World-first milk test for cattle herd health developed by Randox scientists
World-first milk test for cattle herd health developed by Randox scientists
04 March 2020
World-first milk test for cattle herd health developed by Randox scientists
Randox scientists have today revealed a revolutionary new method for Bovine disease testing which will radicalise cattle screening against some of the world’s most prevalent bovine viruses, bacteria and parasites.
Named the Bovine Pathogen Array, the test is designed to facilitate prompt diagnosis and the identification of co-infection, which aids in the reduction of the spread of disease, limits the need for medical intervention and milk withdrawal periods, and also ensures maximum efficiency at the producer level.
The veterinary multiplex IVD immunoassay from global diagnostics company Randox, headquartered in Northern Ireland, is the first of its kind on the market – detecting antibodies against six pathogens simultaneously from a single milk sample, rather than the standard more time-consuming method of singleplex ELISA testing currently required for each individual disease.
David Ferguson, Managing Director, Randox Food Diagnostics, commented;
“Our Bovine Pathogen Array is the first of its kind in the world and has the potential to revolutionise how cattle are diagnosed and how quickly pathogens are spread amongst a herd. Simultaneous detection of the rifest, and most problematic, bovine viruses, bacteria and parasites has not been attempted before, and currently, six to seven separate ELISA tests must be conducted in order to obtain the same results as those delivered by the Bovine Pathogen Array.
“Bringing this product to market has been a priority at Randox Food Diagnostics and we are sure that arming industry professionals with quicker and more accurate diagnostic tools will lead to increased yields, increased profit margins for producers and, ultimately, better bovine health.”
The new Bovine Pathogen test, which is conducted on a unique piece of testing technology called the Biochip, generates results in approximately 2.5 hours, allowing faster diagnosis and identification of infected cattle. Milk samples are collected from the herd, added to a Biochip, and then placed in the corresponding analyser (called the Evidence Investigator) which runs tests for multiple diseases – Bovine Viral Diarrhoea (BVD), Infectious Bovine Rhinotracheitis (IBR), Paratuberculosis (Johne’s Disease), Leptospirosis, Neospora Caninum and Fasciola Hepatica (Liver Fluke) – all at once.
Highly contagious and, in many cases, untreatable, there has been much concern regarding outbreaks of these dangerous pathogens in the past number of years. With a global economic impact, high mortality rates, increased premature culling, decreased reproductive performance and reduced milk yield as direct losses, vital research has been long awaited in order to tackle these dangerous conditions faster and more effectively.
David continued;
“The Randox Bovine Pathogen Array contains a range of well-established antigens complemented by additional select novel analytes for BVD and Neospora Caninum. It can also differentiate between IBR vaccinated and naturally infected animals (DIVA capacity) when used in conjunction with selected vaccines. This comprehensive test menu will significantly contribute to advances in disease research and add to scientific knowledge already available with regards to coinfection, surveillance, vaccine performance and risk factors associated with disease outbreaks.
“We are proud to be able to provide reassurance for dairy producers, enabling them to get to the root of the issue before contamination occurs across the herd.”
The new Bovine Pathogen Array was recognised as most innovative assay at the recent IDF World Dairy Summit, receiving 1st prize in the poster competition. It is now available from Randox Food Diagnostics.
Please email enquiries@randoxfooddiagnostics.com for further information.
Want to know more?
Contact us or visit our Randox Food Diagnostics website.
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The use of antibiotics in the dairy industry
27 February 2020
The use of antibiotics in the dairy industry
The use of antibiotics in the dairy industry
In this month’s Randox Food Diagnostics blog, we look at the dairy industry and their use of antibiotics.
Antibiotics are used in the dairy industry routinely for pure preventative purposes. Due to poor conditions and hygiene, it is common that cattle will become infected which results in loss of milk yield and beef. Antibiotics are used to alleviate and prevent further suffering from potential zoonotic diseases.
Antibiotics are administered to cattle through a blanket use practice, within a herd to ensure all are treated. Once administered to the animal they must be given a ‘dry’ period when the dairy cattle are allowed to rest between lactations. This lasts roughly around 60 days in which a herd cannot be milked to ensure the antibiotics are out of the cattle’s milk. This however is at a cost to the farmer and cattle cannot be rushed back into milking too soon after administration.
To support the global dairy industry, and to help dairy processors monitor their use of antibiotics, Randox Food have developed the most comprehensive testing methods for milk.
The InfiniPlex for Milk Array is the world’s first screening technology that allows users to test for 130+ contaminants in milk in under 22 minutes. In addition to testing for antibiotics, InfiniPlex can detect anti-parasitic, non-steroidal, anti-inflammatory and anti-parasitic drug residues from a single sample using patented Biochip Array Technology.
Available on both the Evidence Investigator, a semi-automated system, capable of analysing up to 48 samples in under 2 hours and the Evidence MultiSTAT, a fully automated system that delivers results from a single neat sample of milk in under 22 minutes.
If you are a centralised laboratory, internal surveillance programme, low throughput laboratory or a dairy processor we have the perfect solution for your testing needs.
For more information on the antibiotic screening arrays available, contact info@randoxfooddiagnostics.com to find out how Randox Food can simplify your screening practices today.
Want to know more?
Contact us or visit our Randox Food Diagnostics website.
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Milk
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Over 100 Dairy Cows put down following Ergotism Outbreak in New Zealand
This week over 100 cows on a farm in New Zealand had to be put down after digesting fungus from an infected feed supply. The herd in the Southland and Otago regions was suffering from ergot toxicity. Randox Food Diagnostics have developed the only test for this fungus on the market, which can protect your animals from injury or death.
Ergot Alkaloids are a naturally occurring fungus most commonly found in grains and grasses. Produced by a group of fungi called the Claviceps species, they infect seed heads of plants during the flowering period. The fungus replaces the developing grain with toxic ergot. The dry summer and wet autumn this year provided the optimum growing conditions for the fungus.
Typically, it causes lameness and swelling of the fetlocks and hock joints but in the most severe cases animals can lose tips of their tails, or ears or even their hooves. As in this case, it can result in animals being put down.
While all animals are at risk of contracting ergot, it is most commonly found in cattle.
According to the report, VetSouth Winton veterinarian Hayden Dore confirmed four cases have been reported in Southland and South Otago with a large number of infected cows.
“Over time it effectively causes one or more of the limbs to become gangrenous. Signs of ergot toxicity generally start with a disinterest in feed, before moving to lameness in the limbs, which presented similarly to foot rot, but without the separation of the toes. Once the limbs go cold from lack of blood supply, it would take about a week before the limbs began to fall off,” he said.
“One herd with 900 milking cows had around 130 cows infected by the poisonous fungus, with subsequently 61 of them being put down.”
Testing for Ergot Alkaloids
Randox Food Diagnostics offer the only array on the market to test for Ergot Alkaloids. Validated for flour and seed, the ELISA test offers excellent limits of detection for the toxin Ergotamine at 1ppb.
Click here for more information on the Ergot Alkaloid ELISA kit or email info@randoxfooddiagnostics.com and your area’s Business Development Executive will contact you.