anal Bioanal Chem 2010, 397: 717-722
Katila, T (2001): In vitro evaluation of frozen-thawed stallion semen: A review. Acta Vet Scand 2001, 42: 199-217
Krumrych, W., et al. (2013) Oxidant/antioxidant status assessment of blood in selected equine diseases. Bull Vet Inst Pulawy 2013, 57: 225-230
Mills PC and Higgins AJ (1997) Oxidant injury, nitric oxide and pulmonary vascular function: implications for the exercising horse. Vet J 1997, 153: 125-148
