How Randox R&D Scientists are helping to change healthcare: An introduction to diagnostics for BSW 2017

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How Randox R&D Scientists are helping to change healthcare: An introduction to diagnostics for BSW 2017

In celebration of British Science Week 2017, we will be giving you an introduction to diagnostics, and exploring how Randox Scientists are helping to change healthcare.

 

You may or may not already know that Randox are one of the leading diagnostics companies globally.  But what exactly does clinical diagnostics involve?  It is one of the fundamental steps of finding out what is wrong with a person when they are ill.  Read on to find out a bit more about diagnostics, and how the Randox Reagents R&D Scientists are helping to change healthcare globally!

What is a diagnostic test?

A diagnostic test is any kind of analysis performed on a patient sample (a sample is typically blood, urine or cerebrospinal fluid (CSF)), to aid in the diagnosis or detection of disease.  The information found from a test can be used to:

  • Diagnose disease
  • Assess the extent of damage
  • Monitor the effectiveness of treatment
  • Confirm a person to be free from disease

Blood flows through all parts of the body, coming into direct contact with every organ and tissue.  Therefore a blood sample’s appearance and composition provide important information on what is happening in the various parts of the body!

So what exactly is being tested in the blood?

Examples of substances that may be tested for the blood include proteins, nutrients, waste products, antibodies, hormones, salts, trace elements or vitamins.  These are sometimes referred to as ‘analytes’, ‘markers’ or ‘biomarkers’.

This is where reagents come in…

A reagent is a substance which is mixed with the patient sample to create a chemical reaction to detect the biomarker.  These reactions are analysed by machines known as analysers.

Finally…

Using data gathered from both clinical symptoms and laboratory tests, the doctor will follow a sometimes painstaking process of analysis and elimination to perform a successful diagnosis!

 

Continue reading…


Randox Reagents celebrate World Kidney Day 2017

On 9 March 2017, Randox Reagents are celebrating World Kidney Day!  World Kidney Day is a global campaign aimed at raising awareness of the importance of our kidneys to our overall health. It aims to reduce the frequency and impact of kidney disease and its associated health problems worldwide.

This year, the World Kidney Day promotes education on the harmful consequences of obesity and its association with kidney disease, advocating healthy lifestyle and health policy measures that make preventive behaviours an affordable option.

With this in mind, throughout the week we have been sharing on social media some interesting facts on diagnostic tests which can help aid an early risk assessment of kidney disease in obese patients, allowing preventative action to be taken before any serious damage occurs.  The tests of focus this week included cystatin C, adiponectin and microalbumin

Cystatin C

The creatinine test is routinely run for patients who are suspected for deteriorating kidney function, however this test has limitations.  Cystatin C is an alternative test, and is particularly useful in patients where creatinine measurements are not suitable e.g. individuals who are obese, malnourished, have liver cirrhosis or reduced muscle mass. Importantly, unlike creatinine, cystatin C does not have a ‘blind area’ – up to 50% of kidney function can be lost before significant creatinine elevation occurs. Cystatin C is extremely sensitive to very small changes in kidney function and is therefore capable of detecting early stage kidney dysfunction.  The cystatin C test therefore allows preventative measures to be taken much earlier and before significant kidney function decline.

Adiponectin

There is substantial evidence that excess visceral fat is the main driving force for almost all of the disorders associated with the metabolic syndrome, including CKD.1,2 The adiponectin test from Randox can accurately assess levels of abdominal visceral fat, independent of age, race or fitness level.3,4  Assessing adiponectin, and therefore visceral fat levels, can help assess risk of CKD, as well as a range of other illnesses such as pre-diabetes, CVD and various cancers.

 

Microalbumin

The microalbumin test detects very low levels of a blood protein called albumin, in urine. The detection of albumin in urine can be an indicator of kidney injury and can result in irreversible damage if left untreated. Low albumin concentrations in the urine are the earliest marker of kidney damage and therefore enable preventative measures to be taken.  Microalbumin testing can identify individuals with diabetic nephropathy approximately 5-10 years earlier than proteinuria tests helping reduce the frequency of end stage renal disease.

Both World Kidney Day and Randox are working towards improving healthcare worldwide. With continuous investment in R&D, Randox are helping with the risk assessment and earliest detection of renal function problems. By assessing one’s risk of kidney problems (with the adiponectin test), it can give patients (obese and other) the tools to prevent kidney problems further on down the line.  With early diagnosis (through the cystatin C and microalbumin tests) it will be possible to keep kidney problems from getting worse, therefore lowering the number of those diagnosed with CKD worldwide.

For health professionals

If you are a clinician or lab interested in running renal function assays, Randox offers a large range of high quality routine and niche assays including:  Cystatin C, Creatinine Enzymatic and Jaffe, Microalbumin, Urinary Protein, Urea, Sodium, Potassium, Albumin, Ammonia, β2- Microglobulin, Calcium, Chloride, Glucose, HbA1c, IgG, LDH, Magnesium, Phosphorus (Inorganic), and Uric Acid. These can be run on most automated biochemistry analysers.

For more information, download our Diabetes Brochure or email reagents@randox.com.

References

  1. Hall JE, Henegar JR, Dwyer TM, et al. Is obesity a major cause of chronic renal disease?Adv Ren Replace Ther. 2004;11(1):41–54. [PubMed]
  2. Tchernof A, Després JP. Pathophysiology of human visceral obesity: an update.Physiol Rev. 2013;93(1):359–404. [PubMed]
  3. Matsuzawa, Y. The role of fat topology in the risk of disease.  Int J Obes.  2008;32:s83-s92.
  4. Frederiksen, L., Nielsen, T. L., Wraae, K., Hagen, C., Frystyk, J., Flyvbjerg, A., Brixen, K. and Andersen, M. Subcutaneous Rather than Visceral Adipose Tissue Is Associated with Adiponectin Levels and Insulin Resistance in Young Men.  JCEM, (2009) 94 (10): 4010-4015.

 

Further reading:


What is Measurement of Uncertainty?

Measurement Uncertainty (MU) relates to the margin of doubt that exists for the result of any measurement, as well as how significant the doubt is. For example, a piece of string may measure 20 cm plus or minus 1 cm, at the 95% confidence level. As a result, this could be written: 20 cm ±1 cm, with a confidence of 95%. Therefore, we are 95% sure that the piece of string is between 19 cm and 21 cm long.

Standards such as ISO 15189 require that the laboratory must determine uncertainty for each test. However, they have not specified how this should be done.

How do we calculate Measurement Uncertainty using QC data?

Employing your QC data to calculate uncertainty makes several assumptions; your test system is under control, the patient samples are treated in the same manner as your controls and gross outliers have been removed. If you choose to use your QC data to calculate this you should ensure that you use a commutable control with a matrix similar to that of a patient sample, with analytes present at clinically relevant levels

To calculate MU, labs must look at the intra-assay precision and inter-assay precision of their test.

Intra-assay precision: Sometimes known as ‘within run’ precision, is where 20 or more replicates of the same sample are run at the same time, under the same conditions (calculated from a single experiment). Intra-assay precision helps to assess systematic uncertainties

Inter-assay precision: Sometimes known as ‘between run’ precision, is where 20 or more replicates are run at different times – e.g. 1 replicate every day for 20 days (can be calculated from routine IQC data). Inter-assay precision can help identify random uncertainties within the test system.

*The Australian Association of Clinical Biochemists (AACB) recommends that at least 6 months’ worth of QC data are used when calculating the inter-assay precision1.

Once the data is collected, you must calculate the standard error of the mean (SEM) of the intra-assay precision (A) and the SD of the inter-assay precision (B) in order to measure the uncertainty (u). Once A and B have been calculated, they need to be squared, added together and the square root of the sum found:

As uncertainty is calculated as SD and 1SD is equal to 68% confidence on a standard Gaussian curve, we can conclude that if we multiply using a coverage factor of 2, we can attain 2SD confidence of 95%. This is known as the Expanded Uncertainty (U):

What is the Advantage of Measurement Uncertainty for a lab?

Labs need to carry out MU as it is a requirement of ISO 15189. It states: “The laboratory shall determine measurement uncertainty for each measurement procedure, in the examination phases used to report measured quantity values on patients’ samples. The laboratory shall define the performance requirements for the measurement uncertainty of each measurement procedure and regularly review estimates of measurement uncertainty”.

MU also helps determine whether the difference between two results is negligible due to uncertainty or significant due to a genuine change in condition of the patient; giving labs a greater confidence in reported results.

How can Randox help?

Our new Acusera 24.7 Live Online software provides automatic calculation of MU, saving valuable time and helping labs meet ISO 15189 requirements with ease.

Contact marketing@randox.com to find out how your lab can benefit from Acusera 24.7 Live Online


Take steps to prevent incorrect patient results by making one simple change

According to the NHS Litigation Authority; in 2015 within the UK alone, £193,680,744.30 was spent on ‘wrong diagnosis’ or ‘failed/delayed diagnosis’ causing huge financial strain and impact on labs.

With approximately 75% of clinical decisions and diagnosis based on laboratory test results. The only way to guarantee a high degree of accuracy is to implement a good Quality Control plan. The importance of this is recognised globally, several bodies exist internationally including ISO (International organisation for standardisation) who have developed a set of guidelines and quality systems to ensure the reliability of laboratory test results.

So what can you do to improve accuracy and reliability?

Choose a third party QC

ISO 151589:2012 Section 5.6.2.2 states that “the use of third party control materials should be considered, either instead of, or in addition to, any control materials supplied by the reagent or instrument manufacturer”.

First Party Controls are those manufactured by the instrument/reagent manufacturer. These controls are optimised specifically for use with the manufacturers test system and therefore will mask a multitude of weaknesses. First Party Controls tend to result in perceived accuracy and a biased assessment of performance.

Third Party Controls on the other hand are designed to be completely independent  and are not optimised for use with a specific test or system. Leading manufacturers of third party controls will assign target values based on data collected from thousands of independent laboratories, ensuring the availability of statistically robust multi-method, multi-analyser data. Therefore laboratories using Third Party Controls can be assured of unbiased error detection across multiple platforms.

Randox Acusera is a world leading manufacturer of true third party controls providing a cost effective, high quality solution for any laboratory-regardless of size or budget.

Look out for QC samples with clinically relevant concentrations

ISO 15189:2012 states that ‘The laboratory should choose concentrations of control materials wherever possible, especially at or near clinical decision values, which ensure the validity of decisions made’.

It is important to assess the full clinical range of an assay i.e. the range between the lowest and highest results which can be reliably reported. In order to make sure a laboratory instrument is performing accurately across the full clinical range and in particular at the medical decision level, QC materials that cover low, normal and elevated concentrations should be used.

Due to the superior manufacturing process used by Randox, QC target values consistently cover the MDL of tests. By ensuring the controls in use cover clinical decision levels laboratories can be confident of the reliability and accuracy of the patient results they release.

Opt for a commutable control material

A good QC material has many essential properties but above all, controls must perform consistently and reflect the performance of patient samples – if a control meets these requirements then we can say it is commutable. Having a commutable control would aid in the prevention of incorrect patient results because they replicate the performance of a patient sample and react to the test system in a similar manner. Use of a commutable control will also reduce costly shifts in QC target values when reagent batch is changed.

At Randox we take quality seriously, that’s why all QC products are manufactured to the highest possible standard, delivering controls of unrivalled quality. Designed to be commutable, the Acusera range will ensure accurate and reliable instrument performance while simultaneously helping laboratories to meet ISO 15189:2012 requirements. A good QC process will include the use of Third Party Controls, Clinically Relevant Concentrations and controls which can be described as commutable. By employing Quality Control’s that encompass these traits, a laboratory professional can be certain that they have taken the necessary steps to decrease incorrect results and therefore potential misdiagnosis.


Randox Horse Tales | Mike Hughes and “The Greatest Horse of Aintree”

This week in the third edition of Horse Tales we are thrilled to hear from Mike Hughes,  Sports Broadcast Journalist for BBC Radio Merseyside.

Mike talks about Red Rum, “The Greatest Horse of Aintree,” and how the race conditions have changed since the millennium bringing with them the best chasers competing to win the world’s most famous race:

Even a cursory glance down the list of previous Grand National winners will highlight some seriously talented racehorses. Factor in the way the race conditions have changed since the new millennium, not to mention the incredible prize money on offer, then it’s not surprising that the very best chasers around are now competing to win the world’s most famous race.

But whatever the future holds for the race that sits at the centrepiece of the three day Aintree festival, there will only ever be one horse that can lay claim to being “The Greatest” that the famous old course has ever seen.

The Red Rum story is a remarkable one by any sporting standards. His love affair with the Grand National knew no bounds. In 1973 he came from “another parish” to pounce and steal victory on the run-in from Australian wonder horse Crisp. He became a National Hero from that point onwards. He broke the course record that year and the time has only been bettered once since.

Red Rum defended his Grand National title in 1974 with an incredible performance. Under the guidance of Brian Fletcher, he pretty much cruised around Aintree as if he owned the joint. He won the race with a swagger and poise that hasn’t been seen since. It was also an outstanding weight carrying performance. Red Rum was top weight in 1974. No horse carrying top weight has won it since.

In the 1975 & 1975 Grand National’s Red Rum was a gallant second. Firstly running a previous Gold Cup winner L’escargot close and then finishing runner up to the well handicapped Rag Trade.

By the time of the 1977 Grand National surely the passing of the years would diminish the chances of another Aintree ” day to remember” for Red Rum. Despite carrying another welter burden and being now aged 12, he put in yet another display of near faultless jumping over the toughest of fences and delivered another emphatic Grand National success. The only horse to win the race three times.

The courage of the horse is highlighted by the fact that he was engaged to run in the Grand National in 1978, but withdrew on the eve of the race due to a minor injury.

If the romantic notion of a horse who was housed in a stable behind a used car showroom in Southport, isn’t enough to convince you of Red Rum’s place in the pantheon of sporting greats then consider this.

If it wasn’t for Red Rum, then the Grand National as a sporting spectacle beyond compare, would probably not exist.

Red Rum and his loveable and outrageous trainer Ginger McCain began writing folklore history at the very same time that the world’s greatest race was under real threat of losing its Aintree home. The owners of the course in the mid 70’s were The Walton Group, property developers who outlined various proposals for Aintree, none of which would have allowed the Grand National to continue.

Red Rum became the popular galvanising force that made ordinary people take notice of this once a year event again. He was the horse and the story that put the Grand National back on the front pages of the world’s newspapers.

When we remember this year as the fortieth anniversary of Red Rum’s third and final Grand National victory we need also to think back ten years earlier, April 7th 1967. It was the horse’s first ever Aintree appearance, as a two year old in a five furlong flat race. Red Rum was never known for his flat racing pedigree, but this was the day he fell in love with this very special racecourse. He dead-heated for first place.

Red Rum’s record and his place in history means that he really is “The Greatest Horse of Aintree”

For more information about Randox Horse Tales please contact Randox PR on 028 9445 1016 or email RandoxPR@randox.com


We Are Randox | Kathleen Keery named Randox Employee of the Year 2016 at the 3rd Annual Manufacturing Awards Dinner

Randox Packing Department Team Member Kathleen Keery has been named Randox Employee of the Year 2016.

Her award was announced on Friday 24th February 2017, when 139 staff from 34 manufacturing departments of Randox gathered together at The Templeton Hotel in Templepatrick, to connect with colleagues and celebrate the success of their teams at the annual Randox Manufacturing Awards Dinner.

John Campbell, Senior Manager began the evening with his opening address, and thanked all attendees for their hard work;

“Each year our manufacturing department grows in strength and this is thanks to the people working in it.  I am proud to be standing here to recognise our collective capabilities as a team and to celebrate our hard work – with good food and great company.”

Lean Co-Ordinator, Mark Campbell then shared an overview of the year’s manufacturing successes, and looked forward to the activities for the year ahead.

On the night, the following awards were presented:

  • Employee of the Month October 2016 was awarded to Jeanette Robb within our Packing Department.
  • Employee of the Month November 2016 was won by Lisa McHendry of our Conjugate / Antibody Production Team.
  • December 2016’s Employee of the Month was Gareth Bushe of Randox Speciality Controls.
  • The Randox Logistics Department was then named as Department of the Year 2016.

Following the presentation of these awards, all attention turned to Senior Manager John Campbell to announce the prestigious Employee of the Year Award 2016.

We are delighted to be able to share that this award went to Kathleen Keery of our Packing Department.

Kathleen commented;

“I am beyond proud to be able to say that I am Randox Employee of the Year 2016.  I work in such a talented and hard-working team at Randox, so I know there must have been fierce competition!  It was an incredible honour to be able to receive this award surrounded by my colleagues and friends and I would like to thank everybody who has congratulated me over the past number of days.  All the work we do at Randox is truly a team effort and so my award is as much for my team members within the Packing Department as it is for me.  I wouldn’t be able to do my job without them!”

John Campbell closed the night by congratulating Kathleen, and the Logistics team;

“I’d like to take this opportunity to congratulate our award winners this evening – particularly the Logistics Team and Kathleen Keery – and to thank you all for the important part you play in making Randox a global leader in the diagnostics industry – manufacturing our products that we distribute all over the globe. Let’s look forward to an exciting and prosperous 2017 together, and I hope you enjoy the evening!”

For more information about the Manufacturing Awards please contact Randox PR by email: randoxpr@randox.com or phone 028 9442 2413


Ready, Set, Go: Randox Teoranta sponsors WAAR three years in a row

On Saturday 25th February, Ireland’s most famous adventurer, Jason Black, launched this year’s WAAR event, which is being sponsored for the third time by Randox Teoranta.  The Wild Atlantic Adventure Race which takes place in the Banks, Mullaghdearg, Donegal, raises much needed funds for the ongoing developments at CLG Naomh Mhuire.

World renowned adventurer, Jason Black commented;

“The Wild Atlantic Adventure Race is a brilliant event – an incredible physical challenge in a stunning location. I’m delighted to be involved, and encourage people to become active and set themselves goals. Whether it be climbing Mount Everest or powering through the WAAR, there’s a personal satisfaction that you get from sport that is so unique. That people not just from Ireland but overseas take part as well says all you need to know about the quality of this adventure race.”

With an anticipated 500 plus competitors hoping to take part this year on the 13th May, the race will include a 42.5k cycle, a 2K hike, and a 1K kayak. Adding an extra challenge, this year’s run has been increased by 2.5K to 10K offering contenders a day packed full of activities.

Ciaran Richardson, Head of R&D at Randox Teoranta in Dungloe, who is looking forward to supporting the event for a third time said;

We are delighted to sponsor the WAAR for a third consecutive year. The whole Donegal community looks forward to it and it’s a significant event promoting the importance of health, fitness and wellbeing. As a global diagnostics company we aim to revolutionise healthcare and WAAR gives us the perfect opportunity to spread our message of preventive health. We are looking forward to the event which is set to be a great success and hopefully we’ll be cheering on some of our own employees at the starting line again this year. “

WAAR committee member, Gavin Ó Dónaill, thanked Randox for their support and commented;

We are thrilled that Randox Teoranta have been named the 2017 sponsors of WAAR.  Without their sponsorship the event would not be possible. This year is set to be the biggest and best yet with an anticipated 500 plus competitors taking part. We have extended the distance of the run to 10K so there will be an added pressure to reach the finish line. We have also introduced a shorter sprint 39K Category to allow more newcomers to participate in WAAR. 

At the launch we will also be interviewing local members of the community who have in recent years become more involved in fitness and exercise through walking, running and cycling and have now registered to take part in the event. This represents the true spirit of WAAR.”

Saturday’s event will also include a new element in the form of a nutritional workshop by husband and wife, Jenna Maltese and Tom Coleman, the founders of My Nutrition Ireland who will offer simple effective food guidance to all attendees on the day.

For more information about the WAAR please contact Randox PR on 028 9445 1016 or email RandoxPR@randox.com


Northern Ireland children are first in the UK to see Randox Health Grand National Trophy 2017

Last week schoolchildren in Northern Ireland were the first in the UK to get to see the 2017 Randox Health Grand National trophy, when Randox Health took it on a schools tour across Northern Ireland.

A visit to Crumlin Integrated College in the town where Randox is based kicked off the tour, which marked the first time in the history of the race that the Grand National trophy has visited Northern Ireland.

The trophy made an appearance at schools in Belfast, Derry, Armagh, Omagh and Antrim, including St. Oliver Plunkett’s Primary School, the primary school attended by Sir Anthony McCoy.  The children at each school had the chance to learn more about Randox’s message of preventive health and were also offered the opportunity to take a trophy selfie!

Dr. Peter FitzGerald, Founder and Managing Director of Randox Health, commented;

“We are very proud of our roots and the support of people in Northern Ireland has played a significant part in our global success. This is an opportunity to share the excitement of the build-up of the Randox Health Grand National with children here, and also importantly to help spread the message of preventive health.

“No other race is as popular as this so it is rightfully called The People’s Race. It is our commitment to improving the health of people right across the world that led to this sponsorship. We hope that as a result people will learn about a more proactive and positive way to stay healthy and enjoy the magical moments that life gives us.”

Lynda McGarry, Principal of Crumlin Integrated College, welcomed the tour and the visit to the Crumlin school, which is also hosting St Joseph’s, Crumlin Integrated Primary School and Gaelscoil Ghleann Darach;

“We are absolutely thrilled that the children of each of our schools in Crumlin will be able to see the Randox Health Grand National Trophy up close and personal.  Horse racing is such a popular sport in Northern Ireland and so many of our pupils watch the Grand National at home with their families. To be able to share in the excitement leading up to the race is a fantastic opportunity for them and they are all looking forward to watching the race in April and finding out who will win the trophy that visited our school.

“We’re grateful to Randox for providing our pupils with such a special experience that they will remember for a very long time, and are very proud that the company, which is just down the road from us, is partnering with the world’s greatest race, and that Dr. FitzGerald chose Crumlin Integrated College to be the first school to see this special trophy.

“We are delighted that our Head Boy Brian Savage was able to unveil the trophy at our special assembly in front of a packed hall of pupils, staff and invited guests including politicians from all of the main parties.”

The Randox Health Grand National Trophy Tour of Northern Ireland cames after an announcement that for the first time ever, the title partner of the Randox Health Grand National will create a different winner’s trophy for each of the 5 years of its sponsorship, and each member of the winning team – owner, trainer, jockey groom – will receive their own version.

The Randox Health Grand National 2017 Trophy Tour of Northern Ireland was as follows:

Tuesday 21st February

Crumlin Integrated College – hosting St Joseph’s, Crumlin Integrated Primary School and Gaelscoil Ghleann Darach

Oakwood Special Needs School

Victoria College Primary School

Ashfield Boys High School

Wednesday 22nd February

Antrim Grammar

St Oliver Plunkett’s Primary School **(AP McCoy’s Primary School)

Dalriada Grammar School

Bushmills Primary School

North Coast Integrated College

Thursday 23rd February

Templepatrick Primary School

Loanends Primary School

Wallace High School

Thursday afternoon – Randox Health Holywood Clinic

Friday 24th February

Royal School Armagh

Omagh Academy

Strabane Academy

St Cecilia’s College

 

For more information about the 2017 Randox Health Grand National Trophy Tour of Northern Ireland please contact Randox PR on 028 9445 1016 or email RandoxPR@randox.com


Randox Horse Tales | Ed Chamberlin’s favourite Grand National memories

In the second edition of Randox Horse Tales, we’re delighted to be able to hear from the face of ITV Racing, Ed Chamberlin.

Read on to find out about his earliest racing memory, his first trip to Aintree, and why 2010 was his favourite Grand National…

The Randox Health Grand National has always been a huge part of my life.

My earliest memory is watching Aldiniti’s famous win in 1981 alongside my grandfather in his tiny sitting room in Bruton, though the fairytale was lost on his seven-year-old grandson who was fuming after his 50p on Spartan Missile narrowly failed to deliver. I remember blaming the jockey, again blissfully unaware of the heroics in the saddle from 54-year-old John Thorne.

From that day on I was in charge of my grandfather’s ITV7 entry and the annual family sweepstake. I was hooked.

My first trip to Aintree was in the election year of 1992 when Party Politics was an appropriate winner. I absolutely loved that giant horse and loved even more the huge price he returned on the Tote.

The trip North became an annual excursion, at first via a Little Chef Lodge off the M6 to the Canal Turn, and then when student days were over, a hotel stay and badges to the main enclosure with much of the day spent desperately trying to get in camera shot behind Des Lynam.

To think on 8th April I am going to present the 2017 Randox Health Grand National on ITV is utterly surreal. I cannot wait.

Party Politics holds a special place in my heart but my favourite winner of all time has to be Don’t Push It in 2010.

I had given up hope of AP McCoy ever riding a National winner. Everyone knew his obsession with winning the race – the one big omission from his remarkable CV – and every year seemed to end in bitter disappointed. Blowing Wind’s fall and Clan Royal getting carried out at Becher’s Brook were the two golden opportunities that got away and it looked like victory would never happen.

On the Monday before the 2010 renewal I spoke to AP, who was leaning towards riding Can’t Buy Time in the big race. Thankfully Jonjo O’Neill persuaded him otherwise later in the week.

The race itself went like clockwork and the feeling on the run-in when Don’t Push It hit the front and AP’s elation when he crossed the line, are memories I will never forget. The rest is a haze! Knowing just what it meant to the greatest jockey we will ever see, and his family, made that the most special Grand National day I can remember.

A few weeks later, the party to celebrate was pretty special too!

For more information about Randox Horse Tales please contact Randox PR on 028 9445 1016 or email RandoxPR@randox.com


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