New findings show antimicrobial resistance on the rise
New findings show antimicrobial resistance on the rise
New antimicrobial resistance findings released by the European Centre for Disease Prevention and Control (ECDC) and the European Food Safety Authority (EFSA) have reported that antimicrobials used to treat diseases can be transmitted between animals and humans. The report presents data from 28 European Union (EU) Member States on humans, pigs, and calves under one year old.
Discussing the report, Poultry World documented that resistance to fluoroquinolones is now so high in Campylobacter bacteria that these antimicrobials no longer work for treatment of severe cases. Studies found that in Campylobacter, extremely high proportions of bacteria were resistant to ciprofloxacin and tetracyclines.
Despite the increase of antimicrobial resistance, Member States that have implemented stringent policies are noteworthy examples for other countries. Broiler farms in the United Kingdom (UK) reduced their antibiotic use by 82% between 2012 and 2017, producing half the meat eaten in the UK and using less than 9.7% of the total antibiotics licensed for food-producing animals.
In the UK, the poultry industry set up the Antibiotic Stewardship group in 2011 to tackle antimicrobial resistance and pre-empt the need for new laws. Coordinated by the British Poultry Council (BPC), participants worked together, shared industry data, and managed a 40% reduction of antibiotic use between 2016-2017. Fluoroquinolone use alone reduced by 91% in the UK. On-going work is to continue in order to improve antimicrobial use, with better data collection and advanced rapid testing methods for antimicrobial sensitivity.
Randox Food Diagnostics recognise the need for antimicrobial detection by providing reliable and economical testing methods to monitor multiple residues from a single sample with Biochip Array Technology. With the Antimicrobial II Array Plus, Randox Food Diagnostic’s offer the detection of 6 classes of antimicrobial compounds including quinolones and tetracycline from urine and tissue samples. Additionally, our tetracycline sensitive and quinolones ELISA kits rapidly uncover additional analytes, with excellent sensitivity levels.
For more information please contact us at info@randoxfooddiagnostics.com
Or visit the meat and seafood section of our website at www.randoxfood.com
NHS rolls out electronic prescription in the fight against antibiotic resistance
The NHS are rolling out electronic prescribing in the fight against antibiotic resistance.
A recent article in the Telegraph newspaper reports that;
“Health chiefs have drawn up the plans amid warnings that antibiotic resistance now poses as great a threat as climate change.”
Matt Hancock, the Secretary of State for Health and Social Care UK will be informing attendees of the World Economic Forum in Davos that “we are on the cusp of a world where a simple graze could be deadly”. He has stated that it needs to be treated as a “global health emergency” and wants to cut the use of drugs across the country by 15% by setting targets.
The head of the NHS Mr Simon Stevens, said that; “much of the change would be achieved by the rollout electronic prescribing across the health service.” This would allow health officials to detect areas that are prescribing the most antibiotics so that they can try and persuade medics to cut down.
Prime Minister Theresa May said: “The increase in antibiotic resistance is a threat we cannot afford to ignore.
“Government data shows that, since 2014, the UK has cut the amount of antibiotics it uses by more than 7 per cent and sales of antibiotics for use in food-producing animals has dropped by 40 per cent.”
The NHS antimicrobial resistance (AMR) report 2015 stated:
“The amount of antimicrobials used in food production internationally is at least the same as that in humans, and in some places is higher. For example, in the US more than 70% of antibiotics that are medically important for humans are used in animals.
“When properly used, antibiotics are essential for treating infections in animals, but excessive and inappropriate use of the drugs is a problem.
A considerable amount of antibiotics are used in healthy animals to prevent infection or speed up their growth. This is particularly the case in intensive farming, where animals are kept in confined conditions.”
In order to help the fight against AMR Randox Food Diagnostics are constantly researching and developing new ways to screen for antibiotics across wine, honey, meat, seafood, dairy, feed and cereals.
Randox Food Diagnostics have developed Biochip Array Technology a multiplexing platform which allows the screening of up to 54 food/feed samples for a large range of antibiotics in under 3 hours on the Randox Evidence Investigator analyser.
To find out more information on how Biochip Array Technology works visit our website at: www.randoxfood.com
Or contact us directly at: info@randoxfooddiagnostics.com
Study by Center for Disease Dynamics finds dramatic rise in global antibiotic consumption
A dramatic increase in global consumption of antibiotics has led public health experts to call for innovative new ways to rein in excessive use of the drugs, following a study by the Centre for Disease Dynamics, Economics and Policy, in Washington DC.
The study found a 65% rise in worldwide consumption of antibiotics from 2000 to 2015, despite efforts to encourage more prudent use of the drugs. The unrestrained use of antibiotics is the main cause of the increasing appearance of drug-resistant infections, which now kill more than half a million people worldwide. A report in 2014 predicted that the spread of drug resistance could claim millions of lives per year by 2050.
Eili Klein, an author of the study, which was published in Proceedings of the National Academy of Science, criticised the global response to the global antibiotic resistance crisis as “slow and inadequate” and called for a “radical thinking” of antibiotic consumption.
At Randox, our pioneering R&D teams have developed a revolutionary swab test for respiratory infections which will help to reduce the unnecessary prescription of antibiotics. Earlier this year, Public Health England reported that 59% of people who visited their GP with a sore throat were prescribed antibiotics, in spite of only 13% actually needing them.
The new Randox swab test indicates the cause of the infection and whether a patient needs antibiotics or not, by rapidly detecting and identifying the cause of 21 respiratory infections in just 5 hours
The test assists the clinician in prescribing the appropriate antibiotic.
John Lamont, Lead Scientist at Randox Laboratories, said;
“Current diagnostic testing for respiratory infections takes at least 36 hours to confirm the nature of an infection, and they cannot name and categorise infections as bacterial or viral in the way our new respiratory test can.”
This test, if widely adopted, could allow medical practitioners to make the correct treatment choice on the same day as examination and before patients have already begun a precautionary course of inefficient antibiotics. It would also have additional efficiency savings for the NHS, by eliminating the need for lengthy microbiology lab tests and unnecessarily prescribing drugs which are not needed.
This new rapid and accurate test will give clinicians confidence in their diagnosis of respiratory infections and will allow for quicker treatment if necessary, which benefits patient outcomes. By reducing the prescription of unnecessary antibiotics, we can limit their use only for when they are truly needed.
The test is also available as a Randox Health Cough, Cold & Flu offering, and can be carried out by booking an appointment with Randox Health at our clinics in Crumlin, Holywood or London, or by arranging the mobile clinic to visit you at your home or place of work.
Book an appointment with one of our clinics, or arrange the mobile clinic, by phoning 0800 2545 130 or by clicking here.
For further information about the Randox Respiratory Infection Array please contact the Randox PR team by email: randoxpr@randox.com or phone 028 9442 2413
GPs are told to stop prescribing antibiotics for sore throats
Today, the National Institute for Health and Care Excellence has published guidelines that state doctors should not prescribe precious antibiotics for most people with sore throats and should instead recommend drugs like paracetamol.
The guidelines from NICE and Public Health England, which aim to limit the use of antibiotics, said doctors should only be prescribing the medicines for more severe cases that are most likely to have been caused by a bacterial infection.
This is despite recent research that suggests antibiotics are prescribed in 60% of sore throat cases, for which doctors are unable to tell if the infection is viral or bacterial.
The National Institute for Health and Care Excellence said most sore throats were caused by viral infections, which cannot be treated by antibiotics.
At Randox, our pioneering R&D teams have developed a revolutionary swab test for respiratory infections which indicates the cause of the infection and whether a patient needs antibiotics or not. This helps to limit the number of patients who are prescribed antibiotics unnecessarily.
The Randox test, which can rapidly detect and identify the cause of 21 respiratory infections in just 5 hours, assists the clinician in prescribing the appropriate antibiotic.
John Lamont, Lead Scientist at Randox Laboratories, said;
“Current diagnostic testing for respiratory infections takes at least 36 hours to confirm the nature of an infection, and they cannot name and categorise infections as bacterial or viral in the way our new respiratory test can.”
This test, if widely adopted, could allow medical practitioners to make the correct treatment choice on the same day as examination and before patients have already begun a precautionary course of inefficient antibiotics. It would also have additional efficiency savings for the NHS, by eliminating the need for lengthy microbiology lab tests and unnecessarily prescribing drugs which are not needed.
This new rapid and accurate test will give clinicians confidence in their diagnosis of respiratory infections and will allow for quicker treatment if necessary, which benefits patient outcomes.
The test is also available as a Randox Health Cough, Cold & Flu offering, and can be carried out by booking an appointment with Randox Health at our clinics in Crumlin, Holywood or London, or by arranging the mobile clinic to visit you at your home or place of work.
Find out more about the Cough, Cold & Flu Respiratory test here.
Book an appointment with one of our clinics, or arrange the mobile clinic, by phoning 0800 2545 130 or by clicking here.
For further information please contact the Randox PR team by email: randoxpr@randox.com or phone 028 9442 2413
Randox showcases most advanced dairy screening test on market at World Dairy Summit
Improving global dairy standards is the focus for Randox Food Diagnostics, which is demonstrating its latest advancement – the ‘InfiniPlex for Milk’ – at the 2017 World Dairy Summit. Over 1000 international delegates are expected to attend the event being held in Belfast’s Waterfront Hall between 30th October to 3rd November.
With maintaining consumer confidence in the safety and integrity of dairy products featuring as one of the key topics at this year’s summit, the Northern Ireland-based company is keen to showcase how it can help producers get an edge in the market through ensuring food safety.
At the International Dairy Foundation’s annual conference event Randox Food will be showcasing the InfiniPlex, an innovative system which tests for 130 restricted drugs from one sample, such as antibiotics, non-steroidial anti-inflammatory and anti-parasitic drug residues. This is the most comprehensive array on the market and achieves 98% compliance with EU regulations.
The Infiniplex also identifies a number of drug compounds which are not on the EU’s regulated list but which are unsuitable for human consumption. Using this multiplex system ensures that any Randox-tested dairy product will be the safest on the shelf.
Dr FitzGerald, Founder and Managing Director of Randox Laboratories, commented;
“It is our aim to ensure that dairy producers have access to the latest and most comprehensive milk safety screening technologies. The Infiniplex for Milk is the world’s first screening technology that ensures dairy processors are compliant with regulations. By meeting its complex needs, InfiniPlex is changing the face of the global dairy industry.”
David Ferguson, Global Business Manager for Randox Food Diagnostics, added;
“Standard industry practice means the primary residues for which screening is carried out is usually limited to two certain varieties of antibiotics. The InfiniPlex for Milk provides a unique insight into the specific combination of drug compounds detected in a single sample offering drug discrimination that allows the user to see what commercially available drug was administered at animal level. Using our multiplex testing offers the global milk industry the most comprehensive product for the analysis of veterinary drug residues in food, protecting the food industry and the consumer.”
The International Dairy Federation World Dairy Summit takes place in the Waterfront Hall. Randox Food Diagnostics can be found at Booth 5.
For further information about Randox Food Diagnostics milk testing, please visit: http://www.randoxfood.com/Matrices/Milk
For any further questions please contact Randox PR by phoning 028 9445 1016 or emailing RandoxPR@randox.com
Randox responds to antibiotic resistance warning from NI Chief Medical Officer Dr. Michael McBride
Today, Northern Ireland’s Chief Medical Officer Dr. Michael McBride has stated that antibiotic resistance is now the greatest risk to human health and medicines worldwide. Dr. McBride said; “Currently 700,000 people die worldwide each year from drug resistant infections and this figure is forecasted to reach 10 million deaths by 2050, if the problem is ignored.”
It is rather alarming therefore that 70% of GPs admit that they prescribe antibiotics when they are unsure if they are treating a viral or bacterial infection. By prescribing antibiotics for viral infections, which can’t be combatted with antibiotics, patients are being exposed to antibiotics which are of no benefit.
John Lamont, Lead Scientist at Randox Laboratories, said that “Current diagnostic testing for respiratory infections takes at least 36 hours to confirm the nature of an infection, and they cannot name and categorise infections as bacterial or viral is the way our new respiratory test can.”
At Randox, our pioneering R&D teams have developed a revolutionary swab test for respiratory infections which indicates the cause of the infection and whether a patient needs antibiotics or not. This helps to limit the amount of patients who are prescribed antibiotics, reducing antibiotic resistance.
The Randox test, which can rapidly detect and identify the cause of 21 respiratory infections in just 5 hours, can also subsequently determine the appropriate antibiotic drug treatment for patients.
This test, if adopted by GP surgeries, could allow medical practitioners to make the correct treatment choice on the same day as examination and before patients have already begun a precautionary course of inefficient antibiotics. It would also have additional efficiency savings for the NHS, by eliminating the need for lengthy microbiology lab tests and unnecessarily prescribing drugs which are not needed. This new rapid and accurate test will give the GP confidence in their diagnosis of respiratory infections and will allow for quicker treatment if necessary, which benefits patient outcomes.
The test is also available as a Randox Health Cough, Cold & Flu offering, and can be carried out by booking an appointment with Randox Health at our clinics in Crumlin, Holywood or London, or by arranging the mobile clinic to visit you at your home or place of work.
So what action can we take to limit the looming antibiotic resistance crisis?
- Ask your GP if tests will be performed to make sure you even need antibiotics and that the correct antibiotic is prescribed.
- Take the antibiotics as prescribed. Make sure you complete the prescribed course, even when you start feeling better. This makes sure that all bacteria from your current infection are eradicated, leaving none behind that could potentially develop resistance to your antibiotic.
- Only take antibiotics prescribed for you; do not share or use leftover antibiotics. Taking the wrong medication will delay correct treatment and allow bacteria to multiply, and potentially develop a resistance to the antibiotic you are using incorrectly.
Find out more about the Cough, Cold & Flu Respiratory test here.
Book an appointment with one of our clinics, or arrange the mobile clinic, by phoning 0800 2545 130 or by clicking here.
For further information please contact the Randox PR team by email: randoxpr@randox.com or phone 028 9442 2413
Randox Food Diagnostics harnessing science of antibiotic screening to ensure safer honey
Global leader in food screening technology, Randox Food Diagnostics have developed a range of pioneering honey quality tests which are being adopted by apiculturists across the world to ensure the safety and quality of their produce.
The array of tests, developed by the Antrim-based firm, are being showcased this week at the world’s largest apiculture meeting, the Apimondia International Conference, being held in Istanbul, Turkey from September 29th to October 4th.
The company hopes to highlight to consumers and producers about the importance of food safety, and in particular the dangers of antibacterial residue in food. Scientists have warned that antibiotics used in food production, are passing through the food chain to consumers and therefore contributing to the rise in infections caused by antibiotic-resistant bacteria.
Randox Founder and Managing Director, Dr Peter FitzGerald, commented;
“As a company committed to supporting the fight against antibiotic resistance we must continue to drive awareness amongst producers and consumers alike.
“We are working closely with industry to promote a responsible approach to antibiotic use in food production and we hope that by working with some of the biggest names in the apiculture market, other honey producers will see the benefits of being able to offer their customers complete consumer confidence in a high quality, and importantly, safe product.”
At Apimondia 2017 Randox Food Diagnostics will showcase a range of major technological advancements including the firm’s Antimicrobial Array 1 Ultra, Antimicrobial Array II Plus and Antimicrobial Array V. Thanks to Randox’s patented Biochip Array Technology, these testing panels can simultaneously screen for multiple antibiotics that are sprayed on beehives to ensure the safety of the colony, from only one sample of the produce.
Randox Food’s Antimicrobial Arrays join the company’s already extensive menu of honey screening tests, including its test for Hydroxymethylfurfural (HMF), a test for an organic compound produced by dehydration of sugars, which can be indicative of overheating, poor storage conditions or aged honey. The test was recently validated by leading South American honey producer Geomiel, which credited Randox Food for delivering an immediate improvement in the quality of its honey products.
David Ferguson, Global Business Manager for Randox Food Diagnostics, commented;
“We welcome the fact that so many of the world’s leading producers, including Geomiel, have embraced our vision of continuously improving testing standards.
“We have invested a lot in simplifying the process of conducting multiple tests, and consolidating this onto one unique biochip is a cost-effective way for the honey industry to maintain and improve standards. Apimondia 2017 attendees will be offered a complete testing bundle – including our popular analysers, the Randox Evidence Investigator and RX misano, to enable them to test for antibiotics and assess quality in one easy-to-manage system.
“Another unique feature of what we offer here at Randox Food Diagnostics is our ever-expanding test menu. The RX misano for example has a customisable test menu which allows clients to upload new parameters using USB, ensuring access to the most up-to-date tests on the market.
“We will be inviting Apimondia guests to learn more about the upcoming launch of our new pesticide tests, which will provide multiple results for the world’s most prevalent pesticides, such as Amitraz, Acetamiprid, Carbofuran, Carbaryl, and Paraquar. We remain committed to supporting food producers by providing them with the newest and highest quality tests.”
For further information about Randox Food Diagnostics honey testing, please visit: http://www.randoxfood.com/Matrices/Honey
For any further questions please contact Randox PR by phoning 028 9445 1016 or emailing RandoxPR@randox.com
Randox Food Diagnostics test committed to fighting antibiotic resistance is awarded AOAC Performance Tested Certification
After several years of dedicated R&D, Randox Food Diagnostics are pleased to announce that the industry’s leading body, the AOAC, has granted its Performance TestedSM certification to the company’s Antimicrobial Array I Ultra Kit (License Number 051705).
AOAC standards are used globally to facilitate public health and safety and promote trade, and the rigorous three year certification process was completed in conjunction with the US Food and Drug Administration Center for Veterinary Medicine validation protocol. In addition to internal validation studies and reporting to the AOAC Research Institute, an external independent expert laboratory was required to evaluate the methodology.
Achieving the AOAC Performance TestedSM certification sends a strong statement to the industry about RFD’s commitment to support food producers by providing the highest quality diagnostic tests.
The widespread use of antibacterial agents in veterinary practice, as bacteriostatic agents as well as to promote growth, has increased the concern about the levels of contamination of food products that can be consumed by the public. To protect both the consumer and the industry, regulatory authorities have specified maximum residue limits.
The Antimicrobial Array I Ultra Kit tests for 13 antibacterial agents: for consumer protection, the presence of these compounds in the food supply is highly regulated or banned. This Biochip based kit uses a multi-analytical approach, and therefore maximises detection capability which will improve food safety.
Head of Randox Food Diagnostics, David Ferguson, said:
“This is a major achievement for our team and we are delighted to receive this certification from AOAC. One of our central goals is to be a catalyst for improving food safety, which is why we invested so much into tackling the widely-reported dangers of antibacterial residue in food.
“There’s a growing awareness among consumers and producers about the critical issue of food safety. The Antimicrobial Array I Ultra Kit will meet the increasing demand for highly accurate diagnostic tests.”
The test kit is exclusively available on Randox’s proprietary Biochip Array Technology.
For more information please contact enquiries@randoxfood.com
About AOAC-RI
The AOAC Research Institute (AOAC-RI) was incorporated in 1991 as a wholly owned subsidiary of AOAC INTERNATIONAL. The AOAC-RI serves as an independent, third-party, nongovernment administrator of AOAC conformity assessment programs including the AOAC Performance Tested MethodsSM (PTM) and Official Methods of AnalysisSM (OMA) programs for alternative and sole source methods.
For more information, visit www.aoac.org.
Children at increased risk of drug-resistant infections after taking antibiotics
Children who are prescribed antibiotics are 12 times more at risk of acquiring drug-resistant infections in the weeks afterwards, according to a leading public health figure.
Public Health England medical director Paul Cosford told the Science and Technology Committee this week that the risk is greater for younger people than it is for adults.
“We’ve got good evidence that if you or I have a course of antibiotics now, within three months our risk is three times to get a resistant infection of some sort because we’ve had the antibiotics affecting all the organisms in our bodies. If you’re a child you’re 12 times more likely to get a resistant infection in the three months after a course of antibiotics.”
Whilst acknowledging that the drugs do a have part to play, Cosford stressed this had to be done correctly – and compared antibiotics to “using a pesticide in a rich woodland.” At the same time as tackling the harmful infection the drugs will destroy useful bacteria in the gut.
The information was taken from two major reviews on the routine-use of antibiotics in primary care, and he said the results underline the importance of continued efforts to decrease prescription rates.
“There is a growing body of evidence that taking antibiotics makes it more likely that your next infection will be a resistant one, so prudent use of these life-saving medicines is essential.”
One review looked at children who had urinary tract infections and found that they were more than 13 times more likely to have contracted drug-resistant strains if they had been given antibiotics in the previous six months.
The 2014 Longitude Prize survey of antibiotics in primary care revealed that 90% of British GPs felt pressure from patients to give out the drugs, and almost half had done so knowing it would not treat the patient’s condition.
Mark Woolhouse, Professor of Infectious Disease Epidemiology at Edinburgh University told The Guardian that the consequences of antibiotic resistance required a global plan, just as with climate change. However he added that, “In terms of the threat to my own health, and that of my children, and my family’s health, I am much more concerned about antimicrobial resistance than I am about climate change.”
Randox is supporting the battle against antibiotic resistance. Our wide range of related products includes our Respiratory Multiplex Array which tests 22 common virus and bacteria pathogens can detect whether an antibiotic should be prescribed.
John Lamont, Chief Scientist at Randox Laboratories, whose team developed the molecular test, commented;
“Current diagnostic testing for respiratory infections takes at least 36 hours to confirm the nature of an infection, and they cannot name and categorise infections as bacterial or viral in the way that our respiratory test can. C-reactive protein tests, for example, that are currently in use can only indicate whether a bacterial infection is likely. We need more than just guess work to combat the antibiotic resistance pandemic.”
For more information, please visit http://www.randox.com/respiratory-multiplex-array/ or contact RandoxPR@randoxcom
Randox calls for patients and prescribers to āresist and desistā antibiotic use
- UK-based diagnostics firm supporting call for responsible use of antibiotics in conjunction with European and International Antibiotics Awareness initiatives
- New molecular diagnostic multiplex assays hold the key to first-time, accurate diagnosis of infectious diseases
- Assays have the power to diagnose primary, secondary and asymptomatic co-infections to inform appropriate antibiotic prescribing
UK-based diagnostics company, Randox Laboratories, is supporting the call for patients and prescribers to ‘resist and desist’ antibiotic use in the fight against antimicrobial resistance this European Antibiotics Awareness Day. Coinciding with international awareness weeks in Australia, Canada and the USA, the concerted efforts of health authorities around the world to curb the spread of antimicrobial resistance is testimony to the global reach of the issue.
Now declared a ‘major threat’ by the World Health Organisation, Randox has been working at the forefront of this global challenge to deliver effective diagnostic solutions to arm against this growing problem. Developed over two decades of research and an investment of £200m, Randox’s innovative Biochip Array Technology (BAT) is the latest weapon in the fight against antimicrobial resistance, with the ability to simultaneously detect multiple pathogens in a single test for rapid and accurate diagnosis.
Randox’s range of molecular assays within infectious disease enable the detection of primary, secondary and asymptomatic co-infections for a more comprehensive understanding of the drivers of infection in individual patients. The Randox STI Multiplex Array simultaneously detects up to 10 pathogens from a single patient sample, whilst the Randox Respiratory Multiplex Array rapidly screens for 22 bacterial and viral upper and lower respiratory tract infections, with same day result reporting, for rapid diagnosis.
As Randox Managing Director Dr Peter FitzGerald CBE FREng explains, screening for all potential pathogens in infectious disease is vital in ensuring accurate diagnoses can be made; “Even after a confirmed diagnosis, many patients who haven’t been tested for a wider range of pathogens may harbour co-infections, impeding the effectiveness of therapeutic treatment and prolonging exposure to infection.
“Through a more comprehensive screening strategy at initial presentation, a complete patient profile can be obtained which will give clinicians greater understanding of the working of the disease and allow them to diagnose and prescribe correctly, ruling in or out the need for antibiotics, and helping to control their appropriate use.”
Antibiotic resistance has largely been fuelled by patient and prescriber overreliance on using antibiotics to treat disease. Once considered to be ‘magic bullets’ for curing infections, antibiotics are now firing blanks as they become ineffective against many common and treatable infectious diseases, such as the sexually transmitted infection, Neisseria gonorrhoeae, and respiratory tract infections such as staphylococcus aureus and streptococcus pneumoniae, which have been shown to be acquiring increasing levels of resistance to antibiotic treatment.
“First-time, accurate diagnosis of infection through molecular testing is key to treating infections correctly. The availability of these assays provides a powerful weapon in the fight against antimicrobial resistance and we would encourage health providers around the world to utilise this technology to help curb the spread of the problem.”
For more information visit Randox: www.randox.com.
