Drug Abuse Screening in the Emergency Department
Drug Abuse Screening in the Emergency Department
21 October 2019
Drug Abuse Screening in the Emergency Department
On a global scale, emergency departments have been providing critical access to the health care system for many years, however, more recently visits to the emergency department has been an opportunity to identify patients with substance use disorders. Screening patients for illicit drugs and drug abuse has become increasingly more regular when a patient is admitted to the emergency department. Screening is vital to treat a patient with effective treatment. Nearly half of all emergency department visits in the US are categorized as relating to substance use disorders.
In a study completed at Ghent University Hospital in 2017 it was found that the most frequently reported drugs abused by emergency department patients are cannabis, cocaine, amphetamines, and opiates. It is important to screen patients in the emergency department if the patient is showing signs of confusion, deliriousness, unconsciousness, panic attacks, chest pain, difficulty breathing, vomiting, or seizures as these symptoms usually indicate drug intoxication or overdose.
Randox Toxicology’s Evidence MultiSTAT is a fully automated immunoanalyser that enables on-site simultaneous detection of up to 21 analytes from a single sample, making it ideal for an emergency department. It requires a small sample volume and generates results in 20 minutes. The process from sample entry to results can be completed in 3 simple steps, with minimum room for human error. The MultiSTAT is designed to analyse as quick, simple and reliable as possible.
| Available Tests | ||
| AB-CHMINACA | AB-PINACA | Amphetamine |
| Barbiturates | Benzodiazepines I (Oxazepam) | Benzodiazepines II (Lorazepam) |
| Benzoylecgonine (Cocaine Metabolite) | Buprenorphine | Cannabinoids (THC) |
| Creatinine | Ethyl Glucuronide (EtG) | Fentanyl |
| LSD | Methadone | Methamphetamine |
| Opiate | Oxycodone | Phencyclidine (PCP) |
| Pregabalin | Propoxyphene | Tramadol |
| Tricyclic Antidepressants (TCA) | UR-144/XLR-11 | α-PVP (Flakka) |
If you would like to find out more about the Evidence MultiSTAT, Biochip Array Technology, or our Evidence range of analysers, contact info@randoxtoxicology.com or visit www.randoxtoxicology.com
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Drugs of Abuse – A Global Pandemic
4th September 2019
Drugs of Abuse – A Global Pandemic
The prevalence of drug addiction and abuse across the globe has become a growing concern. It is currently estimated that 71 million people use drugs of abuse with around 166,000 direct deaths occurring from drug use in 2017.
The WHO (World Health Organisation) estimate that 11 million people inject drugs across the globe, of which 1.3 million are living with HIV, 5.5 million with hepatitis C, and 1 million with both HIV and hepatitis C. In addition to infectious disease, long term drug abuse increases the risk of several cancers, cardiovascular effects, respiratory effects, gastrointestinal effects, kidney & liver damage and mental health issues.
The abuse of drugs is one of the most pressing issues in the USA and other countries globally. Drug abuse not only affects the individual, but can also have far-reaching consequences that affect family, employment, personal health, health care systems, local communities, and society as a whole.
Global Drug Abuse – The buzz that keeps on going!
> Misuse of illicit drugs affects society through secondary costs incurred such as crime, reduced productivity at work, and health care expenses.
> Substance abuse costs the US health care system about $11 billion, with overall costs reaching $193 billion.
> Substance abuse and addiction also affects other areas of life leading to broken families, destroyed careers, death due to negligence or accident, domestic violence, physical abuse and child abuse.
> Drug abuse and addiction changes the chemistry of your brain. The longer an individual abuses drugs, the more damage is caused, making it more difficult to return to ‘normal’ during drug rehabilitation.
> Treating and tackling drug addiction is a challenge. As drug treatment and health services continue to fall short, there is an increased need to continuously adapt drug detection and analysis.
Randox laboratories are at the forefront, aiding the fight against drugs of abuse with a comprehensive range of 10 drugs of abuse assays including several stimulants, sedatives and opioids available to run on Randox’s very own clinical chemistry analysers, the RX series. To find out now how Randox is helping to tackle the ongoing prevalence of drugs of abuse click here or buy directly from the Randox Online Store.
About Randox Laboratories
As a world leader in the in-vitro diagnostic industry with over 35 years’ experience, Randox is leading the charge in moving from a one-size-fits-all approach towards decisions, practices and products tailored to the needs of the individual. This innovative approach to diagnostics has facilitated the development of revolutionary products designed specifically to enhance a patients’ quality of life.
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Contact us or visit our Drugs of Abuse pages to learn more.
Related Products
RX Overview
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Therapeutic Drugs Monitoring
References
The world’s most extensive Drugs of Abuse Test Menu
Randox Toxicology offers the most comprehensive Drugs of Abuse (DoA) test menu across multiple forensic matrices. Our level of expertise in toxicology research and development allows us to adapt quickly to the ever-changing market influences and develop assays for current and novel drugs trends. Excellent assay precision and performance eliminates false reporting, therefore reducing unnecessary confirmatory tests and time lost in the laboratory as a result. Our Biochip Arrays offer CVs typically less than 10%, producing an accurate drug profile to ensure confidence in results.
| DoA II | ||
| Buprenorphine | Ketamine | Oxycodone I |
| Creatinine | LSD | Oxycodone II |
| Fentanyl | MDMA | Propoxyphene |
| Generic Opioids | Methaqualone | – |
The Evidence Series of immunoassay analysers are powered by Biochip Array Technology and combine the latest technological advances for drug residue detection using immunoassay principles. The Drugs of Abuse II panel is available for both the Evidence and the Evidence Investigator analysers. The Evidence has a throughput of 90 samples per hour, testing up to 44 tests per sample. The Evidence is a fully automated batch immunoanalyser, allowing for 3960 tests per hour, while the Evidence Investigator is a semi-automated, bench top analyser with testing capabilities of 2376 tests in 70 minutes.
To find out more about our Biochip Array Technology and our Evidence Series analysers, visit www.randoxtoxicology.com, or email us at info@randoxtoxicology.com
Toxicology Control Calibrators
Analytes
- Oxazepam
Drugs of Abuse Array I Plus Calibrator
Multi-analyte calibrator designed for use with the Drugs of Abuse Array I Plus.
Features & Benefits
- Lyophilised for enhanced stability
- Stable to expiry date at 2oC – 8oC
- Urine- Reconstituted stability of 14 days at 2oC – 8oC
- Whole Blood – Reconstituted stability of 7 days at 2oC – 8oC or 14 days at -20oC
| Description | Size | Analytes | Cat No | |
|---|---|---|---|---|
| Drugs of Abuse Assay I Plus (Urine) Calibrators | 9 x 1ml | 14 | EV3744 | |
Analytes
- Amphetamine
- Barbiturates
- Benzodiazepine 1
- Benzodiazepine 2
- Buprenorphine
- Cannabinoids
- Cocaine Metabolite
- MDMA
- Methadone
- Methamphetamine
- Opiates
- Phencyclidine
- Tricyclic Antidepressants
- Creatinine
Drugs of Abuse Array II Calibrators
Dedicated calibrator designed for use the Drugs of Abuse Array II control.
Features & Benefits
- Lyophilised for enhanced stability
- Stable to expiry at 2oC – 8oC
- Urine- Reconstituted stability of 7 days at 2oC – 8oC or 28 days at -20oC
- Whole Blood – Reconstituted stability of 7 days at 2oC – 8oC or 28 days at -20oC
| Description | Size | Analytes | Cat No | |
|---|---|---|---|---|
| Drugs of Abuse Array II (Whole Blood) Calibrator Series | 9 x 1ml | 11 | EV3687 | |
Analytes
- 3,4 Methylenedioxymethamphetamine (MDMA)
- Ketamine
- Lysergic Acid Diethylamide (LSD)
- Methaqualone
- Buprenorphine
- Fentanyl
- Generic Opioids
- Oxycodone I
- Oxycodone II
- Propoxyphene
- Creatinine
Drugs of Abuse Array III Calibrators
Multi-analyte calibrator designed for use with the Drugs of Abuse Array III control.
Features & Benefits
- Lyophilised for enhanced stability/li>
- Stable to expiry date at 2°C – 8°C
- Reconstituted stability of 7 days at 2°C – 8°C
| Description | Size | Analytes | Cat No | |
|---|---|---|---|---|
| Drugs of Abuse Array III (Urine) Calibrator Series | 9 x 1ml | 11 | EV3829 | |
| Drugs of Abuse Array III (Whole Blood) Calibrator Series | 9 x 1ml | 11 | EV3797 | |
Analytes
- Chloral Hydrate Metabolite
- Ethyl Glucuronide
- Fentanyl
- Ketamine Metabolite
- Meperidine
- Meprobamate
- Zaleplon
- Zolpidem
- Zopiclone
- 7-amino Flunitrazepam
- Creatinine
Drugs of Abuse Array IV Calibrator
Multi-analyte calibrator designed for use with the Drugs of Abuse Array IV control.
Features & Benefits
- Lyophilised for enhanced stability
- Stable to expiry date at 2°C – 8°C
- Reconstituted stability of 7 days at 2°C – 8°C
| Description | Size | Analytes | Cat No | |
|---|---|---|---|---|
| Drugs of Abuse Array IV (Whole Blood) Calibrator | 9 x 1ml | 14 | EV3808 | |
Analytes
- Acetaminophen
- Dextromethorphan
- Escitalopram
- Fluoxetine
- Haloperidol
- Ibuprofen
- Methylphenidate
- Salicylate
- Salicyluric Acid
- Sertraline
- Tramadol
- Trazodone
- Tricyclic Antidepressants
- Creatinine
Drugs of Abuse Array V Calibrators
Multi-analyte calibrator designed for use with the Drugs of Abuse Array V control.
Features & Benefits
- Lyophilised for enhanced stability
- Stable to expiry date at 2°C – 8°C
- Reconstituted stability of 7 days at 2°C – 8°C
| Description | Size | Analytes | Cat No | |
|---|---|---|---|---|
| Drugs of Abuse Array V (Urine) Calibrator Series | 9 x 1ml | 10 | EV3815 | |
| Drugs of Abuse Array V (Whole Blood) Calibrator Series | 9 x 1ml | 10 | EV3847 | |
Analytes
- Bath Salts 1 (Methcathinone and Mephedrone)
- Bath Salts 2 (MDPV)
- Benzylpiperazines
- Mescaline
- Phenylpiperazines
- Salvinorin
- Synthetic Cannabinoids 1
- Synthetic Cannabinoids 2
- Synthetic Cannabinoids 3
- Synthetic Cannabinoids 4